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nThis is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.n
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Ankur Saxena, Mahesh Kumar, Bhagwat Kakde, Chandramani Yadav, Mukesh Tiwari,
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- , Department of Electronics and Communication Engineering, Bharat Institute of Engineering and Technology, Hyderabad, Department of Information and Communication Technology Pandit Deendayal Energy University, Gandhinagar, Department of Electronics and Telecommunications, Sandip Institute of Technology and Research Centre, Nashik, Department of Mechanical Engineering, Marwadi University Research Center, Faculty of Engineering & Technology, Marwadi University, Rajkot, Department of Electronics & Telecommunication Engineering, Padmabhooshan Vasantdada Patil Institute of Technology, Bavdhan, Pune, Telangana, Gujarat, Maharshtra, Gujarat, Maharshtra, India, India, India, India
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Abstract
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nThe research article study explores an innovative approach for optimizing fluid pressure within microchannels using 2D integrated microcantilevers. These microcantilevers, strategically placed within the microchannel, serve as sensitive sensors to monitor fluid pressure variations. The computational simulations illustrate the effective approach to achieving improved pressure measurement for cell separation outcomes. The integrated microcantilever can determine the fluid pressure inside the microchannel, and also determine the pressure required for the cell separation in the microchannel through the microcantilever deflection. The novelty of this research is to reduce the setup size of the device for the measurement of fluid pressure in the microchannel and the ability to control the cell pressure in the microchannel for the separation of cells. The research article designed an integrated microcantilever (R-cantilever, T-cantilever, Pi-cantilever) within microchannel maximum pressure and deflection. In the study, the T-microcantilever exhibited a maximum deflection of 5.32 µm, while the Pi-microcantilever reached a maximum pressure value of 4.66 Pa for the fluid water. The R-cantilever is an integrated microchannel for measurement of the pressure of fluid inside the microchannel where the cell separation takes place. The maximum pressure optimized is 9.17 Pa where get maximum deflection is 5.1 µm of R-cantilever. The design and simulation of the integrated microcantilever structures for the microfluidic pressure sensing mechanism were conducted using the Finite Element Method (FEM) tool for biological cell separation application.nn
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Keywords: Microcantilever, Pressure, Microchannel, Microfluidic, Cell Separation, Finite element method
n[if 424 equals=”Regular Issue”][This article belongs to Journal of Polymer and Composites ]
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nAnkur Saxena, Mahesh Kumar, Bhagwat Kakde, Chandramani Yadav, Mukesh Tiwari. [if 2584 equals=”][226 wpautop=0 striphtml=1][else]Design and Analysis of Fluid Pressure in Microchannel for Healthcare Application[/if 2584]. Journal of Polymer and Composites. 17/09/2025; 13(06):-.
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nAnkur Saxena, Mahesh Kumar, Bhagwat Kakde, Chandramani Yadav, Mukesh Tiwari. [if 2584 equals=”][226 striphtml=1][else]Design and Analysis of Fluid Pressure in Microchannel for Healthcare Application[/if 2584]. Journal of Polymer and Composites. 17/09/2025; 13(06):-. Available from: https://journals.stmjournals.com/jopc/article=17/09/2025/view=0
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| Volume | 13 | |
| [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] | 06 | |
| Received | 10/06/2025 | |
| Accepted | 03/07/2025 | |
| Published | 17/09/2025 | |
| Retracted | ||
| Publication Time | 99 Days |
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