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nTinospora Cordifolia plant is a deciduous shrub, sometimes grown as an ornamental, and stem cuttings are a simple way to propagate it. It thrives in practically every type of soil and under a variety of environmental conditions. It has been particularly trained to grow on the Neem tree, and as a result, it is said to have greater therapeutic value.n

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1. http://localhost:4001/e-nighantu/bhavaprakashanighantu/?mod=read; Guduchyadi varga; 1-4
2. Agnivesha, Charaka samhita, elaborated by Charak and Dradhbala with Ayurveddeepika commentary by Shri Chakrapanidutta, Edited by: Vaidya Yadavji trikamji acharya, Prolouged by: Prof. R.H.Shingh Published by: Chaukhambha Subharati Prakashan Reprinted 2011
3. Sushruta, V., Sushruta, A., Nagarjuna, C. and Samhita, S., 2008. With commentary Nibandhsangraha of Dalhanacharya, edited by Acharya yadavaji trikamji, Sutrasthana 38/6, 22, 31, 33, 54. Reprint, Chaukhambha surbharti Prakashan, Varanasi, pp. 164–68.
4. Vagabhat, A.H., 2010. With Sarvangsudara vyakhya of Arunadatta and Ayurveda Rasayana of Hemadri, edited by Hari Sadashiva shashtri Paradakara. Reprint, Chaukhambha Prakshana, Varanasi.
5. Bhela Samhita; Girijadaya Shukla, chowkambha Press, Varanasi.
6. Harit. Harit Samhita. Pt. Hariprasad Tripathi editor. Reprinted ed. Harit Chikitsa Sthana chapter no.2, verse no-71 to Harit Samita chapter no.58, verse no.11.Varanasi: Chaukhamba Krishanadas academy; 2009
7. Sharangdhara, Sharangdhar Samhita;With commentaries Aadhamalla and Kasiramas Gudarth Dipika,edited by Pt. Parashuram Shastri Vidyasagar, Reprint Edition 2006, Chaukhamnha Surbharati Prakashana,Varanasi, 2006
8. Acharya Vahata, Astanga Nighantu, Varunadi gana, e-nighantu.
9. Anonymous, Dhanvantari Nighantu, edited by Prof. Priyavrat sharma, reprint Edition; 2012, Chaukhambha Orientalia, Varanasi; 16–17.
10. Madanapala, A. and Nighantu, M., 2009. Pandit Hariharprasad Trivedi. Varanasi: Chaukhambha Krishnadas Academy.
11. Acharya Kaideva, Kaiyadeva Nighantu, Aushadhi varga/20, edited by Prof. Priyavrat Sharma Chaukhambha Orientalia,reprinted edition,2013, Varanasi; 5
12. Narhari pandita, Raja Nighantu, edited by Dr. Indradeva Tripathi, 5th Edition,2010; Chowkhambha Krishnadas Academy, Varanasi, 2066; 31

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nObjective: To carry out pharmacognostical and phytochemical studies on each part of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: The root, leaf, stem, flower and fruits of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, elemental analysis, and preliminary phytochemical studies. Results: The study showed microscopic and phytochemical properties which will help in identification and standardisation of Adhahapushpi (Trichodesma Indicum Linn. R. Br.). Conclusion: The study discloses precise identifying characteristics for the crude drug which will be of substantial use in identification and prevention of adulteration of the raw drug and can help as a reference for any further investigations.n

