Nanotechnology meet phytomedicine towards smarter drug delivery system.

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This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.

Year : 2026 | Volume : 3 | 01 | Page :
    By

    Prof. (Dr)Mohd. Wasiullah,

  • Prof. (Dr) Piyush Yadav,

  • Amit Kannaujiya,

  1. Principal, Department of Pharmacy, Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India.
  2. Head, Department of Pharma, Chemistry, Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India
  3. Scholar, Department ofPharmacy, Prasad Institute of Technology, Jaunpur, Uttar Pradesh, India

Abstract

Using bioactive substances derived from plants, or phytomedicine, has long shown promise in treating a variety of illnesses with fewer adverse effects than synthetic medications. Nevertheless, a lot of phytochemicals have issues with inadequate targeting in vivo, low bioavailability, poor solubility, and chemical instability. By enabling encapsulation, controlled release, targeted delivery, and stimuli responsive behavior, nanotechnology provides effective tools to get around these restrictions. This review examines the intersection of nanotechnology and phytomedicine, providing an overview of recent developments in nanocarrier systems, including micelles, lipid-based nanoparticles, polymeric nanoparticles, nanoemulsions, and hybrid materials, intended for the intelligent delivery of therapeutic agents derived from plants. We look at how these nano-formulations reduce off-target effects, improve pharmacokinetics, increase therapeutic efficacy, and enable controlled or triggerable release in response to environmental ues (pH, redox, enzymes, etc.). We also discuss important issues like cost, regulatory barriers, manufacturing scalability, and safety/toxicity. Lastly, we point out potential future paths that could result in the next generation of intelligent phytomedicine delivery systems, such as theranostics, green synthesis, and AI-guided design.

Keywords: phytomedicine, bioavailability, Nanotechnology, Nanoemulsions, Nanocarrier .

How to cite this article:
Prof. (Dr)Mohd. Wasiullah, Prof. (Dr) Piyush Yadav, Amit Kannaujiya. Nanotechnology meet phytomedicine towards smarter drug delivery system.. International Journal of Toxins and Toxics. 2026; 03(01):-.
How to cite this URL:
Prof. (Dr)Mohd. Wasiullah, Prof. (Dr) Piyush Yadav, Amit Kannaujiya. Nanotechnology meet phytomedicine towards smarter drug delivery system.. International Journal of Toxins and Toxics. 2026; 03(01):-. Available from: https://journals.stmjournals.com/ijtt/article=2026/view=236727


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Ahead of Print Subscription Review Article
Volume 03
01
Received 08/01/2026
Accepted 21/01/2026
Published 25/01/2026
Publication Time 17 Days
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