RRJoDFDP

A Comprehensive Review on Adiantum Incisum (Maidenhair)

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u00a0Praveen Kumar Goyal, Gurpreet Singh,

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nAbstract

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A traditional medicinal maidenhair fern Adiantum incisum member of pteridaceae family widely distributed in hilly areas has been reported for its traditional uses as a medicinal fern. The presence of active nutrients and their multifunctional roles make Adiantum spp. leaves perfect candidates for the production of phyto-pharmaceutical products. It is used traditionally as remedy in different disease conditions like diabetes, inflammation, skin disease, liver disorder, fever etc. It is important to clarify these health benefits to public due to the increasing need for prevention and treatment of chronic diseases. Although it is used widely around the country, single hand information about its ethnobotanical, phytochemical and pharmacological action is still lacking. Traditionally appreciated for its pharmacological properties by the various researcher maidenhair is still hard to recognized because of insufficient information. The aim of this review is to summarize all the traditional property of Adiantum incisum.

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Volume :u00a0u00a08 | Issue :u00a0u00a03 | Received :u00a0u00a0July 17, 2021 | Accepted :u00a0u00a0October 18, 2021 | Published :u00a0u00a0November 1, 2021n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue A Comprehensive Review on Adiantum Incisum (Maidenhair) under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]
Keywords Adiantum incisum, Fern, Traditional, Phyto-pharmacological, Diabetes

