The Function of Diuretics in Current Medical Practice and Prospective Advancements

Year : 2025 | Volume : 15 | 01 | Page :
    By

    Renu Dwivedi,

  • Avi Baliyan,

  1. Assistant Professor, School of Pharmaceutical Sciences, Bahra University, Waknaghat, Himachal Pradesh, India
  2. Student, School of Pharmaceutical Sciences, Bahra University, Waknaghat, Himachal Pradesh, India

Abstract

Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions such as congestive heart failure and hypertension, as well as in some less prevalent but medically important conditions. The possible side effects of diuretics, along with their underlying causes, are also addressed. Frequent adverse effects, including hypokalemia and hyponatremia, are examined in depth, along with other electrolyte disturbances like hypomagnesemia. The role of diuretics in the management of chronic kidney disease is explored, along with updates on new guidelines in this field. A segment on diuretic misuse is included, given its growing recognition in clinical settings, emphasizing the often tragic consequences of such abuse. Additionally, research is ongoing into the use of diuretics for diagnosing certain types of renal tubular acidosis. Lastly, some of the latest strategies for diuretic treatment are discussed, often stemming from advances in molecular biology, revealing new compounds that may soon enter future medication lists.

Keywords: Diuretics, Urine concentration, Thiazide diuretics, Potassium sparing, hydrochlorothiazide.

How to cite this article:
Renu Dwivedi, Avi Baliyan. The Function of Diuretics in Current Medical Practice and Prospective Advancements. Research and Reviews: A Journal of Pharmacology. 2025; 15(01):-.
How to cite this URL:
Renu Dwivedi, Avi Baliyan. The Function of Diuretics in Current Medical Practice and Prospective Advancements. Research and Reviews: A Journal of Pharmacology. 2025; 15(01):-. Available from: https://journals.stmjournals.com/rrjop/article=2025/view=203507


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Ahead of Print Subscription Review Article
Volume 15
01
Received 18/02/2025
Accepted 10/03/2025
Published 12/03/2025
Publication Time 22 Days
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