Evolution and impact of forensic DNA typing in modern investigation

[{“box”:0,”content”:”[if 992 equals=”Open Access”]n

n

n

n

Open Access

nn

n

n[/if 992]n

n

Year : May 27, 2024 at 5:30 pm | [if 1553 equals=””] Volume : [else] Volume :[/if 1553] | [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] : | Page : –

n

n

n

n

n

n

By

n

[foreach 286]n

n

n

Umer Ali, Nabila iqbal, Hafiza Rabia Shafiq, Husnain Ahmad, Arooj Asalm, Asad Abbas, Kashif Nawaz, Sarmad Yousaf, Muhammad Kaleem Ullah Journal

n

    n t

  • n

n

n[/foreach]

n

n[if 2099 not_equal=”Yes”]n

    [foreach 286] [if 1175 not_equal=””]n t

  1. Student, Student, Student, Student, Student, Student, Student, Student Department of Biological Sciences, Tennessee State University Nashville,, Department of Zoology, University of Agriculture, Department of Zoology, University of Agriculture, Department of Zoology, University of okara, Department of Botony, University of Agriculture, Department of Biological Sciences, Tennessee State University Nashville,, Department of Biological Sciences, Tennessee State University Nashville,, Department of Chemistry, Government College University, Department of Biological Sciences, Tennessee State University Nashville, Tennessee, Faislabad, Faislabad, Okara, Fasialabad, Tennessee, Tennessee, Faisalabad, Tennessee USA, Pakistan, Pakistan, Pakistan, Pakistan, USA, USA, Pakistan, USA
  2. n[/if 1175][/foreach]

n[/if 2099][if 2099 equals=”Yes”][/if 2099]n

n

Abstract

nThe forensic DNA typing, sometimes called DNA fingerprinting. Immigration, paternity, and criminal investigations use forensic DNA typing. Forensic genetics today includes bodily fluid identification, fast DNA analysis, forensic microbiology, and phenotypic profiling.
Human cells contain DNA, a molecular code. Human DNA sequences are 99.9% same in everyone. Every person has almost 0.1% unique DNA. Forensic experts also worry about this 0.1 percent of DNA that is unique. There are several steps undertaken during analysis of forensic DNA. These steps are sample preparation, DNA extraction, amplification, quantification, and DNA profile matching.
Parentage testing, mass tragedies, and crime scene investigations have relied on forensic DNA techniques. An individual’s genetic makeup is built on DNA. DNA can be isolated from living and dead people due to its stability.
Using DNA from crime scene samples, forensic DNA phenotyping shows a person’s biogeography, ancestry, appearance, and age. It is experienced in criminal situations where forensic STR profiling has no match since the donor sample is unknown to the investigators.
In his leukocyte cellular function research, Friedrich Miescher extracted DNA from cellular components and proteins. The precipitate Friedrich found was completely different from protein. He extracted protein using basic composition analysis. Washing the leukocyte with HCL for weeks isolates the nuclei in water/ether. In this research we try to discuss DNA damaging and repairing recycling. Forensic DNA typing has transformed criminal investigations and resolutions. This technique has exonerated the wrongfully condemned, provided strong evidence of guilt for suspects, and identified prospective culprits using DNA databases in unresolved instances. However, alongside these advancements come challenges that must be addressed to fully realize the potential of forensic DNA analysis. One such challenge is the need for education and training to improve the interpretation of complex DNA profiles generated by NGS technologies. As these technologies become more widespread, forensic analysts must be equipped with the knowledge and skills to accurately interpret the wealth of data produced. However, alongside these advancements come challenges that must be addressed to fully realize the potential of forensic DNA analysis. One such challenge is the need for education and training to improve the interpretation of complex DNA profiles generated by NGS technologies.

n

n

n

Keywords: Forensic, Extracted, profiling, investigation, Statiscial. Emerging

n[if 424 equals=”Regular Issue”][This article belongs to International Journal of Molecular Biotechnological Research(ijmbr)]

n

[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in International Journal of Molecular Biotechnological Research(ijmbr)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

n

n

n

How to cite this article: Umer Ali, Nabila iqbal, Hafiza Rabia Shafiq, Husnain Ahmad, Arooj Asalm, Asad Abbas, Kashif Nawaz, Sarmad Yousaf, Muhammad Kaleem Ullah Journal. Evolution and impact of forensic DNA typing in modern investigation. International Journal of Molecular Biotechnological Research. May 27, 2024; ():-.