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References

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1. Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges
in monitoring safety. Front Pharmacol. 2014; 4: 177p.
2. Dias DA, Urban S, Roessner U. A historical overview of natural products in drug discovery.
Metabolites. 2012; 2(2):303-336p.
3. Veeresham C. Natural products derived from plants as a source of drugs. J Adv Pharm Technol
Res. 2012; 3(4):200-201p.
4. Kamboj VP. Herbal medicine. Current Science. 2000; 78:35-39p.
5. Sofowora A, Ogunbodede E, Onayade A. The role and place of medicinal plants in the strategies
for disease prevention. Afr J Tradit Complement Altern Med. 2013;10(5):210-229p.
6. Petrovska BB. Historical review of medicinal plants’ usage. Pharmacognosy Review. 2012; 6(11):
1-5p.
7. Gupta A, Tandon N. Indian Medicinal Plant, New Delhi: Indian Council of Medical Research (P)
Ltd. 2004; 288-290p.
8. WHO. Global Report on Traditional and Complementary Medicine. 2019: 124-128p.
9. Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. Indian herbs and herbal drugs used
for the treatment of diabetes. J Clin Biochem Nutr. 2007; 40(3):163-173p.
10. Pan C. Chen YG, Ma XY. Phytochemical constituents and pharmacological activities of plants
from the genus Adiantum: A review. Trop. J. Pharm. Res., 2011; 10: 681–692p.
11. Bhramchari G, Mondal S, Bhramchari AK, Chatterjee D. Phytochemical and Biological Activity
of Adiantum Species. Journal of scientific and industrials research. 2003; 154-169p.
12. Vadi R, Vats M, Hansraj A. capillus veneris linn. A systemic review on its ethnobotany,
phytochemical and pharmacological profile. Int. Journaal of ayurveda & Pharma research.
2017:5(6); 5-21p.
13. Sunil K, Vipin K. Antidiabetic, Hypolipidemic and Antioxidant activity of C. Lanecolatus leaves
extract. Journal of Herbs, species and medicinal plants. 2011; 17(2): 114-153p.
14. Yumkham SD, Elangbam M, Nongmaithem R et al. Maiden hair ferns (Adiantum L.,
Pteridaceae–Vittarioideae) of North East India: diversity, phytochemistry and utilization. Genet
Resour Crop Evol. 65 (4); 2018, 1-12p.
15. Dehdari S, Haji mehdipoor H. Medicinal Properties of Adiantum capillus-veneris Linn in
Traditional Medicine and Modern Phytotherapy: A Review Article. Iran J Public Health. 2018;
47(2):188-197p.
16. Wu CY. Outline of New China Herbals, Vol. 3, Shanghai, China, Shanghai Press of Science and
Technology, 1990; 664-668p.
17. Rastogi S, Pandey MM, Rawat AK. Ethno-pharmacological uses, phyto-chemistry and
pharmacology of genus Adiantum: A comprehensive review. Journal of Ethno-pharmacology.
2018; 215: 101-119p.
18. Jayaprasad B. Traditionally using anti-diabetic medicinal plants in Tamilnadu. International
Journal of Research in Pharmaceutical and Bioscience, 2012: 2(1):1-8p.
19. Kumar S, Saini M, Kumar V, Prakash O. Traditional medicinal plants curing diabetes: A promise
for today and tomorrow. Asian J. Tradit. Med., 2012; 7:178–188p.
20. Ahvazi M. Introduction of medicinal plant species with the most traditional usage in alamut
region. Iranian Journal of Pharmaceutical research. 2012; 11(1): 185-194p.
21. Ranjan V, Vats M, Gupta N, Sardana S. Anti diabetic potential of whole plant of adantum
capillus veneris linn and Adianum incisum forssk In STZ induced diabetic rat. IJPCR. 2014;
6(14):341-347p.
22. Anitha, V. R., Mohan T., Athiperumalsami and Sutha, S. Ethnobotanical plants used by Kanilkars
of Tirunelweli district, Tamilnadu to treat skin diseases. Ethno botanical Leaflets. 2008; 12: 171-
180p.
23. Ahmed A, Jahan N, Wadud A et al., Physico chemical and biological properties 0f adiantum
capillus veneris linn. An importance of unani system of medicine. International Journal Curr Res
Rev, 2012: 04(21);70-73p.
24. Attaullah, Zaheer-ud-din Khan, Taxonomic and ethanobotanical study of Pteridopyts of miandam
valley, Pakastan, Internatonal Journal of Bioscience. 2017: 3(10); 72-79p.
25. Rai S, Yadav SK, Mathur K. A Review Article on Adiantum Incisum. A world journal of
Pharmacy and Pharmaceutical science. 2016; 5(4): 861-867p.
26. Pullaiah. T, Chandrasekhar Naidu. K. Anti-diabetic plants in India and herbal based antidiabetic.
Research regency publishers New Delhi. 2003: 121-124p
27. Telagari M., Hullatti K. In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum
caudatum Linn and Celosia argentea Linn extracts and fractions. Indian Journal of
pharmacology. 2015; 47(4): 425-429p.
28. Tanzin R, Rahman S, Shakhawat Md. Medicinal potential of pteridophytes – an
antihyperglycemic and antinociceptive activity evaluation of methanolic extract of whole plants of
Christella dentate. Advances in Natural and Applied Sciences. 2013;7(1):67-73p
29. Ansari R, Ekhlasi-Kazaj K. Adiantum capillus-veneris. L: Phytochemical Constituents,
Traditional Uses and Pharmacological Properties: A Review. Journal of Advanced Scientific
Research. 2012, 3(4): 15-20p
30. Paul T, Das B, Apte KG. Evaluation of Anti-Hyperglycemic Activity of Adiantum Philippense
Linn a Pteridophyte in Alloxan Induced Diabetic Rats. Journal of Diabetes and Metabolism.
2012; 3(9): 2-8p
31. Shukla AK, Bukhariya V, Mehta J. Herbal remedies for diabetes: an overview. International
Journal of Biomedical and Advance Research. 2011; 2(1): 1-7
32. Guha bakshi DN, Sensarma P, Pal DC. Medicinal plants in India (vol-1). Published by Naya
Prokash, Kolkata, India, 1999: 345-348p.
33. Ramakrishnan P, Antonysamy JMA, Perumal S, Shibila T. Anti Inflammatory Activity of
Selected Pteridophytes from Western Ghats. Int J Complement Alt Med. 2017; 9(4): 307-310p.
34. Khanum S, Aklima D. Comparitive anti microbial and cytotoxic activity of crude extract of A.
incisum forsk. Europian Journal of Pharmaceutical & medicinal research, 2016, 3(4); 100-105p.
35. Dildar A, Khan Muhammad M. and Ramsha S. Comparative analysis of phenolics, flavonoids,
and antioxidant and antibacterial potential of methanolic, hexanic and aqueous extracts from
Adiantum incisum leaves. Journal of antioxidants. 2015; 394-409p.
36. Frank RP, Arurachalam G, Ziaudheen VM. Evaluation of Hepato-protective effect of Adiantum
Incisum Frosk Leaf. International research journal of pharmacy. 2012; 3(3): 230-234p.
37. Bhatia DK, Sharma AK. Anti-fertility effect of crude drug different of adiantum speies on
Reproductive organs of male albino rats. Biological Forum. 2010;2(2):88-93p.
38. Parihar P, Parihar L. Some petridophytes of medicinal importance from Rajasthan. Natural
product radiance. 2009:297-301p.

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[if 424 not_equal=”Regular Issue”] Regular Issue[/if 424] Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

ISSN: 2394-1944

Editors Overview

rrjodfdp maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

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    Praveen Kumar Goyal, Gurpreet Singh

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  1. Associate Professor, Associate Professor,Department of Pharmacognosy, Alwar Pharmacy College, M.I.A, Department of Pharmaceutics, Rajasthan University of Health Sciences,Rajasthan, Rajasthan,India, India
  2. n[/if 1175][/foreach]

