Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.

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Year : 2026 | Volume : 3 | 02 | Page :
    By

    Prof Atul Khajuria,

  • Prabhdeep Singh,

  • Tapaswi Ram Khajuria,

  • KIRAN KUMARI,

  1. DEAN, Department of Allied and Health Care Sciences, Faculty of Allied and Health Care Sciences, Rayat Bahra Professional University, Punjab, India
  2. Assistant Professor, Department of Allied & Healthcare Sciences, Faculty of Allied & Healthcare Sciences, Rayat Bahra Professional University, Punjab, India
  3. Retd. Lecturer, Department of Education, Govt. Higher Sec School, Barola Udhampur J&K, Udhampur J&K, India
  4. Retd. Govt. Mater, Department of Education, Govt. High School, Pachote, Chenani, Udhampur J&K, Udhampur J&K, India

Abstract

Rapid and accurate detection of wound infections in field settings remains a critical challenge in emergency and military medicine. Conventional microbiological diagnostics are time- consuming and laboratory-dependent. Bacteriophages, particularly lysogenic phages, offer high specificity toward bacterial hosts and can be engineered as diagnostic tools. A translational framework was developed for lysogenic bacteriophage cocktails embedded with fluorophore reporters for rapid, point-of-care wound diagnostics. Mechanisms of phage infection, lysogenic integration, and fluorophore expression were integrated with portable optical detection systems. Comparative evaluation with existing diagnostic modalities was performed. Phage-based fluorescent biosensors demonstrated high specificity, rapid detection (<30 minutes), and real-time visualisation of pathogenic bacteria. Lysogenic phages enabled sustained signal amplification through host integration, while fluorophore tagging allowed direct optical readouts. Multiplexed phage cocktails expanded detection coverage across polymicrobial infections. Lysogenic phage–fluorophore systems represent a novel class of smart, field-deployable diagnostic tools for wound infections. Their integration into portable platforms has the potential to revolutionise infection monitoring in resource-limited and emergency environments.

Keywords: Bacteriophage, Lysogenic, Phage–fluorophore systems, Escherichia coli, Microbiological diagnostics.

How to cite this article:
Prof Atul Khajuria, Prabhdeep Singh, Tapaswi Ram Khajuria, KIRAN KUMARI. Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.. International Journal of Virus Studies. 2026; 03(02):-.
How to cite this URL:
Prof Atul Khajuria, Prabhdeep Singh, Tapaswi Ram Khajuria, KIRAN KUMARI. Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.. International Journal of Virus Studies. 2026; 03(02):-. Available from: https://journals.stmjournals.com/ijvs/article=2026/view=249787


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Ahead of Print Subscription Review Article
Volume 03
02
Received 20/04/2026
Accepted 31/05/2026
Published 15/07/2026
Publication Time 86 Days
46

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