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Kashinath D. Sahoo,
Vinaya Patil,
- Professor, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India
- Research Scholar, Krishna College of Physiotherapy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharshtra, India
Abstract
Polymer chemistry has significantly contributed to the evolution of biomedical materials, particularly in the development of wearable therapeutic devices. The combination of biocompatible polymers with advanced composite materials has led to the creation of flexible, durable, and patient-friendly medical support systems. These innovations have transformed healthcare by providing non-invasive and comfortable solutions for managing chronic pain and musculoskeletal disorders. Recent advancements in polymer chemistry have focused on three key areas: biodegradable polymers, which naturally break down over time, reducing environmental and medical waste; flexible polymers, which enhance patient comfort and adaptability; and stimuli-responsive polymers, which respond to external factors such as temperature, pressure, or pH changes to provide targeted therapeutic effects. These materials have proven invaluable in wearable medical devices designed to support individuals suffering from conditions like symphysis pubis dysfunction and low back pain. One of the most promising applications is the development of wearable therapeutic belts infused with smart polymeric materials. These belts provide controlled compression, heat therapy, or electrical stimulation to alleviate pain and promote healing. The synthesis and characterization of these polymers involve mechanical strength testing, biocompatibility assessments, and durability analysis to ensure long- term effectiveness. Looking ahead, next-generation polymeric materials will incorporate nanotechnology and self-regulating properties, further enhancing their therapeutic potential. As research progresses, polymer-based wearable devices will continue to revolutionize pain management and rehabilitation, offering personalized, adaptable, and highly efficient medical solutions.
Keywords: Polymer chemistry, wearable therapeutic devices, biodegradable polymers, polymer composites, stimuli-responsive materials, biomedical applications.
Kashinath D. Sahoo, Vinaya Patil. Advances in Polymer Chemistry for Biomedical Applications: A Focus on Wearable Therapeutic Devices. Journal of Polymer and Composites. 2025; 13(05):-.
Kashinath D. Sahoo, Vinaya Patil. Advances in Polymer Chemistry for Biomedical Applications: A Focus on Wearable Therapeutic Devices. Journal of Polymer and Composites. 2025; 13(05):-. Available from: https://journals.stmjournals.com/jopc/article=2025/view=0
References
- Bravo VP, Muñoz JA. Wearables and their applications for the rehabilitation of elderly people. Medical & Biological Engineering & Computing. 2022 May;60(5):1239-52.
- Islam MA, Mobarak MH, Rimon MI, Al Mahmud MZ, Ghosh J, Ahmed MM, Hossain N. Additive manufacturing in polymer research: Advances, synthesis, and applications. Polymer Testing. 2024 Feb 13:108364.
- Kirillova A, Ionov L. Shape-changing polymers for biomedical applications. Journal of Materials Chemistry B. 2019;7(10):1597-624.
- Akay S, Yaghmur A. Recent Advances in Antibacterial Coatings to Combat Orthopedic Implant-Associated Infections. Molecules. 2024 Mar 6;29(5):1172.
- Hosseini ES, Dervin S, Ganguly P, Dahiya R. Biodegradable materials for sustainable health monitoring devices. ACS applied bio materials. 2020 Dec 23;4(1):163-94.
- Ray TR, Choi J, Bandodkar AJ, Krishnan S, Gutruf P, Tian L, Ghaffari R, Rogers JA. Bio-integrated wearable systems: a comprehensive review. Chemical reviews. 2019 Jan 28;119(8):5461-533.
- Shajari S, Kuruvinashetti K, Komeili A, Sundararaj U. The emergence of AI-based wearable sensors for digital health technology: a review. Sensors. 2023 Nov 29;23(23):9498.
- Jurak M, Wiącek AE, Ładniak A, Przykaza K, Szafran K. What affects the biocompatibility of polymers? Advances in Colloid and Interface Science. 2021 Aug 1; 294:102451.
- Rana A, Khan I, Saleh TA. Advances in carbon nanostructures and nanocellulose as additives for efficient drilling fluids: trends and future perspective—a review. Energy & Fuels. 2021 Apr 12;35(9):7319-39.
- Daneshmandi L, Barajaa M, Tahmasbi Rad A, Sydlik SA, Laurencin CT. Graphene‐based biomaterials for bone regenerative engineering: a comprehensive review of the field and considerations regarding biocompatibility and biodegradation. Advanced healthcare materials. 2021 Jan;10(1):2001414.
- Hassabo AG, Elmorsy H, Gamal N, Sediek A, Saad F, Hegazy BM, Othman H. Applications of nanotechnology in the creation of smart sportswear for enhanced sports performance: Efficiency and comfort. Journal of Textiles, Coloration and Polymer Science. 2023 Jun 1;20(1):11-28.
- Ghosh M, Thirugnanam A. Nanostructured biomaterials for load-bearing applications. In Advanced Materials for Biomechanical Applications 2022 May 30 (pp. 187-202). CRC Press.
- Yarali E, Baniasadi M, Zolfagharian A, Chavoshi M, Arefi F, Hossain M, Bastola A, Ansari M, Foyouzat A, Dabbagh A, Ebrahimi M. Magneto‐/electro‐responsive polymers toward manufacturing, characterization, and biomedical/soft robotic applications. Applied Materials Today. 2022 Mar 1; 26:101306.