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Abstract

nA traditional medicinal maidenhair fern Adiantum incisum member of pteridaceae family widely distributed in hilly areas has been reported for its traditional uses as a medicinal fern. The presence of active nutrients and their multifunctional roles make Adiantum spp. leaves perfect candidates for the production of phyto-pharmaceutical products. It is used traditionally as remedy in different disease conditions like diabetes, inflammation, skin disease, liver disorder, fever etc. It is important to clarify these health benefits to public due to the increasing need for prevention and treatment of chronic diseases. Although it is used widely around the country, single hand information about its ethnobotanical, phytochemical and pharmacological action is still lacking. Traditionally appreciated for its pharmacological properties by the various researcher maidenhair is still hard to recognized because of insufficient information. The aim of this review is to summarize all the traditional property of Adiantum incisum.n

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Keywords: Adiantum incisum, Fern, Traditional, Phyto-pharmacological, Diabetes

n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)]

n[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]

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References

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1. Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges
in monitoring safety. Front Pharmacol. 2014; 4: 177p.
2. Dias DA, Urban S, Roessner U. A historical overview of natural products in drug discovery.
Metabolites. 2012; 2(2):303-336p.
3. Veeresham C. Natural products derived from plants as a source of drugs. J Adv Pharm Technol
Res. 2012; 3(4):200-201p.
4. Kamboj VP. Herbal medicine. Current Science. 2000; 78:35-39p.
5. Sofowora A, Ogunbodede E, Onayade A. The role and place of medicinal plants in the strategies
for disease prevention. Afr J Tradit Complement Altern Med. 2013;10(5):210-229p.
6. Petrovska BB. Historical review of medicinal plants’ usage. Pharmacognosy Review. 2012; 6(11):
1-5p.
7. Gupta A, Tandon N. Indian Medicinal Plant, New Delhi: Indian Council of Medical Research (P)
Ltd. 2004; 288-290p.
8. WHO. Global Report on Traditional and Complementary Medicine. 2019: 124-128p.
9. Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. Indian herbs and herbal drugs used
for the treatment of diabetes. J Clin Biochem Nutr. 2007; 40(3):163-173p.
10. Pan C. Chen YG, Ma XY. Phytochemical constituents and pharmacological activities of plants
from the genus Adiantum: A review. Trop. J. Pharm. Res., 2011; 10: 681–692p.
11. Bhramchari G, Mondal S, Bhramchari AK, Chatterjee D. Phytochemical and Biological Activity
of Adiantum Species. Journal of scientific and industrials research. 2003; 154-169p.
12. Vadi R, Vats M, Hansraj A. capillus veneris linn. A systemic review on its ethnobotany,
phytochemical and pharmacological profile. Int. Journaal of ayurveda & Pharma research.
2017:5(6); 5-21p.
13. Sunil K, Vipin K. Antidiabetic, Hypolipidemic and Antioxidant activity of C. Lanecolatus leaves
extract. Journal of Herbs, species and medicinal plants. 2011; 17(2): 114-153p.
14. Yumkham SD, Elangbam M, Nongmaithem R et al. Maiden hair ferns (Adiantum L.,
Pteridaceae–Vittarioideae) of North East India: diversity, phytochemistry and utilization. Genet
Resour Crop Evol. 65 (4); 2018, 1-12p.
15. Dehdari S, Haji mehdipoor H. Medicinal Properties of Adiantum capillus-veneris Linn in
Traditional Medicine and Modern Phytotherapy: A Review Article. Iran J Public Health. 2018;
47(2):188-197p.
16. Wu CY. Outline of New China Herbals, Vol. 3, Shanghai, China, Shanghai Press of Science and
Technology, 1990; 664-668p.
17. Rastogi S, Pandey MM, Rawat AK. Ethno-pharmacological uses, phyto-chemistry and
pharmacology of genus Adiantum: A comprehensive review. Journal of Ethno-pharmacology.
2018; 215: 101-119p.
18. Jayaprasad B. Traditionally using anti-diabetic medicinal plants in Tamilnadu. International
Journal of Research in Pharmaceutical and Bioscience, 2012: 2(1):1-8p.
19. Kumar S, Saini M, Kumar V, Prakash O. Traditional medicinal plants curing diabetes: A promise
for today and tomorrow. Asian J. Tradit. Med., 2012; 7:178–188p.
20. Ahvazi M. Introduction of medicinal plant species with the most traditional usage in alamut
region. Iranian Journal of Pharmaceutical research. 2012; 11(1): 185-194p.
21. Ranjan V, Vats M, Gupta N, Sardana S. Anti diabetic potential of whole plant of adantum
capillus veneris linn and Adianum incisum forssk In STZ induced diabetic rat. IJPCR. 2014;
6(14):341-347p.
22. Anitha, V. R., Mohan T., Athiperumalsami and Sutha, S. Ethnobotanical plants used by Kanilkars
of Tirunelweli district, Tamilnadu to treat skin diseases. Ethno botanical Leaflets. 2008; 12: 171-
180p.
23. Ahmed A, Jahan N, Wadud A et al., Physico chemical and biological properties 0f adiantum
capillus veneris linn. An importance of unani system of medicine. International Journal Curr Res
Rev, 2012: 04(21);70-73p.
24. Attaullah, Zaheer-ud-din Khan, Taxonomic and ethanobotanical study of Pteridopyts of miandam
valley, Pakastan, Internatonal Journal of Bioscience. 2017: 3(10); 72-79p.
25. Rai S, Yadav SK, Mathur K. A Review Article on Adiantum Incisum. A world journal of
Pharmacy and Pharmaceutical science. 2016; 5(4): 861-867p.
26. Pullaiah. T, Chandrasekhar Naidu. K. Anti-diabetic plants in India and herbal based antidiabetic.
Research regency publishers New Delhi. 2003: 121-124p
27. Telagari M., Hullatti K. In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum
caudatum Linn and Celosia argentea Linn extracts and fractions. Indian Journal of
pharmacology. 2015; 47(4): 425-429p.
28. Tanzin R, Rahman S, Shakhawat Md. Medicinal potential of pteridophytes – an
antihyperglycemic and antinociceptive activity evaluation of methanolic extract of whole plants of
Christella dentate. Advances in Natural and Applied Sciences. 2013;7(1):67-73p
29. Ansari R, Ekhlasi-Kazaj K. Adiantum capillus-veneris. L: Phytochemical Constituents,
Traditional Uses and Pharmacological Properties: A Review. Journal of Advanced Scientific
Research. 2012, 3(4): 15-20p
30. Paul T, Das B, Apte KG. Evaluation of Anti-Hyperglycemic Activity of Adiantum Philippense
Linn a Pteridophyte in Alloxan Induced Diabetic Rats. Journal of Diabetes and Metabolism.
2012; 3(9): 2-8p
31. Shukla AK, Bukhariya V, Mehta J. Herbal remedies for diabetes: an overview. International
Journal of Biomedical and Advance Research. 2011; 2(1): 1-7
32. Guha bakshi DN, Sensarma P, Pal DC. Medicinal plants in India (vol-1). Published by Naya
Prokash, Kolkata, India, 1999: 345-348p.
33. Ramakrishnan P, Antonysamy JMA, Perumal S, Shibila T. Anti Inflammatory Activity of
Selected Pteridophytes from Western Ghats. Int J Complement Alt Med. 2017; 9(4): 307-310p.
34. Khanum S, Aklima D. Comparitive anti microbial and cytotoxic activity of crude extract of A.
incisum forsk. Europian Journal of Pharmaceutical & medicinal research, 2016, 3(4); 100-105p.
35. Dildar A, Khan Muhammad M. and Ramsha S. Comparative analysis of phenolics, flavonoids,
and antioxidant and antibacterial potential of methanolic, hexanic and aqueous extracts from
Adiantum incisum leaves. Journal of antioxidants. 2015; 394-409p.
36. Frank RP, Arurachalam G, Ziaudheen VM. Evaluation of Hepato-protective effect of Adiantum
Incisum Frosk Leaf. International research journal of pharmacy. 2012; 3(3): 230-234p.
37. Bhatia DK, Sharma AK. Anti-fertility effect of crude drug different of adiantum speies on
Reproductive organs of male albino rats. Biological Forum. 2010;2(2):88-93p.
38. Parihar P, Parihar L. Some petridophytes of medicinal importance from Rajasthan. Natural
product radiance. 2009:297-301p.