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1. Kirtikar KK, Basu BD. Indian Medicinal plants. Deharadun: International book distributors; 2005; 1693.
2. Tirky A. Ethno medicinal investigation on plants of district Raigarh (Madhya Pradesh). Ph.D thesis submitted to Barkarullah University, Bhopal (MP) India. 2002.
3. Alarmal Mangai S, Ravi Subban. In vitro cyto toxicity of Trichodesma indium Linn. R. Br., Extracts against three human Cancer Cell Lines. Asian J Pharm Clin Res. 2014; 7(3): 103–105.
4. https://www.who.int>mediacentre>factsheets
5. Johansen DA. Plant micro technique. New York and London: Mcgraw-hill book company, Inc.; 1940; 68.
6. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.6.
7. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.7.
8. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.8.
9. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.9.
10. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.10.
11. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.3.
12. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.4.
13. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.5.
14. Anonymous. Indian Pharmacopoeia. Vol-I. New Delhi: Ministry of Health and Family welfare, Govt of India, Controller of Publications; 2007; A-2.9.
15. Lavekar GS. Laboratory guide for the analysis of Ayurveda and siddha Formulations. New Delhi: CCRAS, Dept. of Ayush, Ministry of health and family Welfare, Govt. of India; 2010.
16. Lavekar GS. Laboratory guide for the analysis of Ayurveda and siddha Formulations. New Delhi: CCRAS, Dept. of Ayush, Ministry of health and family welfare, Govt. of India; 2010.
17. Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. In Phytochemical Investigations. 26th Edn. Pune, Mumbai: Nirali Prakashan; 2004; 105–109.
18. Santosh MK, Sharanabasappa GK, Shaila D, Seetharam YN, Sanjeevarao I. Phytochemical studies on Bauhinia racemosa, Bauhinia purpurea Linn. and Hardwickia binate Roxb. E-J Chem. 2007; 4(1): 21–31.
19. Esther Lydia, Sheila John, Riyazudin Mohammed, Thiyagarajan Sivapriya. Investigation on the Phytochemicals present in the Fruit peel of Carica papaya and evaluation of its Antioxidant and Antimicrobial property. Res J Pharmacognosy and Phytochem. 2016; 8(4): 217–222.
20. Thenmozhi A, Mahadeva Rao US. Secondary Metabolite screening, Bioactive compound extraction, and Disrupting Mitotic Activity of Wild Cabbage [Brassicaceae] towards Cancer Management. Asian Journal of Pharmaceutical Research. 2012; 2(1): 19–31.
21. Hosu A, Cristea V, Cimpoiu C. Analysis of total phenolic, flavonoids, anthocyanins and tannins content in Romanian red wines: Prediction of antioxidant activities and classification of wines using artificial neural networks. Food Chem. 2014; 150: 113–8.
22. Rajasekhar Pinnamaneni. Preliminary Phytochemical Investigation of peel of Pomegranate Punica granatum L. Research J Pharm Tech. 2018; 11(8): 3609–3613.
23. Chung KT, Wong TY, Wei CI, Huang YW, Lin Y. Tannins and human health: a review. Crit Rev Food Sci Nutr. 1998; 38(6): 421–64.
24. Malu SP, Obochi GO, Edem CA, Nyong BE. Effect of methods of extraction on phytochemical Constituents and antibacterial properties of Tetracarpidiumconophorum seeds. Global J Pure Appl Sci. 2009; 15(3–4): 373–6.
25. Rupasinghe HP, Jackson CJ, Poysa V, di Bierado C, Bewley JD, Jenkinson J. Soyasapogenol A and B distribution in Glycine max in relation to seed physiology, genetic variability and growing location. J Agric Food Chem. 2003; 51(20): 5888–94.
26. Choubey S, Varughese L, Kumar V, Beniwal V. Medicinal importance of gallic acid and its ester derivatives: a patent review. Pharm Pat Anal. 2015; 4(4): 305–15.

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nKatigraha is a Vataja Nanatmaja Vyadhi and it is explained as a condition characterized by Shula and restricted movements of Kati caused by Shuddha or Sama Vayu. Basti is considered as supreme therapy for Vatavyadhis. Matrabasti has dual action both Shodhana as well as Brimhana effect. In classics, no references are available for Ajamodakataila. So, it is considered as Anubhuta yoga and in the present study two ingredients are considered for the preparation of Ajamodakataila. One is Ajamoda and the other is Eranda taila, which is taken as the base for this taila. Both the ingredients of Ajamodakataila are having Vata Kapha hara property. A total of 15 patients received Ajamodakataila Matrabasti and showed 74.81% result with high significance in decreasing pain, stiffness, tenderness, improving range of movements and walking ability.n

