Pharmacology in Clinical and Therapeutic Settings

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Notice

nThis is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.n

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Year : 2025 [if 2224 equals=””]14/09/2025 at 3:20 PM[/if 2224] | [if 1553 equals=””] Volume : 15 [else] Volume : [/if 1553] | [if 424 equals=”Regular Issue”]Issue : [/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03 | Page :

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    V. Basil Hans,

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  1. Research Professor,, Srinivas University, Karnataka, India

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Abstract

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nPolypharmacy, which refers to the practice of taking many medications at the same time, is becoming more common among elderly populations as a result of the steadily increasing prevalence of chronic conditions. The clinical and therapeutic consequences of polypharmacy are investigated in this paper, with a particular emphasis placed on drug-drug interactions, altered pharmacokinetics, and patient safety. The physiological changes that occur with advancing age have a substantial impact on the absorption, distribution, metabolism, and excretion of drugs, which in turn increases the likelihood of adverse drug reactions (ADRs) and therapeutic failure respectively. We examine the various methods that are now being utilized for the purpose of optimizing medicine, such as deprescribing protocols, clinical decision support technologies, and personalized pharmacotherapy techniques. In addition, the article covers the role that pharmacovigilance plays in the monitoring of drug safety and provides an overview of upcoming technologies, such as pharmacogenomic testing and artificial intelligence, that are aimed at enhancing the management of medicine for elderly patients. The purpose of this review is to highlight the urgent need for focused treatments to prevent medication-related harm and enhance therapeutic outcomes in aging populations. The review places an emphasis on a patient-centered, interdisciplinary approach.nn

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Keywords: Clinical pathways, hepatic function, polypharmacy, technology-based interventions, Therapeutic Settings.

n[if 424 equals=”Regular Issue”][This article belongs to Research and Reviews: A Journal of Pharmacology ]

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[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research and Reviews: A Journal of Pharmacology (rrjop)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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How to cite this article:
nV. Basil Hans. [if 2584 equals=”][226 wpautop=0 striphtml=1][else]Pharmacology in Clinical and Therapeutic Settings[/if 2584]. Research and Reviews: A Journal of Pharmacology. 14/09/2025; 15(03):-.

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How to cite this URL:
nV. Basil Hans. [if 2584 equals=”][226 striphtml=1][else]Pharmacology in Clinical and Therapeutic Settings[/if 2584]. Research and Reviews: A Journal of Pharmacology. 14/09/2025; 15(03):-. Available from: https://journals.stmjournals.com/rrjop/article=14/09/2025/view=0

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[if 424 not_equal=””][else]Ahead of Print[/if 424] Subscription Review Article

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Volume 15
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03
Received 11/05/2025
Accepted 25/07/2025
Published 14/09/2025
Retracted
Publication Time 126 Days

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