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Regular Issue Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

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[if 344 not_equal=””]ISSN: 2394-1944[/if 344]

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Volume 8
Issue 3
Received July 17, 2021
Accepted October 18, 2021
Published November 1, 2021

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Read More
RRJoDFDP

Kalyaanak Ghrita: A Medicinal Review

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By [foreach 286]u00a0

u00a0Gyanendra Kumar Gupta, Gagan Devi,

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nJanuary 24, 2023 at 8:20 am

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nAbstract

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Kalyaanaka ghrita is a formulation described by Aacaarya Vaagbhat in Unmaada pratishedha in Ashtaanga Hridaya Uthara sthaana and Aacaarya Caraka in Caraka samhita Cikitsa sthaana. Aacaarya Susruta has mentioned this yoga in Kalpa sthaana. The formulation which contains 28 drugs mentioned in Charaka samhita chikitsa sthaana is selected for the study. It is ideal in managing psychic derangements. Moreover, it has varied indications in reproductive domains as well. The combination is having multiple level of action in almost all systems of the body especially involving rasa, rakta and sukra dhatu. It improves ojus and is having rasayana property. Thus, it is a very good combination with proven psychological and reproductive action.

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Volume :u00a0u00a08 | Issue :u00a0u00a03 | Received :u00a0u00a0July 27, 2021 | Accepted :u00a0u00a0October 18, 2021 | Published :u00a0u00a0November 1, 2021n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue Kalyaanak Ghrita: A Medicinal Review under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]
Keywords Kalyaanaka Ghrita, Unmaada, Rasa, Rakta, Shukra Dhatu, Ojus and Rasayana.

