Striking the Right Balance: The Role of n-3/n-6 Fatty Acid Ratio in Health and Strategies for Dietary Improvement.
The dietary balance between omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) is crucial in modulating inflammation and promoting optimal physiological function. Modern diets, particularly in industrialized countries, are skewed heavily in favor of n-6 fatty acids, often reaching ratios as high as 1:20 or more, compared to the ideal range of 1:1 to 1:4. This imbalance is associated with the pathogenesis of numerous chronic diseases, including cardiovascular conditions, obesity, diabetes, neurodegenerative disorders, and certain cancers
