This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.
A Sabari Vani,
Sheeba Santhosh,
Geetha Prahalad,
M Ram Prasad Reddy,
- Assistant Professor, Department of Biomedical Engineering, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India
- Associate Professor, Department of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, Tamil Nadu, India
- Professor, Department of Electronics and Communication Engineering, Mohan Babu University (Erstwhile Sree Vidyanikethan Engineering College), Tirupati, Andhra Pradesh, India
- Professor, Department of Electrical and Electronics Engineering, Aditya College of Engineering, Madanapalle, Andhra Pradesh, India
Abstract
Polymer-based wearable biosensors have emerged as a promising technology for continuous health monitoring due to their mechanical flexibility, biocompatibility, and suitability for long-term physiological interfacing. However, prolonged exposure to biofluids, environmental variability, and mechanical deformation introduces signal drift, which significantly degrades measurement accuracy and limits clinical reliability. This paper presents a data-driven methodology for compensating signal drift in polymer-based wearable biosensors using adaptive signal processing and machine learning techniques. The proposed framework operates entirely at the software level, enabling continuous drift correction without requiring periodic physical recalibration. Wearable health monitoring datasets are employed to model realistic non-stationary signal behavior, and drift is treated as a structured, learnable component rather than random noise. Experimental evaluation demonstrates substantial reduction in baseline shift and drift rate, along with significant improvements in root mean square error and signal-to-noise ratio. The results confirm that the proposed approach enhances long-term signal stability while preserving physiological information, making it suitable for real-time wearable health monitoring applications.
Keywords: Polymer-based wearable biosensors; Signal drift compensation; Wearable health monitoring; Machine learning; Biomedical signal processing.
A Sabari Vani, Sheeba Santhosh, Geetha Prahalad, M Ram Prasad Reddy. Adaptive Drift Correction in Polymer-Based Wearable Biosensors via Data-Driven Signal Modeling. Journal of Polymer & Composites. 2026; 14(03):-.
A Sabari Vani, Sheeba Santhosh, Geetha Prahalad, M Ram Prasad Reddy. Adaptive Drift Correction in Polymer-Based Wearable Biosensors via Data-Driven Signal Modeling. Journal of Polymer & Composites. 2026; 14(03):-. Available from: https://journals.stmjournals.com/jopc/article=2026/view=243053
References
- Kurul, D. Aydoğan, S. Janat, I. A. Kırlangıç, H. O. Kaya and S. N. Topkaya, “Wearable sensors for health monitoring: Current applications, trends, and future directions,” Biosensors and Bioelectronics: X, vol. 100727, 2025. doi:10.1016/j.biosx.2025.100727.
- S. Rapuano, A. T. Smith, and J. P. Wang, “On-line drift compensation for continuous monitoring with arrays of cross-sensitive chemical sensors,” Sensors and Actuators B: Chemical, vol. 366, p. 132080, 2022. doi: 10.1016/j.snb.2022.132080.
- S. Rapuano, A. T. Smith and J. P. Wang, “On-line drift compensation for continuous monitoring with arrays of cross-sensitive chemical sensors,” Sensors and Actuators B: Chemical, vol. 366, p. 132080, 2022. doi:10.1016/j.snb.2022.132080.
- Demirci Uzun, “Machine learning-based prediction and interpretation of electrochemical biosensor responses: a comprehensive framework,” Microchemical Journal, vol. 218, p. 115656, 2025. doi: 10.1016/j.microc.2025.115656.
- Schaller, M. Kruse, A. Ortega, M. Lindauer, and B. Rosenhahn, “AutoML for multi-class anomaly compensation of sensor drift,” arXiv preprint, arXiv:2502.XXXXX, 2025.
- Mu, Y. Zhang, Z. Yan, Q. Yu, and Q. Wang, “Recent advancements in wearable sensors: integration with machine learning for human–machine interaction,” RSC Advances, vol. 15, no. 10, pp. 7844–7854, 2025. doi: 10.1039/d5ra00167f.
- M. Khaleque, M. I. Hossain, M. R. Ali, M. S. Bacchu, M. A. Saad Aly and M. Z. H. Khan, “Nanostructured wearable electrochemical and biosensor towards healthcare management: a review,” RSC Advances, vol. 13, pp. 22973–22997, 2023. doi:10.1039/D3RA03440B.
- Demirci Uzun, “Machine learning-based prediction and interpretation of electrochemical biosensor responses: a comprehensive framework,” Microchemical Journal, vol. 218, p. 115656, 2025. doi:10.1016/j.microc.2025.115656.
- Schaller, M. Kruse, A. Ortega, M. Lindauer and B. Rosenhahn, “AutoML for multi-class anomaly compensation of sensor drift,” arXiv preprint, 2025.
- N. Sunstrum, J. U. Khan, N. Wun Li and A. W. Welsh, “Wearable textile sensors for continuous glucose monitoring,” Biosensors and Bioelectronics, vol. 273, p. 117133, 2025. doi:10.1016/j.bios.2025.117133.
- Mu, Y. Zhang, Z. Yan, Q. Yu and Q. Wang, “Recent advancements in wearable sensors: integration with machine learning for human–machine interaction,” RSC Advances, vol. 15, no. 10, pp. 7844–7854, 2025. doi:10.1039/d5ra00167f.
- A. Khaleque and M. Z. H. Khan, “Capacitive spectroscopy as transduction mechanism for wearable biosensors: opportunities and challenges,” Analytical and Bioanalytical Chemistry, vol. 416, pp. 2089–2095, 2024. doi:10.1007/s00216-023-05066-y.
- “Wearable sensors data for mental health prediction,” Kaggle Dataset, 2025. Available: https://www.kaggle.com/datasets/programmer3/wearable-sensor-data-for-mental-health-prediction.
- Mohandass G, Krishnan GH, Sridhathan C, et al. Lung cancer classification using optimized attention-based CNN with DenseNet-201 transfer learning on CT. Biomed Signal Process Control. 2024;95:106351. doi:10.1016/j.bspc.2024.106351.
- Krishnan GH, Umashankar G, Abraham S. Cerebrovascular disorder diagnosis using MR angiography. Biomed Res (India). 2016;27(3):773-775.
- Mohandass G, Natarajan RA, Krishnan GH. Comparative analysis of optical coherence tomography retinal images using multidimensional and cluster methods. Biomed Res (India). 2015;26(2):273-285.
- Sabarivani A, Krishnan GH. Home health assistive system for critical care patients. Res J Pharm Biol Chem Sci. 2015;6(2):629-633.
- Santhosh S, Juliet AV, Krishnan GH. Predictive analysis of identification and disease condition monitoring using bioimpedance data. J Ambient Intell Humaniz Comput. 2021;12(2):2955-2963. doi:10.1007/s12652-020-01988-3.

Journal of Polymer & Composites
| Volume | 14 |
| 03 | |
| Received | 28/02/2026 |
| Accepted | 13/03/2026 |
| Published | 06/05/2026 |
| Publication Time | 67 Days |
Login
PlumX Metrics