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References

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1. Shawn D Youngstedt, et al. Does bright light have an anxiolytic effect? – an open trial. BMC
Psychiatry. 2007 Oct 30;7:62.
2. S E Buffett-Jerrott, et al. Cognitive and sedative effects of benzodiazepine use. Curr Pharm Des.
2002;8(1):45-58.
3. The Charakasamhita of Agnivesa Rev. by Charaka and Dridhabala, with the Ayurveda Dipika
commentary of Chakrapanidatta. 3rd edition. Munshiram Manoharlal Publishers PVT. LTD.1992.
4. Bhavmishra, Bhavaprakasha Samhita, editor pandit BSM, 11th edition, Varanasi: chaukhambha
sanskrita bhawan, 2012.
5. Bhela-Samhita (Text with English Translation, Commentary and Critical Notes) (Haridas
Ayurveda Series).by Dr K.H. Krishnamurthy; Edited by Prof. Priya Vrat Sharma. 2003
6. Kasyapa Samhita or Vrddhajivakiya Tantra, Text with English Translation and Commentary.by
P.V. Tewari. Chaukhambha Visvabharati; Reprint 2018 edition (30 January 2018)
7. Caraka Samhita- Ayurveda Dipika’s Ayusi Hindi Commentary (Vol-II). Chaukhambha Orientalia,
Varanasi; 2018th edition (April 1, 2018)
8. Susruta Samhita Nibandhasangraha Commentary Sri Dalhanacharya by Vaidya Yadavji Trikamji
Acharya. Chaukhamba Surbharti Prakashan (1 January 2014).
9. Ashtanga Hrdya Samhita Sasilekha Commentary Indu. by Shri Vahatacharya Chaukhambha (1
January 2007)
10. Ashtanga Hridaya with the commentaries, Sarvangasundara of Arundatta and Ayurveda rasayana
of Hemadri, edited by Pandit Hari Sadashiva Shashtri Paradakara Bhishag Acharya; 6th edition,
Varansi: Chaukhambha Surbharati Prakashan;2014.

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[if 424 not_equal=”Regular Issue”] Regular Issue[/if 424] Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

ISSN: 2394-1944

Editors Overview

rrjodfdp maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

n

“},{“box”:4,”content”:”

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    By  [foreach 286]n

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    Gyanendra Kumar Gupta, Gagan Devi

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    [foreach 286] [if 1175 not_equal=””]n t

  1. Professor & Head, Assistant Professor,Department of Physiology,RK Institute of Ayurvedic Medical Science Dewrania,Bareilly, Department of Anatomy, RK Institute of Ayurvedic Medical Science Dewrania, Bareilly,,Uttar Pradesh, Uttar Pradesh,India, India
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Abstract

nKalyaanaka ghrita is a formulation described by Aacaarya Vaagbhat in Unmaada pratishedha in Ashtaanga Hridaya Uthara sthaana and Aacaarya Caraka in Caraka samhita Cikitsa sthaana. Aacaarya Susruta has mentioned this yoga in Kalpa sthaana. The formulation which contains 28 drugs mentioned in Charaka samhita chikitsa sthaana is selected for the study. It is ideal in managing psychic derangements. Moreover, it has varied indications in reproductive domains as well. The combination is having multiple level of action in almost all systems of the body especially involving rasa, rakta and sukra dhatu. It improves ojus and is having rasayana property. Thus, it is a very good combination with proven psychological and reproductive action.n

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Keywords: Kalyaanaka Ghrita, Unmaada, Rasa, Rakta, Shukra Dhatu, Ojus and Rasayana.

n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)]

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References

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1. Shawn D Youngstedt, et al. Does bright light have an anxiolytic effect? – an open trial. BMC
Psychiatry. 2007 Oct 30;7:62.
2. S E Buffett-Jerrott, et al. Cognitive and sedative effects of benzodiazepine use. Curr Pharm Des.
2002;8(1):45-58.
3. The Charakasamhita of Agnivesa Rev. by Charaka and Dridhabala, with the Ayurveda Dipika
commentary of Chakrapanidatta. 3rd edition. Munshiram Manoharlal Publishers PVT. LTD.1992.
4. Bhavmishra, Bhavaprakasha Samhita, editor pandit BSM, 11th edition, Varanasi: chaukhambha
sanskrita bhawan, 2012.
5. Bhela-Samhita (Text with English Translation, Commentary and Critical Notes) (Haridas
Ayurveda Series).by Dr K.H. Krishnamurthy; Edited by Prof. Priya Vrat Sharma. 2003
6. Kasyapa Samhita or Vrddhajivakiya Tantra, Text with English Translation and Commentary.by
P.V. Tewari. Chaukhambha Visvabharati; Reprint 2018 edition (30 January 2018)
7. Caraka Samhita- Ayurveda Dipika’s Ayusi Hindi Commentary (Vol-II). Chaukhambha Orientalia,
Varanasi; 2018th edition (April 1, 2018)
8. Susruta Samhita Nibandhasangraha Commentary Sri Dalhanacharya by Vaidya Yadavji Trikamji
Acharya. Chaukhamba Surbharti Prakashan (1 January 2014).
9. Ashtanga Hrdya Samhita Sasilekha Commentary Indu. by Shri Vahatacharya Chaukhambha (1
January 2007)
10. Ashtanga Hridaya with the commentaries, Sarvangasundara of Arundatta and Ayurveda rasayana
of Hemadri, edited by Pandit Hari Sadashiva Shashtri Paradakara Bhishag Acharya; 6th edition,
Varansi: Chaukhambha Surbharati Prakashan;2014.