- Behera A, Behera A. Shape-memory materials. Advanced Materials: An Introduction to Modern Materials Science. 2022:1-42.
- Dayyoub T, Maksimkin AV, Filippova OV, Tcherdyntsev VV, Telyshev DV. Shape memory polymers as smart materials: a review. Polymers. 2022 Aug 26;14(17):3511.
- Lam Po Tang S, Stylios GK. An overview of smart technologies for clothing design and engineering. International Journal of Clothing Science and Technology. 2006 Mar 1;18(2):108-28.
- Do NH, Truong QT, Le PK, Ha AC. Recent developments in chitosan hydrogels carrying natural bioactive compounds. Carbohydrate Polymers. 2022 Oct 15; 294:119726.
- Gong S, Lu Y, Yin J, Levin A, Cheng W. Materials-driven soft wearable bioelectronics for connected healthcare. Chemical Reviews. 2024 Jan 4;124(2):455-553.
- Khan SA, Khan SB, Khan LU, Farooq A, Akhtar K, Asiri AM. Fourier transform infrared spectroscopy: fundamentals and application in functional groups and nanomaterials characterization. Handbook of materials characterization. 2018:317-44.
- Michler GH, Lebek W. Electron microscopy of polymers. Polymer Morphology: Principles, Characterization, and Processing. 2016 Apr 15:37-53.
- Chen H, Zhuo F, Zhou J, Liu Y, Zhang J, Dong S, Liu X, Elmarakbi A, Duan H, Fu Y. Advances in graphene-based flexible and wearable strain sensors. Chemical Engineering Journal. 2023 May 15; 464:142576.
- Menczel JD, Judovits L, Prime RB, Bair HE, Reading M, Swier S. Differential scanning calorimetry (DSC). Thermal analysis of polymers: Fundamentals and applications. 2009 Apr 3:7-239.
- Fazilram P, Dr Uzma Belgaumi, Dr. Nupura Vibhute, Dr. Vidya Kadashetti, Dr. Wasim Kamate, Dr. Rashmi Gangavati. Examining Connective Tissue Changes Across Various Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: A Histochemical Polymeric Investigation. Journal of Polymer and Composites. 2024; 12(03):124-137.
- Perinelli DR, Cespi M, Bonacucina G, Palmieri GF. PEGylated polylactide (PLA) and poly (lactic-co-glycolic acid)(PLGA) copolymers for the design of drug delivery systems. Journal of pharmaceutical investigation. 2019 Jul 1;49:443-58.
- Shivani S. kadam, Randhir B. Lad, Shilpa S. Ruikar, Girish R. Pathade. Evaluation of Bio-Based Polymer Composites Containing Guava Leaf Extract for Antimicrobial Functionality. Journal of Polymer and Composites. 2024; 13(01):875-880.
- Akhtar Z. Biomedical engineering (bme) and medical health science: an investigation perspective exploration. Quantum Journal of Medical and Health Sciences. 2024 Aug 1;3(3):1-24.
- Shefa FR, Sifat FH, Uddin J, Ahmad Z, Kim JM, Kibria MG. Deep Learning and IoT-Based Ankle–Foot Orthosis for Enhanced Gait Optimization. In Healthcare 2024 Nov 14 (Vol. 12, No. 22, p. 2273). MDPI.
- Liu C, Tian W, Kan C. When AI meets additive manufacturing: Challenges and emerging opportunities for human-centered products development. Journal of Manufacturing Systems. 2022 Jul 1; 64:648-56.
- Mohanty AK, Wu F, Mincheva R, Hakkarainen M, Raquez JM, Mielewski DF, Narayan R, Netravali AN, Misra M. Sustainable polymers. Nature Reviews Methods Primers. 2022 Jun 16;2(1):46.
- Sakib-Uz-Zaman C, Khondoker MA. Polymer-based additive manufacturing for orthotic and prosthetic devices: Industry outlook in Canada. Polymers. 2023 Mar 17;15(6):1506.
- Nurse CA, Wolf DN, Rodzak KM, Teater RH, Ice CC, Fine SJ, Holtzman EC, Zelik KE. Evaluating the Biomechanical Effects and Real-World Usability of a Novel Ankle Exo for Runners. Journal of Biomechanical Engineering. 2025 Mar 1;147(3).
- Tiwari N, Shaikh AA. Hybridization of carbon fiber composites with graphene nanoplatelets to enhance interfacial bonding and thermomechanical properties for shape memory applications. Polymer-Plastics Technology and Materials. 2022 Jan 22;61(2):161-75.
- Choo YJ, Chang MC. Use of machine learning in the field of prosthetics and orthotics: A systematic narrative review. Prosthetics and Orthotics International. 2023 Jun 1;47(3):226-40.
- Quintero-Quiroz C, Botero LE, Zárate-Triviño D, Acevedo-Yepes N, Escobar JS, Pérez VZ, Cruz Riano LJ. Synthesis and characterization of a silver nanoparticle-containing polymer composite with antimicrobial abilities for application in prosthetic and orthotic devices. Biomaterials research. 2020 Aug 12;24(1):13.

Journal of Polymer and Composites
| Volume | 13 |
| 05 | |
| Received | 28/02/2025 |
| Accepted | 01/06/2025 |
| Published | 23/06/2025 |
| Publication Time | 115 Days |
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