MOLECULAR DOCKING OF ABROMA AUGUSTA PHYTOCOMPOUNDS AGAINST ESTROGEN RECEPTOR ALPHA (ER-α) FOR THE TREATMENT OF MENSTRUAL DISORDERS

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Open Access

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Notice

nThis is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.n

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Year : 2025 [if 2224 equals=””]04/10/2025 at 9:43 AM[/if 2224] | [if 1553 equals=””] Volume : 03 [else] Volume : [/if 1553] | [if 424 equals=”Regular Issue”]Issue : [/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 02 | Page :

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    By

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    Sanjana V. Rao,

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  1. Student, Department of Biotechnology, BMS College of Engineering, Bengaluru, Karnataka, India

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Abstract

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nMenstrual disorders, including dysmenorrhea (painful menstruation), amenorrhea (absence of menstruation), and irregular menstrual cycles, significantly impact women’s reproductive health and overall well-being. These conditions often arise from hormonal imbalances, inflammation, and uterine dysfunction, necessitating effective therapeutic interventions. Current treatments, such as hormonal therapies (oral contraceptives, progestin-only pills), NSAIDs, and surgical procedures (endometrial ablation, hysterectomy), provide relief but often target symptoms rather than addressing the underlying causes. Consequently, there is a growing interest in alternative plant-based therapies with gynecological benefits, with Abroma augusta emerging as a promising candidate. The objective of the study is to identify the potential phytocompounds of A. augusta and evaluate their therapeutic potential by analyzing their binding affinity with estrogen receptor alpha (ER-α) through molecular docking. By investigating the molecular interactions of these compounds, this research seeks to provide scientific validation for the traditional use of A. augusta and explore its potential as a natural therapeutic agent for menstrual disorders.nn

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Keywords: Menstrual disorders, Abroma augusta, estrogen receptor alpha (ER-α), molecular docking

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nSanjana V. Rao. [if 2584 equals=”][226 wpautop=0 striphtml=1][else]MOLECULAR DOCKING OF ABROMA AUGUSTA PHYTOCOMPOUNDS AGAINST ESTROGEN RECEPTOR ALPHA (ER-α) FOR THE TREATMENT OF MENSTRUAL DISORDERS[/if 2584]. International Journal of Molecular Biotechnological Research. 04/10/2025; 03(02):-.

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nSanjana V. Rao. [if 2584 equals=”][226 striphtml=1][else]MOLECULAR DOCKING OF ABROMA AUGUSTA PHYTOCOMPOUNDS AGAINST ESTROGEN RECEPTOR ALPHA (ER-α) FOR THE TREATMENT OF MENSTRUAL DISORDERS[/if 2584]. International Journal of Molecular Biotechnological Research. 04/10/2025; 03(02):-. Available from: https://journals.stmjournals.com/ijmbr/article=04/10/2025/view=0

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Volume 03
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 02
Received 17/05/2025
Accepted 18/06/2025
Published 04/10/2025
Retracted
Publication Time 140 Days

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