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Regular Issue Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

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[if 344 not_equal=””]ISSN: 2394-1944[/if 344]

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Volume 8
Issue 3
Received July 27, 2021
Accepted October 18, 2021
Published November 1, 2021

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RRJoDFDP

Navak Guggulu-The Drug of Choice in Sthoulya (Obesity)

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By [foreach 286]u00a0

u00a0Gyanendra Kumar Gupta, Gagan Devi,

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nJanuary 24, 2023 at 7:23 am

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nAbstract

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The Navaka Guggulu consists of 10 drugs along with Shuddha Guggulu and was prepared according to the principles of Tablet form. Navaka Guggulu is similar to the Medohara Guggulu in contents. Navaka Guggulu is mentioned in Medo rog. It is mentioned by Bhaishajya Ratnavali and Chakradutta.

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Volume :u00a0u00a08 | Issue :u00a0u00a03 | Received :u00a0u00a0July 30, 2021 | Accepted :u00a0u00a0October 14, 2021 | Published :u00a0u00a0November 10, 2021n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue Navak Guggulu-The Drug of Choice in Sthoulya (Obesity) under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]
Keywords Navaka Guggulu, Medohara Guggulu, Medoroga adhikar, Bhaishajya Ratnavali andChakradutta.

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References

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1. Rajput AS, et al. A pharmaceuticopharmaco-clinical study on Guggulu w.s.r. to Medohar effect.
(PG dissertation). Jamnagar: I.P.G.T. and R.A.;2003.
2. Digestion and Metabolism in Ayurveda, Chowkhamba Krtishnadas Academy 16 December 2013
3. Suhas V Nayak et al (A comparative pharmaceutico-pharmaco-clinical study of Tamra Bhasma
and Somanathi Tamra Bhasma w.s.r. to its Medohara effect.) 2006
4. Ankur Saxena, et al. A Clinical study on the Management of Sthaulya by Trikatu Churna.
International Ayurvedic Medical Journal. 2020
5. Tejal Khunt and S. Vyas A comparative study of Virechana Karma and Lekhana Basti in the
management of Sthaulya- International Journal of Pharmaceutical and Biological Archives 2012;
3(6):1445-1449.
6. Almagboul, A.Z, et al. Antimicrobial activity of certain sudanese plants used in folkloric
medicine. Screening for antibacterial activity. IV [1985]. AGRIS. 2013:56(6):331-337.
7. R S Ahmed, et al. Influence of dietary ginger (Zingiber officinales Rosc) on antioxidant defense
system in rat: comparison with ascorbic acid. Indian J Exp Biol. 2000 Jun;38(6):604-6.
8. Mehta S. and Shukla – Aetiopathological study of Sthaulya ( obesity ) and assessment of the effect
of the Devadarvyadi Vati and Virechana Karma – 2003
9. Pandya A. and Singh – The role of certain Ayurvedic anorexant Drugs in the management of
Sthaulya -1999.

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[if 424 not_equal=”Regular Issue”] Regular Issue[/if 424] Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

ISSN: 2394-1944

Editors Overview

rrjodfdp maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

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    By  [foreach 286]n

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    Gyanendra Kumar Gupta, Gagan Devi

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  1. Professor & Head, Assistant Professor,Department of Physiology,RK Institute of Ayurvedic Medical Science Dewrania,Bareilly, Department of Anatomy, RK Institute of Ayurvedic Medical Science Dewrania, Bareilly,,Uttar Pradesh, Uttar Pradesh,India, India
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Abstract

nThe Navaka Guggulu consists of 10 drugs along with Shuddha Guggulu and was prepared according to the principles of Tablet form. Navaka Guggulu is similar to the Medohara Guggulu in contents. Navaka Guggulu is mentioned in Medo rog. It is mentioned by Bhaishajya Ratnavali and Chakradutta.n

n

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Keywords: Navaka Guggulu, Medohara Guggulu, Medoroga adhikar, Bhaishajya Ratnavali andChakradutta.

n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)]

n[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]

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References

n[if 1104 equals=””]

