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International Journal of Composite and Constituent Materials International Journal of Cell Biology and Cellular Processes [Applied(e)] is a peer-reviewed hybrid open-access journal launched in 2015 that aims to stimulate the scientifically grounded exchange of ideas. It contains timely reviews and original …
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Small proteins’ function in cellular energy management
Abstract Submission Deadline : 30/11/2023
Manuscript Submission Deadline : 25/12/2023
Special Issue Description
New molecular information on how cells make sure that their energy supply is regulated to meet energy demand has been found by researchers at Duke-NUS Medical School. Their study, which was conducted in collaboration with scientists from Duke University in Durham, North Carolina, and the University of Melbourne in Australia, emphasizes the critical role microproteins play in the assembly of larger protein complexes inside mitochondria, the energy-producing cell components. Numerous disorders, including common conditions like heart failure, obesity, diabetes, and cancer, are characterized by mitochondrial dysfunction. The double membrane that surrounds mitochondria—often referred to as the cell’s powerhouses—defines its boundaries. An array of proteins that are part of the electron transport chain are found in the inner of the two membranes. The activities that take chemical energy from food sources and ultimately store it in adenosine triphosphate molecules, which are energy-rich, depend on this electron transport (ATP). The new information from the Duke-NUS cooperation demonstrates that small microproteins also referred to as peptides are essential for the development of the electron transport chain. They specifically appear to work together to facilitate and control the assembly of Complex III, one of the chain’s essential proteins. This activity permits the microproteins to participate in regulating the concentrations of the electron transport chain proteins and, subsequently, the energy supply in response to changes in energy demand.
Keywords
ATP , Electron transport chain , Heart failure , Mitochondria , Microproteins
Manuscript Submission information
Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.
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