Bhuvi,
Nitish Kumar Raghav,
- Student, St. Joseph Boy’s School, Defence Colony, Jalandhar, Punjab. India, Punjab, India
- Assistant Professor, Department of Pharmaceutical Sciences, DAV University, Jalandhar, Punjab. India, Punjab, India
Abstract
The exponential increase in global digital information has created a pressing need for storage technologies that are more durable, compact, and sustainable than conventional electronic media. While hard drives, solid-state drives, and cloud-based systems have transformed information management, they face severe limitations related to storage density, energy consumption, maintenance costs, and long-term preservation. Researchers have, therefore, begun exploring biological systems as alternative information storage platforms. Among these, bacteria have emerged as particularly promising candidates because of their ability to naturally store, replicate, and transfer genetic information through DNA. This review examines the conceptual framework of bacterial data storage, the fundamental scientific principles underlying DNA-based information encoding, recent breakthroughs in synthetic biology, and the advantages and limitations of living storage systems. Furthermore, we evaluate the expanding architecture of molecular networks, error–correction mechanisms, and the prospective deployment of engineered microorganisms for long-term archival storage. By integrating state-of-the-art computational algorithms with molecular biology, synthetic data sequences can be embedded into plasmids or genomic loci without disrupting cellular viability. Ultimately, this article highlights how bacteria may contribute to the development of next-generation archival storage technologies, bridging the gap between biological efficiency and digital infrastructure. Through a systematic evaluation of current bottlenecks, such as retrieval latency and mutation rates, we outline the trajectory required to bring this biological computing paradigm to commercial scalability.
Keywords: Bacteria, DNA, biological storage, preservation, plasmids, bioinformatics
[This article belongs to International Journal of Molecular Biotechnological Research ]
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International Journal of Molecular Biotechnological Research
| Volume | 04 | |
| Issue | 02 | |
| Received | 09/06/2026 | |
| Accepted | 12/06/2026 | |
| Published | 20/06/2026 | |
| Publication Time | 11 Days |