Construction of Chalcone–Thiadiazole Derivatives with (Spectral and Anticancer)-Study

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nThis is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.n

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Year : 2025 [if 2224 equals=””]29/08/2025 at 10:39 PM[/if 2224] | [if 1553 equals=””] Volume : 12 [else] Volume : [/if 1553] | [if 424 equals=”Regular Issue”]Issue : [/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03 | Page :

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    Nagham Mahmood Aljamali, Rajaa Abdul Ameer Ghafil, Noor Saad Jaafer, Marwah Tahseen Neamah,

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  1. Professor, Assistant Professor, Lecturer, Assist. Lecturer, Department of Chemistry ,Synthetic Organic Chemistry ,College of Education, Department of Chemistry, College Education for Girls, Kufa University, Department of Chemistry, College of Education for Girls, Kufa University, Department of Chemistry, College of Education for Girls, Kufa University, , Iraq, Iraq, Iraq, Iraq

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nMost organic chemistry compounds are widely used in the manufacture of medicines and antibiotics. Due to the spread of many epidemics that develop later as a result of not using appropriate antibiotics, these infections may develop in some tissues into carcinogenic tissues. Therefore, many researchers have developed a series of pharmaceutical compounds and developed the method of their connection with cyclic compounds. A series of chalcone derivatives has been presented here in our research and thiadiazole to be tested as biological compounds. Exploring and developing medicine is one of the first priorities in human life, so scientists and researchers in this field exhaust much of their energy and time to achieve this noble goal. What is new in this regard is the attempt to find a quantitative relationship between the medical effect and the structural composition of the drug, which is of great importance in terms of discovering a new drug or developing the performance of a previously known drug., There are many spectral measurements carried out to identification the prepared Component such as (FT-IR, H-NMR, C-NMR) – spectra, besides to other characterization like: flowing of reactions via TLC- technique and measurement of melting points, all these measurements and studies proved the accuracy and correctness of the synthesis of the prepared compounds in the study, which provided decent results for characterization of formatted compounds, in addition to cancer studies for some compounds.nn

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Keywords: chalcone, imine, thiadiazole, ,Aldol reaction, anticancer.

n[if 424 equals=”Regular Issue”][This article belongs to Research and Reviews: A Journal of Pharmaceutical Science ]

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How to cite this article:
nNagham Mahmood Aljamali, Rajaa Abdul Ameer Ghafil, Noor Saad Jaafer, Marwah Tahseen Neamah. [if 2584 equals=”][226 wpautop=0 striphtml=1][else]Construction of Chalcone–Thiadiazole Derivatives with (Spectral and Anticancer)-Study[/if 2584]. Research and Reviews: A Journal of Pharmaceutical Science. 29/08/2025; 12(03):-.

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nNagham Mahmood Aljamali, Rajaa Abdul Ameer Ghafil, Noor Saad Jaafer, Marwah Tahseen Neamah. [if 2584 equals=”][226 striphtml=1][else]Construction of Chalcone–Thiadiazole Derivatives with (Spectral and Anticancer)-Study[/if 2584]. Research and Reviews: A Journal of Pharmaceutical Science. 29/08/2025; 12(03):-. Available from: https://journals.stmjournals.com/rrjops/article=29/08/2025/view=0

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Volume 12
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03
Received 02/08/2025
Accepted 25/08/2025
Published 29/08/2025
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Publication Time 27 Days

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