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1. Pandit Parashurama Shastri Vidyasagar (ed.). Sharangadhara Samhita Deepika Commentory by Adamalla on Prathama Khanda, Chapter 7, Sloka No.105, 3rd edition. Varanasi, India: Chawkambha Orientalia; 1983. 103p.
2. Prof. Hariharaprasead Pandeya (ed.). Bhavaprakasha with Vidyothini Hindi Commentary of Brahmasankara Misra, 2nd volume, chapter 26, sloka no 53, edition 6th. Varanasi, India: Chaukamba Sanskrit Sansthan; 1997. 286p.
3. Vaidya Shodala (ed.). GadaNigraha, Hindi translation by Ganasahaypandey, 2nd volume, chapter 19, sloka no 160. Varanasi, India: Choukambha Surabharathy Prakasana; 2005. 505p.
4. Prof. K R Srikantha Murthy (ed.). Susruta Samhita English translation, 2nd volume, chikitsasthana, chapter 4, sloka no 5–6, reprint edition 2008. Varanasi, India: Chaukamba Orientalia; 2008. 56p.
5. Sharma RK, Das VB (ed.). Charaka Samhita, Chakrapani Datta’s Ayurveda Dipika English translation, 5th volume, chikitsasthana, chapter no 28, sloka no 104. Varanasi, India: Chaukamba Sanskrit Sansthan; 2009. 52p.
6. Sharma RK, Das VB (ed.). Charaka Samhita, Chakrapani Datta’s Ayurveda Dipika English translation, 6th volume, siddhisthana, chapter no 4, sloka no 52–54. Varanasi, India: Chaukamba Sanskrit Sansthan; 2008. 247p
7. Sharma RK, Das VB (ed.). Charaka Samhita, Chakrapani Datta’s Ayurveda Dipika English translation, 1st volume, Sutrasthana, chapter no 4, sloka no 17. Varanasi, India: Chaukamba Sanskrit Sansthan; 2008. 99p
8. Vaidya LC (ed.). Bhavaprakashahindi translation, poorvakhanda, Hareethakyadivarga, sloka no 73–74, 3rd edition. Varanasi, Delhi, Madras: Mothilal Banarasidas; 1968. 116p.
9. Murthy KRS (ed.). Vagbhata’s Ashtanga Hradayam, english translation, 1st volume, Sutrasthana, chapter 5, sloka no 57–58, 6th edition 2009. Varanasi, India: Chaukamba Krishnadas Academy; 2009. 67p.
10. Acharya VYT (ed.). SusruthaSamhitha, Sanskrit translation, Chikitsastana, Chapter 35, Sloka No.18. Varanasi, India: Choukhamba Surbharati Prakashan; 2008. 526p.
11. Acharya VYT (ed.). CharakaSamhitha, Sanskrit translation, Siddhi stana, Chapter 4, Sloka No.53. Varanasi, India: Choukhamba Surbharati Prakashan; 2011. 701p.
12. Sharma PV (ed.). Susruta Samhita, English transilation and Dalhana commentary, 2nd volume, Chikitsasthana, chapter 37, sloka no 71–74, reprint edition. Varanasi, India: Chaukamba Visvabharati; 2010. 627p.
13. Tripathi B (ed.). SharagdharaSamhitha with Dipika Hindi commentary, madhyamakhanda, Chapter 9, sloka no 1–18, 3rd edition. Varanasi, India: Chaukamba Surbharthi Prakashan; 1998. 217–220p.

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Abstract

nand retort by their energy, then previous potentials become reduced. The concept of temperament is the column of Unani Medicine. This concept was firstly introduced by Hippocrates when he specified that “It is more important to know what category of person a disease has then to know that sort of disease a person has”. Galen reflected that one pair of qualities out of four possibilities was main leading to the temperamental categories that he named Sanguine, Phlegmatic, Choleric and Melancholic temperament. Temperament (Mizaj) is signified as a unbroken quality created in the compound by interface of opposite qualities of elements. The elements distribute into minute particles to safe intimate contact with one other, since the primary qualities of the elements are four i.e., heat, cold, dryness and moister. Temperament of a newly ordered body is a product of these qualities. In human body each and every atom, molecule, cell, organs, and humour, as all are prepared with a mizaj upon which their life funtions are depends.n