n

How to cite this URL: Umer Ali, Nabila iqbal, Hafiza Rabia Shafiq, Husnain Ahmad, Arooj Asalm, Asad Abbas, Kashif Nawaz, Sarmad Yousaf, Muhammad Kaleem Ullah Journal. Evolution and impact of forensic DNA typing in modern investigation. International Journal of Molecular Biotechnological Research. May 27, 2024; ():-. Available from: https://journals.stmjournals.com/ijmbr/article=May 27, 2024/view=0

nn[if 992 equals=”Open Access”] Full Text PDF Download[/if 992] n[if 992 not_equal=”Open Access”]

[/if 992]n[if 992 not_equal=”Open Access”]


n


n

n[/if 992]nn[if 379 not_equal=””]n

Browse Figures

n

n

[foreach 379]n

n[/foreach]n

n

n

n[/if 379]n

n

References

n[if 1104 equals=””]n

  1. Asplen CH. From crime scene to courtroom: integrating DNA technology into the criminal justice system. Judicature. 1999;83:144.
  2. Chong KW, Thong Z, Syn CK. Recent trends and developments in forensic DNA extraction. Wiley Interdisciplinary Reviews: Forensic Science. 2021 Mar;3(2):e1395.
  3. Aj J. Individual-specific” fingerprints” of human DNA. Nature. 1985;316:76-9.
  4. Kaplan LJ. Chemistry and crime: Investigating chemistry from a forensic science perspective. InTeaching Chemistry with Forensic Science 2019 (pp. 13-34). American Chemical Society.
  5. Ali U, Vungarala S, Tiriveedhi V. Genomic Features of Homologous Recombination Deficiency in Breast Cancer: Impact on Testing and Immunotherapy. Genes. 2024 Jan 26;15(2):162.
  6. Kayser M, De Knijff P. Improving human forensics through advances in genetics, genomics and molecular biology. Nature Reviews Genetics. 2011 Mar;12(3):179-92.
  7. Dror IE, Hampikian G. Subjectivity and bias in forensic DNA mixture interpretation. Science & Justice. 2011 Dec 1;51(4):204-8.
  8. Joh EE. Reclaiming abandoned DNA: The Fourth Amendment and genetic privacy. Nw. UL Rev.. 2006;100:857.
  9. Roth A. Machine testimony. Yale LJ. 2016;126:1972.
  10. Siems E, Strandburg KJ, Vincent N. Trade Secrecy and Innovation in Forensic Technology. Hastings LJ. 2022;73:773.Scherr, A. E. (2013). Genetic privacy and the Fourth
  11. Orts EW. Business persons: A legal theory of the firm. Oxford University Press, USA; 2013 Aug 29.

nn[/if 1104][if 1104 not_equal=””]n

    [foreach 1102]n t

  1. [if 1106 equals=””], [/if 1106][if 1106 not_equal=””],[/if 1106]
  2. n[/foreach]

n[/if 1104]

nn


nn[if 1114 equals=”Yes”]n

n[/if 1114]

n

n

[if 424 not_equal=””][else]Ahead of Print[/if 424] Subscription Review Article

n

n

[if 2146 equals=”Yes”][/if 2146][if 2146 not_equal=”Yes”][/if 2146]n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n

n[if 1748 not_equal=””]

[else]

[/if 1748]n

n

n

Volume
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424]
Received April 23, 2024
Accepted May 16, 2024
Published May 27, 2024

n

n

n

n

n

n function myFunction2() {n var x = document.getElementById(“browsefigure”);n if (x.style.display === “block”) {n x.style.display = “none”;n }n else { x.style.display = “Block”; }n }n document.querySelector(“.prevBtn”).addEventListener(“click”, () => {n changeSlides(-1);n });n document.querySelector(“.nextBtn”).addEventListener(“click”, () => {n changeSlides(1);n });n var slideIndex = 1;n showSlides(slideIndex);n function changeSlides(n) {n showSlides((slideIndex += n));n }n function currentSlide(n) {n showSlides((slideIndex = n));n }n function showSlides(n) {n var i;n var slides = document.getElementsByClassName(“Slide”);n var dots = document.getElementsByClassName(“Navdot”);n if (n > slides.length) { slideIndex = 1; }n if (n (item.style.display = “none”));n Array.from(dots).forEach(n item => (item.className = item.className.replace(” selected”, “”))n );n slides[slideIndex – 1].style.display = “block”;n dots[slideIndex – 1].className += ” selected”;n }n”}]