Exploring the Traditional and Modern Uses of Calotropis Gigantea: A Review


Year : 2025 | Volume : 14 | 01 | Page : –
    By

    Patil Shraddha S.,

  • Sameer R. Shaikh,

  • Divakar R.Patil,

  • Akash S. Jain,

  • Azam Z. Shaikh,

  • Sunil P. Pawar,

  1. B. Pharm. Student, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  2. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  3. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  4. Akash S. Jain, Department of Quality Assurance, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  5. Assistant Professor, Department of Pharmaceutics, P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Maharashtra, India
  6. Principal, Department of Pharmacognosy, P.S.G.V.P. Mandal’s College of pharmacy, Shahada, Maharashtra, India

Abstract

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Calotropis gigantea, often known as C. gigantea or Sweta Arka, is indigenous to Bangladesh, India, and Thailand in South and Southeast Asia. It has therapeutic purposes. This plant features clusters of white or lavender waxy blossoms, an oval-shaped, light green leaf, and a milky stem. The beneficial properties of C. gigantea, which is commonly used in traditional medicine, especially in India, have been validated by recent scientific findings. Among their many functions, plants like C. gigantea have historically contributed significantly to the development of human culture and civilization by acting as sources of food, fuel, and medicine. C. gigantea is known as toxic in the Siddha, Unani, and Ayurvedic systems, highlighting its dual nature as a potent and hazardous herb despite its numerous health benefits and fascination with medicine.

Keywords: Calotropis gigantea, Siddha, Unani, Ayurved

How to cite this article:
Patil Shraddha S., Sameer R. Shaikh, Divakar R.Patil, Akash S. Jain, Azam Z. Shaikh, Sunil P. Pawar. Exploring the Traditional and Modern Uses of Calotropis Gigantea: A Review. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(01):-.
How to cite this URL:
Patil Shraddha S., Sameer R. Shaikh, Divakar R.Patil, Akash S. Jain, Azam Z. Shaikh, Sunil P. Pawar. Exploring the Traditional and Modern Uses of Calotropis Gigantea: A Review. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(01):-. Available from: https://journals.stmjournals.com/joayush/article=2025/view=0


