Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review

Year : 2024 | Volume :01 | Issue : 01 | Page : 19-24
By

Durgadevi A.

Hariram S.

Abstract

In this study, the vitamin D levels in fortified foods (including follow-on formula, baby porridge, and curd cheese dessert) and dietary supplements designed for infants were examined. Analytical assessments uncovered variations in vitamin D concentrations compared to the labeled values, fortified foods contain anywhere from 50% to 153% for supplements 8% to 177%. Instant follow-on formula and oil-based supplements typically aligned with or surpassed the labeled values, whereas ready-to-eat baby porridge consistently registered below the declared values (74–81%). The study suggests that relying solely on label information may lead to inaccurate estimations of vitamin D intake in infants, with potential for both underestimation and overestimation. Furthermore, the discrepancies observed in nutrition D concentrations spotlight the importance of regular monitoring and quality manage measures within the manufacturing and distribution of fortified meals and dietary dietary supplements for babies. Adequate nutrition D intake is critical for most effective bone health and immune function throughout infancy, making accurate estimation essential for preserving typical fitness and well-being. The findings underscore the need for greater transparency and accuracy in labeling practices in the infant nutrition industry. Additionally, healthcare experts must be vigilant in advising caregivers about capability variations in vitamin D content material and the significance of varied assets to ensure babies receive adequate vitamins for healthy increase and development. Further studies is warranted to discover the elements contributing to these discrepancies and to establish standardized tips for nutrition D fortification in little one foods and supplements.

Keywords: Vitamin D, Fortified Foods, Infants, Dietary supplements, HPLC

[This article belongs to International Journal of Nutritions(ijn)]

How to cite this article: Durgadevi A., Hariram S.. Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review. International Journal of Nutritions. 2024; 01(01):19-24.
How to cite this URL: Durgadevi A., Hariram S.. Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review. International Journal of Nutritions. 2024; 01(01):19-24. Available from: https://journals.stmjournals.com/ijn/article=2024/view=135451