1. Rajput AS, et al. A pharmaceuticopharmaco-clinical study on Guggulu w.s.r. to Medohar effect.
(PG dissertation). Jamnagar: I.P.G.T. and R.A.;2003.
2. Digestion and Metabolism in Ayurveda, Chowkhamba Krtishnadas Academy 16 December 2013
3. Suhas V Nayak et al (A comparative pharmaceutico-pharmaco-clinical study of Tamra Bhasma
and Somanathi Tamra Bhasma w.s.r. to its Medohara effect.) 2006
4. Ankur Saxena, et al. A Clinical study on the Management of Sthaulya by Trikatu Churna.
International Ayurvedic Medical Journal. 2020
5. Tejal Khunt and S. Vyas A comparative study of Virechana Karma and Lekhana Basti in the
management of Sthaulya- International Journal of Pharmaceutical and Biological Archives 2012;
3(6):1445-1449.
6. Almagboul, A.Z, et al. Antimicrobial activity of certain sudanese plants used in folkloric
medicine. Screening for antibacterial activity. IV [1985]. AGRIS. 2013:56(6):331-337.
7. R S Ahmed, et al. Influence of dietary ginger (Zingiber officinales Rosc) on antioxidant defense
system in rat: comparison with ascorbic acid. Indian J Exp Biol. 2000 Jun;38(6):604-6.
8. Mehta S. and Shukla – Aetiopathological study of Sthaulya ( obesity ) and assessment of the effect
of the Devadarvyadi Vati and Virechana Karma – 2003
9. Pandya A. and Singh – The role of certain Ayurvedic anorexant Drugs in the management of
Sthaulya -1999.

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  1. [if 1106 equals=””], [/if 1106][if 1106 not_equal=””],[/if 1106]
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n[/if 1114]”},{“box”:2,”content”:”

Regular Issue Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

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[if 344 not_equal=””]ISSN: 2394-1944[/if 344]

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Volume 8
Issue 3
Received July 30, 2021
Accepted October 14, 2021
Published November 10, 2021

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RRJoDFDP

Formulation Development and In Vitro Evaluations of Trimetazidine and Clopidogrel Bilayered Tablets

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By [foreach 286]u00a0

u00a0S.K. Godasu, D. Varun, Narmada Valla Keerthi, P. Deepika, N. Vijaya Rekha,

[/foreach]
nJanuary 10, 2023 at 7:16 am

n

nAbstract

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The Bilayered tablets consisting of Trimetazidine SR as well as Clopidogrel IR were efficiently prepared by damp granulation technique as well as straight compression approach specifically. The prepared powdered mix (SR) were also preserved the physiochemical residential or commercial properties of tablet computers such as thickness, firmness, weight variant, friability and drug material. The enhanced formula consists of the average thickness of 3.1 ± 0.034, average firmness of 4.2 ± 0.42, typical weight of 100 ± 1.06, friability of 0.417 and also 99.62% of medication content. The ready powdered blend (IR) were additionally preserved the physiochemical residential or commercial properties of tablets such as thickness, hardness, weight variation, friability and medication material. The optimized solution contains the average thickness of 2.7 ± 0.034, average hardness of 4.9 ± 0.42, average weight of 251 ± 0.96, friability of 0.408 and also 99.42% of medication content. Total it may be summed up that the tablet computer having bilayer Clopidogrel and also Trimetazidine will be a fantastic as well as reliable solution in dealing with subjects with the heart problem.

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Volume :u00a0u00a08 | Issue :u00a0u00a03 | Received :u00a0u00a0October 16, 2021 | Accepted :u00a0u00a0October 20, 2021 | Published :u00a0u00a0November 1, 2021n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue Formulation Development and In Vitro Evaluations of Trimetazidine and Clopidogrel Bilayered Tablets under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]
Keywords Trimetazidine, clopidogrel, Bilayered tablets, HPMC, CSD

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References

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1. SC Sweetman. Martindale, The comperhensive drug reference. Pharmaceutical Press; 36th Revised edition (March 16, 2009).
2. Wikipedia. Trimetazidine. 10 August 2021. Available online at: https://en.wikipedia.org/wiki/Trimetazidine.
3. G Fragasso, et al. Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure. Eur Heart J. 2006 Apr;27(8):942-8.
4. A Onay-Besikci; S Guner, et al. The effects of chronic trimetazidine treatment on mechanical function and fatty acid oxidation in diabetic rat hearts. Can J Physiol Pharmacol, 2007, 85(5), 527-35.
5. H Darius; T Münzel; K Huber; E Sultan; U Walter. Clopidogrel Salts -Pharmacokinetic, Pharmakodynamic and Clinical Aspects. Austrian Journal of Cardiology, 2009, 16(11-12), 412- 416.
6. L Hong–Qing; Z Shi –Yang, China National knowledge infrastructure (CNKI) journal, 2010, 21(4), 30-35.
7. Nuntakan S, Phensri T as well as Kaisri U. Transdermal Circulation of Zidovudine (AZT): The Effects of Vehicles, Boosters, and also Polymer Membranes on Permeation throughout Body Pig Skin. AAPS Pharm Sci Innovation 2004; 5(3):1-8.
8. Lachmann as well as Liebermann. The Theory as well as also Approach of Industrial Drug Store. CBS; 4th edition (1 January 2020).
9. Ansel. Drug Dosage forms. Medication shipment systems. Sixth variation, Pages. 196-203.
10. Herbert A. Liebermann. Medicine Dose kinds– Tablet computer computers – Vol.1, Marcel Dekker magazines, 2nd variation, Pages. 179-181.