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References

  1. Singh N, Gupta P, Patel AV, Pathak AK. Calotropis gigantea: A Review on its phytochemical & pharmacological profile. Int. J. of Pharmacognosy. 2014;1:1-8.
  2. Biswasroy P, Panda S, Das D, Kar DM, Ghosh G. Pharmacological investigation of Calotropis gigantea: A benevolent herb of Nature. Research Journal of Pharmacy and Technology. 2020;13(1):461-7.
  3. Kumar PS, Suresh E, Kalavathy S. Review on a potential herb Calotropis gigantea (L.) R. Br. Scholars Academic Journal of Pharmacy. 2013 Oct 2;2(2):135-43.
  4. Kumar D, Kumar S. Calotropis gigantea (L.) Dryand-A review update. Indian Journal of Research in Pharmacy and Biotechnology. 2015 May 1;3(3):218.
  5. Datta SS, Basu S, Reddy M, Gupta K, Sinha S. Comparative evaluation of the conventional tube test and column agglutination technology for ABO antibody titration in healthy individuals: a report from India. Immunohematology. 2021 Mar 1;37(1):25-32.
  6. Ranade AV, Acharya R. Arka and its botanical equivalents: A critical analysis. Ayurpharm Int J Ayur Alli Sci. 2015;4(3):60-8.
  7. Punia G. A Review on Varieties Of Arka-Calotropis Procera (Aiton) Dryand. And Calotropis gigantea (L.) Dryand. Global Journal of Research on Medicinal Plants & Indigenous Medicine. 2013 May 1;2(5):392.
  8. Deshpande S, Deshpande K, Tomar E. CALOTROPIS GIGANTEA: A PHYTOCHEMICAL POTENTIAL. World Journal of Pharmaceutical Research. 2018 Apr 12;7(11):402-9.
  9. Saif SM, Kotkar P, Khale A. Pharmacognosy, phytochemistry and Pharmacology of Calotropis procera: a review. Research Journal of Pharmacognosy and Phytochemistry. 2015;7(1):49-56.
  10. Raja RR, Kishore N, Sreenivasulu M, RasoolBee SK, Nandini S, Ooha L, Chaitanya N. Calotropis gigantea-botanical, pharmacological view. Journal of Medicinal Plants Studies. 2016;4(2):87-9.
  11. Gharge VG, Ghadge DM, Shelar PA, Yadav AV. Importance of Pharmacognostic study of medicinal plants Calotropis gigantea (Linn.): A review. Int J Pharmacognosy. 2017;4(11):363-71.
  12. Chaudhary P, Ahamad S, Khan NA. A review on medicinal utility of Calotropis procera. World journal of pharmaceutical and medical research. 2017;3(1):335-42.
  13. Meena AK, Yadav AK, Niranjan US, Singh B, Nagariya AK, Sharma K, Gaurav A, Sharma S, Rao MM. A review on Calotropis procera Linn and its ethnobotany, phytochemical, pharmacological profile. Drug Invent Today. 2010 Jan 1;2(2):185-90.
  14. Quazi S, Mathur K, Arora S, Wing P. Calotropis procera: An overview of its phytochemistry and pharmacology. Indian Journal of Drugs. 2013;1(2):63-9.
  15. Sudesh G, Bhawana G. Ethnopharmacological potential of Calotropis procera: An overview. The International Research Journal of Pharmacy. 2012 Dec 27;3(12):100-3.
  16. Alisi CS, Onyeze GO, Ojiako OA, Osuagwu CG. Evaluation of the protective potential of Chromolaena odorata Linn. extract on carbon tetrachloride-induced oxidative liver damage. International Journal of Biochemistry Research & Review. 2011 Sep 1;1(3):69.
  17. Mittal A, Ali M. Acyclic diterpenic constituents from the roots of Calotropis procera (Ait.) R. Br. Journal of Saudi Chemical Society. 2015 Jan 1;19(1):59-63.
  18. Khan MR, Marium A, Shabbir M, Saeed N, Bokhari J. Antioxidant and hepatoprotective effects of Oxalis corniculata against carbon tetrachloride (CCl4) induced injuries in rat. Afr J Pharm Pharmacol. 2012 Aug 15;6(30):2255-67.
  19. Bairagi SM, Ghule P, Gilmore R. Pharmacology of Natural Products: A recent approach on Calotropis gigantea and Calotropis procera. Ars Pharmaceutical (Internet). 2018 Mar 20;59(1):37-44.
  20. Ajboye TO, Yakubu MT, Salau AK, Oladiji AT, Akanji MA, Okogun JI. Antioxidant and drug detoxification potential of aqueous extract of Annona senegalensis leaves in carbon tetrachloride-induced hepatocellular damage. Pharmaceutical Biology. 2010 Dec 1;48(12):1361-70.
