Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives

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nThis is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.n

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Year : 2025 [if 2224 equals=””]27/08/2025 at 9:56 PM[/if 2224] | [if 1553 equals=””] Volume : 16 [else] Volume : [/if 1553] | [if 424 equals=”Regular Issue”]Issue : [/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03 | Page :

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    Sarah Mohammed Abed Alwan, Marwah Tahseen Neamah, Nagham Mahmood Aljamali,

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  1. Lecturer, Assist. Lecturer, Professor, Chemistry Field, Holy Karbala Education Directorate, Department of Chemistry, College of Education for Girls, Kufa University, Department of Chemistry, Synthetic Organic Chemistry, Karbala, Kufa, Kufa, Iraq, Iraq, Iraq
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Abstract

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nImidazoles can be prepared by condensation between amines and various aldehydes and ketones. Imidazole derivatives are important compounds due to their broad biological activity and pharmacological properties, such as antifungal, antioxidant, cytotoxic, anti-inflammatory, analgesic, anti-YFV (yellow fever virus), anti-tuberculosis, and antimicrobial activity. In recent years, many studies have been conducted on the preparation of biological imidazole derivatives, especially derivatives linked to heterogeneous rings containing nitrogen or any other donor atom. Therefore, we prepared in this study some types of five-membered rings derived from imidazole, pyridine, and sulfonated derivatives. Then, they were studied spectroscopically to prove their formation through the appearance of active groups in the compounds and the frequencies of their bands in the diagnostic chemical spectra, which gave values that prove and confirm the purity of the prepared derivatives of pyridine. Then, the Organic Separation Behaviors were studied as additional applications for research. It is known that the imidazole or pyridine nucleus is a highly effective hybrid compound, so it has been linked with other derivatives to study its efficiency in other applications.nn

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Keywords: Imidazole, sulphone, pyridine, hetero, five membered.

n[if 424 equals=”Regular Issue”][This article belongs to Research and Reviews: A Journal of Pharmaceutical Science ]

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[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research and Reviews: A Journal of Pharmaceutical Science (rrjops)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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How to cite this article:
nSarah Mohammed Abed Alwan, Marwah Tahseen Neamah, Nagham Mahmood Aljamali. [if 2584 equals=”][226 wpautop=0 striphtml=1][else]Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives[/if 2584]. Research and Reviews: A Journal of Pharmaceutical Science. 27/08/2025; 16(03):-.

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nSarah Mohammed Abed Alwan, Marwah Tahseen Neamah, Nagham Mahmood Aljamali. [if 2584 equals=”][226 striphtml=1][else]Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives[/if 2584]. Research and Reviews: A Journal of Pharmaceutical Science. 27/08/2025; 16(03):-. Available from: https://journals.stmjournals.com/rrjops/article=27/08/2025/view=0

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Volume 16
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 03
Received 02/08/2025
Accepted 25/08/2025
Published 27/08/2025
Retracted
Publication Time 25 Days

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