Biomedical Applications of Green-Synthesized Cobalt Oxide Nanoparticles

Year : 2025 | Volume :12 | Issue : 01 | Page : 20-29
    By

    Vandana Vishwakarma,

  • Gourav Mishra,

  1. Student, Department of Biotechnology, Meerut Institute of Engineering and Technology (MIET), Meerut, Uttar Pradesh, India
  2. Assistant Professor, Department of Biotechnology, Meerut Institute of Engineering and Technology (MIET), Uttar Pradesh, India

Abstract

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The biomedical potential of cobalt oxide nanoparticles (Co3O4 NPs) synthesized via green methods is gaining recognition due to their biocompatibility and multifunctionality. This article reviews the antibacterial and anticancer properties of Co3O4 NPs synthesized using Delonix regia leaf extract. Characterization techniques confirmed their nanoscale size and uniform morphology. The antibacterial assay against Escherichia coli revealed significant activity, attributed to enhanced permeability and interaction with bacterial membranes. These findings highlight the promise of green-synthesized Co3O4 NPs for biomedical applications, including infection control and targeted cancer therapy. Harnessing nature’s resources, advanced green synthesis methods are revolutionizing nanoparticle production, offering eco-friendly and efficient alternatives to conventional chemical and physical techniques. Because of its exceptional physico-chemical characteristics, the green production of cobalt oxide nanoparticles stands out among these. This study highlights the role of Delonix regia leaf extracts in stabilizing cobalt oxide nanoparticle synthesis, utilizing their abundant functional groups. X-ray diffraction showed peaks between 31.42 and 65.28, with the highest intensity at 36.86, whereas UV-visible spectroscopy revealed a peak at 436 nm for the biosynthesized nanoparticles. The particle size, ranging from 15 to 35 nm, confirmed an average size of 20 nm. SEM analysis displayed uniformly spherical and slightly agglomerated particles. Interestingly, Gram-negative Escherichia coli was significantly inhibited by these green-synthesised nanoparticles. This creative method opens the door for long-term developments in nanotechnology while also highlighting the promise of green chemistry.

Keywords: Cobalt oxide nanoparticles, Antibacterial activity, Biocompatibility, Green synthesis, Biomedical applications, Cancer therapy

[This article belongs to Emerging Trends in Chemical Engineering (etce)]

How to cite this article:
Vandana Vishwakarma, Gourav Mishra. Biomedical Applications of Green-Synthesized Cobalt Oxide Nanoparticles. Emerging Trends in Chemical Engineering. 2025; 12(01):20-29.
How to cite this URL:
Vandana Vishwakarma, Gourav Mishra. Biomedical Applications of Green-Synthesized Cobalt Oxide Nanoparticles. Emerging Trends in Chemical Engineering. 2025; 12(01):20-29. Available from: https://journals.stmjournals.com/etce/article=2025/view=0

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Regular Issue Subscription Review Article
Volume 12
Issue 01
Received 30/12/2024
Accepted 03/01/2025
Published 10/01/2025
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