References

  1. Allen RE, Dangour AD, Tedstone AE. Update of the vitamin D content of fortified foods and supplements in the UK N ational D iet and N utrition S urvey N utrient D atabank. Nutrition Bulletin. 2014 Sep;39(3):247–52.
  2. Verkaik-Kloosterman J, Seves SM, Ocké MC. Vitamin D concentrations in fortified foods and dietary supplements intended for infants: Implications for vitamin D intake. Food chemistry. 2017 Apr 15;221:629–35.
  3. Regulation, E. C. “No 1925/2006 of the European Parliament and of the Council of 20 December 2006 on the addition of vitamins and minerals and of certain other substances to foods.” OJEU 50 (2006): 26–38.
  4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the essential composition of infant and follow‐on formulae. EFSA Journal. 2014 Jul;12(7):3760.
  5. De Jong MH, Nawijn EL, Verkaik-Kloosterman J. Consumption of young child formulae in the Netherlands. European Journal of Nutrition. 2023 Feb;62(1):83–93.
  6. O’Hearn M, Erndt-Marino J, Gerber S, Lauren BN, Economos C, Wong JB, Blumberg JB, Mozaffarian D. Validation of Food Compass with a healthy diet, cardiometabolic health, and mortality among US adults, 1999–2018. Nature Communications. 2022 Nov 22;13(1):7066.
  7. Byrdwell WC, DeVries J, Exler J, Harnly JM, Holden JM, Holick MF, Hollis BW, Horst RL, Lada M, Lemar LE, Patterson KY. Analyzing vitamin D in foods and supplements: methodologic challenges. The American journal of clinical nutrition. 2008 Aug 1;88(2):554S–7S.
  8. Byrdwell WC, Exler J, Gebhardt SE, Harnly JM, Holden JM, Horst RL, Patterson KY, Phillips KM, Wolf WR. Liquid chromatography with ultraviolet and dual parallel mass spectrometric detection for analysis of vitamin D in retail fortified orange juice. Journal of Food Composition and Analysis. 2011 May 1;24(3):299–306.
  9. Verkaik-Kloosterman J, Beukers MH, Jansen-van der Vliet M, Ocké MC. Vitamin D intake of Dutch infants from the combination of (fortified) foods, infant formula, and dietary supplements. European journal of nutrition. 2017 Mar;56:581–90.
  10. Dwyer, Johanna T et al. “Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements.” Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems vol. 21 (2008): S83–S93. doi:10.1016/j.jfca.2007.07.010
  11. Dwyer JT, Picciano MF, Betz JM, Fisher KD, Saldanha LG, Yetley EA, Coates PM, Milner JA, Whitted J, Burt V, Radimer K. Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements. Journal of Food Composition and Analysis. 2008 Feb 1;21:S83–93.
  12. EFSA N. Panel (EFSA Panel on Dietetic Products Nutrition and Allergies), 2012. Scientific opinion on the tolerable upper intake level of vitamin D. EFSA Journal 2012; 10 (7): 2813, 45 pp.
  13. World Health Organization. Report: 8th FAO/WHO joint meeting on pesticide management and 10th session of the FAO panel of experts on pesticide management, 14–17 October 2014, Rome. World Health Organization; 2014.
  14. Garg S, Sabri D, Kanji J, Rakkar PS, Lee Y, Naidoo N, Svirskis D. Evaluation of vitamin D medicines and dietary supplements and the physicochemical analysis of selected formulations. The Journal of nutrition, health and aging. 2013 Feb 1;17(2):158–61.
  15. Canada H, for Canada BC, Canadian Paediatric Society. Nutrition for healthy term infants: recommendations from birth to six months. Canadian journal of dietetic practice and research: a publication of Dietitians of Canada= Revue canadienne de la pratique et de la recherche en dietetique: une publication des Dietetistes du Canada. 2012;73(4):204.
  16. Vaes AM, Brouwer-Brolsma EM, van der Zwaluw NL, van Wijngaarden JP, Berendsen AA, van Schoor N, van der Velde N, Uitterlinden A, Lips P, Dhonukshe-Rutten RA, de Groot LC. Food sources of vitamin D and their association with 25-hydroxyvitamin D status in Dutch older adults. The Journal of steroid biochemistry and molecular biology. 2017 Oct 1;173:228–34.
  17. Holick MF, Shao Q, Liu WW, Chen TC. The vitamin D content of fortified milk and infant formula. New England Journal of Medicine. 1992 Apr 30;326(18):1178–81.
  18. LeBlanc ES, Perrin N, Johnson JD, Ballatore A, Hillier T. Over-the-counter and compounded vitamin D: is potency what we expect?. JAMA internal medicine. 2013 Apr 8;173(7):585–6.
  19. Nimalaratne C, Sun C, Wu J, Curtis JM, Schieber A. Quantification of selected fat soluble vitamins and carotenoids in infant formula and dietary supplements using fast liquid chromatography coupled with tandem mass spectrometry. Food research international. 2014 Dec 1;66:69–77.
  20. Patterson KY, Phillips KM, Horst RL, Byrdwell WC, Exler J, Lemar LE, Holden JM. Vitamin D content and variability in fluid milks from a US Department of Agriculture nationwide sampling to update values in the National Nutrient Database for Standard Reference. Journal of dairy science. 2010 Nov 1;93(11):5082–90.
  21. Pehrsson PR, Patterson KY, Khan MA. Selected vitamins, minerals and fatty acids in infant formulas in the United States. Journal of Food Composition and Analysis. 2014 Nov 1;36(1-2): 66–71.
  22. Roseland JM, Holden JM, Andrews KW, Zhao C, Schweitzer A, Harnly J, Wolf WR, Perry CR, Dwyer JT, Picciano MF, Betz JM. Dietary supplement ingredient database (DSID): preliminary USDA studies on the composition of adult multivitamin/mineral supplements. Journal of Food Composition and Analysis. 2008 Feb 1;21:S69–77.
  23. Rubingh CM, Kruizinga AG, Hulshof KM, Brussaard JH. Validation and sensitivity analysis of probabilistic models of dietary exposure to micronutrients: an example based on vitamin B6. Food additives and contaminants. 2003 Oct 1;20(S1):S50–60.
  24. Recommendations, Nordic Nutrition. “Nordic Nutrition Recommendations 2012: Integrating nutrition and physical activity.” Nordic Council of Ministers: Copenhagen, Denmark 627 (2014).
  25. Veatch AE, Brockman JD, Spate VL, Robertson JD, Morris JS. Selenium and nutrition: the accuracy and variability of the selenium content in commercial supplements. Journal of Radioanalytical and Nuclear Chemistry. 2005 Mar;264:33–8.
  26. Verkaik-Kloosterman J, Beukers MH, Jansen-van der Vliet M, Ocké MC. Vitamin D intake of Dutch infants from the combination of (fortified) foods, infant formula, and dietary supplements. European journal of nutrition. 2017 Mar;56:581–90.
  27. Verkaik-Kloosterman J, Seves SM, Ocké MC. Vitamin D concentrations in fortified foods and dietary supplements intended for infants: Implications for vitamin D intake. Food chemistry. 2017 Apr 15;221:629–35.
  28. Yetley EA. Multivitamin and multimineral dietary supplements: definitions, characterization, bioavailability, and drug interactions. The American journal of clinical nutrition. 2007 Jan 1;85(1):269S–76S.
  29. Yetley EA. Assessing the vitamin D status of the US population. The American journal of clinical nutrition. 2008 Aug 1;88(2):558S–64S.

Regular Issue Subscription Review Article
Volume 01
Issue 01
Received February 1, 2024
Accepted February 14, 2024
Published March 1, 2024