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1. Ali. S, et al. Concept of Temperament (Mizaj) and Its Various Dimensions. IJRAR-International Journal of Research and Analytical Reviews. ISSN 2348 –1269, PRINT ISSN 2349- 5138.MARCH 2019; 6(1), pp.176.
2. Bie, U., Ansari, M.A., Faiz, A., Ali, F. and Khan, K.Z., 2018. Temperament (Peerless key factor of Umoor-e-Badan): definitions, chemistry, and biochemistry. Journal of Emerging and Innovative Research, 5(3), pp.881-884.
3. Maseehi, A.S. Kitab Ul Miat Fit Tibb. Hyderabad Islamic Publication Society, 1963; part 1 Pp 82,98
4. Nafees, B. Kulliyate Nafeesi. Transalation And Elobration Sharah By Hakeem Kabir Ud Din New Delhi Idara Kitab Ul Shifa. 1954; Vol 1, pp.19-21.
5. Sina, I. Alcanoon Fit Tibb. English Translation of the Critical Arabic Text New Delhi Jamia Hamdard, 1993; Vol 1, pp7-13.
6. Jurjani, A. H.Z.K.S. (Urdu translation by Hadi Hassan Khan). Matba Nami Nawal Kishore, 1902; Vol 1, pp.14.
7. Antaqi, D. Tazqaratul Albab. Egypt, Matba Ata Al Zahrze,1349 Hijri; Vol 1, PP 10
8. Majoosi A.I.A. kamil Us Sana. Urdutranslation by Kantoori G.H. New Delhi Idara Kitab Ul Shifa. 2010; Pp 24,25
9. Gazrooni,S. Kulliyat E Sadeedi Urdu Translation By Molvi Syed Abid Hussain, Lucknow, Matba Munshi Nawal Kishore, 1910; pp 12-18
10. Baghdadi, I.H. Kitab Ul Mukhtarat Fit Tibb Urdu Translation Ccrum New Delhi, 2005; pp 9
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17. Urooj Bie, et al. Temperament (Peerless Key Factor of Umoor- e-Badan): Definitions, Chemistry, and Biochemistry. Journal of Emerging Technologies and Innovative Research. (ISSN-2349- 5162). March 2018; 5 (3), pp 882
18. Ahmad, S.I. Al Umoor Al Tabiyah. New Delhi: Saini Printers, 1980; Edn 1 Pp.16-18.

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nDiabetes affects millions and thus is a major public health disease among with adults aged 30+. Available treatment although helps but many develop other side effects to complicate the issue. Ayurveda offers options to manage diabetes without complications. Present study is to see the add-on effect of Ayurveda therapy among persons on modern medicines. Ayurveda D4 combination is Jamunbeej and Gudmarpatra 5 gm churna each before breakfast and dinner and Giloy and Nagarmotha, 5 gm churna each after breakfast and dinner with ongoing modern treatment (Group A) and Group B continues on modern medicines with placebo. Treatment allocation is randomized. Once qualified for inclusion, patient is allocated to Group A or to Group B. Of the 66 patients recruited, 51 completed the study. Treatment was given for 12 weeks and monitored every 15th day until 3 months. Assessments of Ayurveda parameters, such as rog bala, agnibala, dehabala, cheatsbala and daytime sleepiness scale, fatigue assessment scale was done, at baseline and 3 months. T-test and nonparametric test used to compare results. Significant improvement in subjective and objective parameters, DSS and FAS is observed in Group A than in Group B. Conclusion: Ayurveda D4 combination can be a good treatment strategy to manage diabetes Type 2 well for reasons of safely and good quality of life.n

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6. Gajera HP, Gevariya SN, Hirpara DG, et al. Antidiabetic and Antioxidant Functionality Associated with Phenolic Constituents from Fruit Parts of Indigenous Black Jamun (Syzygiumcumini L.) Landraces. J Food Sci Technol. 2017; 54(10): 3180–3191p.
7. RK Sharma, VB Dash, editor. Charaka Samhita of Charaka. Sutrasthana; Chapter 25, Verse 40. Vol. I. Reprint 2016 Edn. Varanasi: Chowkhamba Sanskrit Series; 2016; 425p.
8. Shastri K, Chaturvedi G. Charak Samhita of Agnivesha. Part-1, Sutra Sthana; Chapter-4, Verse-33. Varanasi: Chaukhambha Bharati Academy; 2005; 89p.
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11. Thakur, et al. Gymnemasylvestre: An Alternative Therapeutic Agent for Management of Diabetes. J Appl Pharm Sci. 2012; 2(12): 001–006p.
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25. Shastri K, Chaturvedi G. Charak Samhita of Agnivesha. Part-1, Sutra Sathana; Chapter-26. Varanasi: Chaukhambha Bharati Acadamy; 2013; 507p.

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