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Aishwarya D. Jagtap,
S. K. Mohite,
- Assistant Professor, Department of Microbiology, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth “Deemed to be University”, Taluka-Karad, Dist-Satara, Maharashtra, India
- Principal, Department of Microbiology, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India
Abstract
Looking at the aspects of periodontal disease, traumatic injury, congenital defects, and the preparation of implant sites, the deficiency of dental bone, and its reconstruction, which has been simplified by many by oral and maxillofacial surgery, has proven to be a very hard and tedious task. There are many solutions which are clinically accepted, as the use of auto, allo, and xenografts, very common practices in surgery, but they come with the heavy burden of donor area morbidity, lack of immune tolerance, disease transmission, risk of infection, and lack of availability. This is where the biomaterials research strives to create novel biomaterials to develop bone tissue scaffolds as they offer the constructional support required in tissue engineering and new bone formation. There is a lot of recognition towards the added polymer to ceramic scaffolds as they are proven to be bioactive and flexible at the same time which is a very rare combination to find. Bioactive ceramics of hydroxyapatite, tricalcium phosphate, and bioactive glass used in combination with polymeric matrices and natural collagen, polylactic acid, chitosan, and polycaprolactone have shown very promising results. These, in turn, form composite scaffolds which are able to mimic the bone’s hierarchical structure, strength, and mechanical stability along with the signal required for osteogensis and vascularization. 3D printing, freeze drying and electrospinning are compositions of advanced fabrication which help the researchers in controlling the mentioned parameters and are able to develop the required surface of the scaffold, porosity, architecture, and modification to aid the adhesion of the scaffold and tissue.
Keywords: Polymer-ceramic scaffolds; Dental bone regeneration; Biomaterials; Tissue engineering; Osteoconductivity; Biodegradable polymers; Hydroxyapatite; Tricalcium phosphate; Bioactive glass; 3D printing.
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Journal of Polymer & Composites
| Volume | 14 | |
| 04 | ||
| Received | 29/07/2026 | |
| Accepted | 13/08/2026 | |
| Published | 02/09/2026 | |
| Publication Time | 35 Days |