  21. Singh A, Gautam PK, Verma A, Singh V, Shivapriya PM, Shivalkar S, Sahoo AK, Samanta SK. Green synthesis of metallic nanoparticles as effective alternatives to treat antibiotics resistant bacterial infections: A review. Biotechnology Reports. 2020 Mar 1;25:e00427.
  22. Habib MR, Aziz MA, Karim MR. Inhibition of Ehrlich’s ascites carcinoma by ethyl acetate extract from the flower of Calotropis gigantea L. in mice. Journal of Applied Biomedicine. 2010 Jan 1;8(1):47-54.
  23. Rajashekara S, Shrivastava A, Sumhitha S, Kumari S. Biomedical Applications of Biogenic Zinc Oxide Nanoparticles Manufactured from Leaf Extracts of Calotropis gigantea (L.) Dryand. BioNanoScience. 2020 Sep;10:654-71.
  24. Alam MA, Habit MR, Farjana N, Khalequzzaman M, Karim MR. Insecticidal activity of root bark of Calotropis gigantea L. against Tribalism castaneum (Herbst). World Journal of Zoology. 2009; 4(2):90-5.
  25. Awasthi S, Irshad M, Das MK, Ganti SS, Rizvi MA. Anti-inflammatory activity of Calotropis gigantea and Tridax procumbens on carrageenin-induced paw edema in rats. Ethnobotanical leaflets. 2009;2009(5):2.
  26. Rajesh R, Gowda CR, Nataraju A, Dhananjaya BL, Kemparaju K, Vishwanath BS. Procoagulant activity of Calotropis gigantea latex associated with fibrin (ogen) olytic activity. Toxicon. 2005 Jul 1;46(1):84-92.
  27. Lodhi G, KUMAR SINGH HE, Pant KK, Hussain Z. Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats. Acta Pharmaceutica. 2009 Mar 1;59(1):89-96.
  28. Setty SR, Quereshi AA, Swamy AV, Patil T, Prakash T, Prabhu K, Gouda AV. Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats. Fitoterapia. 2007 Dec 1;78(7-8):451-4.
  29. Deshmukh PT, Fernandes J, Atul A, Toppo E. Wound healing activity of Calotropis gigantea root bark in rats. Journal of ethnopharmacology. 2009 Aug 17;125(1):178-81.
  30. Begum SJ, Pratibha S, Rawat JM, Venugopal D, Sahu P, Gowda A, Qureshi KA, Jaremko M. Recent advances in green synthesis, characterization, and applications of bioactive metallic nanoparticles. Pharmaceuticals. 2022 Apr 8;15(4):455.
  31. Merzaia AB, Riaz H, Rehman R, Nisar S, Azeem MW. A review of toxicity, therapeutic and biological activities of Calotropis. IJCBS. 2017;11:58-64.
  32. Kundu S. A mini review on Calotropis procera and tapping its phytochemical and pharmacological potential. The Journal of Phytopharmacology. 2021;10(4):277-80.
  33. Mushir A, Jahan N, Ahmed A. A review on phytochemical and biological properties of Calotropis gigantea (Linn.) R. Br. Discovery Phytomedicine. 2016;3(3):15.
  34. Joseph B, George J, Jeevitha MV, Charles S. Pharmacological and biological overview on Calotropis gigantean: A comprehensive review. International Research Journal of Pharmaceutical and Applied Sciences. 2013 Oct 31;3(5):219-23.
  35. Mishra P, Yadav KS, Shrivastava P. An updated Review on Phytochemistry, Pharmacological activity and Medicinal uses of Calotropis gigantea R. Br. Research Journal of Pharmacognosy and Phytochemistry. 2017;9(2):135-8.
  36. Saha D. Calotropis gigantea: Rare traditional medicinal plants in Bangladesh having high potential ethnomedicinal value. Unique J. Ayurvedic Herb. Med. 2013;1(1):1-2.
  37. Kumar G, Karthik L, Rao KV. A review on pharmacological and phytochemical profile of Calotropis gigantea Linn. Pharmacologyonline. 2011;1:1-8.
  38. Vidya C, Hiremath S, Chandraprabha MN, Antonyraj ML, Gopal IV, Jain A, Bansal K. Green synthesis of ZnO nanoparticles by Calotropis gigantea. Int J Curr Eng Technol. 2013 Apr;1(1):118-20.
  39. Rajashekara S, Shrivastava A, Sumhitha S, Kumari S. Biomedical Applications of Biogenic Zinc Oxide Nanoparticles Manufactured from Leaf Extracts of Calotropis gigantea (L.) Dryand. BioNanoScience. 2020 Sep;10:654-71.
Ahead of Print Subscription Review Article
Volume 14
01
Received 19/12/2024
Accepted 22/01/2025
Published 11/02/2025
311