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n[/if 1114]

n

n

[if 424 not_equal=”Regular Issue”] Regular Issue[/if 424] Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

ISSN: 2394-1944

Editors Overview

rrjodfdp maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

n

“},{“box”:4,”content”:”

n“},{“box”:1,”content”:”

    By  [foreach 286]n

  1. n

    S.K. Godasu, D. Varun, Narmada Valla Keerthi, P. Deepika, N. Vijaya Rekha

    n

  2. [/foreach]

n

    [foreach 286] [if 1175 not_equal=””]n t

  1. Associate Professor, Professor,Department of Pharmacy, Sri Indu institute of Pharmacy, Sheriguda, Department of Pharmacy, Sri Indu Institute of Pharmacy, Sheriguda,Telangana, Telangana,India, India
  2. n[/if 1175][/foreach]

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Abstract

nThe Bilayered tablets consisting of Trimetazidine SR as well as Clopidogrel IR were efficiently prepared by damp granulation technique as well as straight compression approach specifically. The prepared powdered mix (SR) were also preserved the physiochemical residential or commercial properties of tablet computers such as thickness, firmness, weight variant, friability and drug material. The enhanced formula consists of the average thickness of 3.1 ± 0.034, average firmness of 4.2 ± 0.42, typical weight of 100 ± 1.06, friability of 0.417 and also 99.62% of medication content. The ready powdered blend (IR) were additionally preserved the physiochemical residential or commercial properties of tablets such as thickness, hardness, weight variation, friability and medication material. The optimized solution contains the average thickness of 2.7 ± 0.034, average hardness of 4.9 ± 0.42, average weight of 251 ± 0.96, friability of 0.408 and also 99.42% of medication content. Total it may be summed up that the tablet computer having bilayer Clopidogrel and also Trimetazidine will be a fantastic as well as reliable solution in dealing with subjects with the heart problem.n

n

n

Keywords: Trimetazidine, clopidogrel, Bilayered tablets, HPMC, CSD

n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)]

n[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)] [/if 424]

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[/if 379]n

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References

n[if 1104 equals=””]

1. SC Sweetman. Martindale, The comperhensive drug reference. Pharmaceutical Press; 36th Revised edition (March 16, 2009).
2. Wikipedia. Trimetazidine. 10 August 2021. Available online at: https://en.wikipedia.org/wiki/Trimetazidine.
3. G Fragasso, et al. Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure. Eur Heart J. 2006 Apr;27(8):942-8.
4. A Onay-Besikci; S Guner, et al. The effects of chronic trimetazidine treatment on mechanical function and fatty acid oxidation in diabetic rat hearts. Can J Physiol Pharmacol, 2007, 85(5), 527-35.
5. H Darius; T Münzel; K Huber; E Sultan; U Walter. Clopidogrel Salts -Pharmacokinetic, Pharmakodynamic and Clinical Aspects. Austrian Journal of Cardiology, 2009, 16(11-12), 412- 416.
6. L Hong–Qing; Z Shi –Yang, China National knowledge infrastructure (CNKI) journal, 2010, 21(4), 30-35.
7. Nuntakan S, Phensri T as well as Kaisri U. Transdermal Circulation of Zidovudine (AZT): The Effects of Vehicles, Boosters, and also Polymer Membranes on Permeation throughout Body Pig Skin. AAPS Pharm Sci Innovation 2004; 5(3):1-8.
8. Lachmann as well as Liebermann. The Theory as well as also Approach of Industrial Drug Store. CBS; 4th edition (1 January 2020).
9. Ansel. Drug Dosage forms. Medication shipment systems. Sixth variation, Pages. 196-203.
10. Herbert A. Liebermann. Medicine Dose kinds– Tablet computer computers – Vol.1, Marcel Dekker magazines, 2nd variation, Pages. 179-181.

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  1. [if 1106 equals=””], [/if 1106][if 1106 not_equal=””],[/if 1106]
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n[/if 1114]”},{“box”:2,”content”:”

Regular Issue Open Access Article

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Research & Reviews: A Journal of Drug Formulation, Development and Production

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[if 344 not_equal=””]ISSN: 2394-1944[/if 344]

n

n

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Volume 8
Issue 3
Received October 16, 2021
Accepted October 20, 2021
Published November 1, 2021

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Editor

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Reviewer

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n”},{“box”:6,”content”:”“}]

Read More