Assessment of Vitamin-D Levels Among Hashimoto and Hypothyroidism disease in Iraq, A Comparative Study.

Year : 2024 | Volume : | : | Page : –
By
vector

Sarah Hasan Kadhum AL-Huchaimi,

vector

Maysoon Khudair AL-Hadrawi,

vector

Zahraa K. Taiban,

  1. Lecturer, Department of Community Health, Kufa, Technical Institute, Al-Furat Al-Awsat Technical University, Kufa, Al-Najaf, , Iraq
  2. Assistant Professor, Department of Medical Laboratory Techniques, Kufa Technical Institute, Al-Furat Al-Awsat Technical University, Kufa, Al-Najaf, , Iraq
  3. Lecturer, Department of Community Health, Kufa, Technical Institute, Al-Furat Al-Awsat Technical University, Kufa, Al-Najaf, , Iraq

Abstract document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_abs_121521’);});Edit Abstract & Keyword

The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf Governorate for the period between June 1, 2023, and January 1, 2024. Our current study included 30 pathological samples from people with Hashimoto’s disease and 30 pathological samples from people with non-immune hypothyroidism. The concentration of Vitamin D was calculated by using the VIDAS technique and materials produced by the Etoile, France company . The results showed that the percentage of women infected with both diseases was greater than that of men, and the age group between 40-49 was the most frequent in both diseases. The results also showed that vitamin D levels in patients with Hashimoto’s disease are lower than in patients with non-autoimmune hypothyroidism. The results were analyzed using the SPSS program, version 2022. We concluded from our study that thyroid diseases are more common among women compared to men, and that age is related to the disease. The level of vitamin D also plays a important role in determining the type of disease, as it has been recorded to be significantly lower in people suffering from autoimmune hypothyroidism (Hashimoto’s). Compared with patients with non-immune hypothyroidism.

Keywords: Vitamin D, Hashimoto disease, Hypothyrodism, Iraq

How to cite this article:
Sarah Hasan Kadhum AL-Huchaimi, Maysoon Khudair AL-Hadrawi, Zahraa K. Taiban. Assessment of Vitamin-D Levels Among Hashimoto and Hypothyroidism disease in Iraq, A Comparative Study.. Research & Reviews : A Journal of Life Sciences. 2024; ():-.
How to cite this URL:
Sarah Hasan Kadhum AL-Huchaimi, Maysoon Khudair AL-Hadrawi, Zahraa K. Taiban. Assessment of Vitamin-D Levels Among Hashimoto and Hypothyroidism disease in Iraq, A Comparative Study.. Research & Reviews : A Journal of Life Sciences. 2024; ():-. Available from: https://journals.stmjournals.com/rrjols/article=2024/view=0

Full Text PDF

References
document.addEventListener(‘DOMContentLoaded’,function(){frmFrontForm.scrollToID(‘frm_container_ref_121521’);});Edit

  1. Altieri, B., Muscogiuri, G., Barrea, L.,(2017).Does vitamin D play a role in autoimmune endocrine disorders? A proof of concept. Rev Endocr Metab Disord 18, 335–346 . https://doi.org/10.1007/s11154-016-9405-9.
  2. Al-Shukry AF, Al-Hadrawi KK, AL-Hadrawi MK, Abdul-Jabar ZS,(2022). Assessment of Vitamin-D Levels among Infertile Men in Iraq, A Comparative Study. The Egyptian Journal of Hospital Medicine. 89(1):4926-4929
  3. Muscogiuri, G., Tirabassi, G., Bizzaro, G.,(2015).Vitamin D and thyroid disease: to D or not to D?. Eur J Clin Nutr 69, 291–296. https://doi.org/10.1038/ejcn.2014.265
  4. Taheriniya, S., Arab, A., Hadi, A.,(2021).Vitamin D and thyroid disorders: a systematic review and Meta-analysis of observational studies. BMC Endocr Disord 21, 171 . https://doi.org/10.1186/s12902-021-00831-5
  5. Ławnicka H, Galant-Gdula A, Motylewska E, Komorowski J, Świętosławski J, Stępień H,(2017). Estimation of vitamin D status in patients with secondary and primary hypothyroidism of different etiology. Neuroendocrinol Lett. 38(8):565-74.
  6. Blomberg Jensen M, Bjerrum PJ, Jessen TE, Nielsen JE, Joensen UN, Olesen IA, Jørgensen N,(2011). Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa. Human reproduction. 26(6):1307-1317.
  7. Corbett ST, Hill O, Nangia AK,(2006). Vitamin D receptor found in human sperm. Urology. 68(6):1345-1349.
  8. Savastano S, Barrea L, Savanelli MC, Nappi F, Di Somma C, Orio F, (2017). Low vitamin D status and obesity: Role of nutritionist. Reviews in Endocrine and Metabolic Disorders. 18:215-225.
  9. ALdhalimi HK, Aldujaili NH.,(2023). A Comparative Study of Some Parameters Levels in Infertile Women. The Egyptian Journal of Hospital Medicine. 90(1):1430-1433.
  10. Erge E, Kiziltunc C, Balci SB, Atak Tel BM, Bilgin S, Duman TT, Aktas G.,(2023). A Novel Inflammatory Marker for the Diagnosis of Hashimoto’s Thyroiditis: Platelet-Count-to-Lymphocyte-Count Ratio. Diseases. 22;11(1):15. doi: 10.3390/diseases11010015. PMID: 36810529; PMCID: PMC9944872.
  11. AL-Huchaimi, S., AL-Ammar, M., & AL-Fatlawi, S., (2023). Evaluation of Some Auto-Antibody Levels in Patients with Autoimmune Thyroiditis. Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology, 15(2), 599-608. doi: 10.21608/eajbsc.325319.
  12. Jeffrey R. Garber, Rhoda H. Cobin, Hossein Gharib, James V. Hennessey,Irwin Klein, Jeffrey I. Mechanick, Rachel Pessah-Pollack,Peter A. Singer,and Kenneth A. Woeber,(2022). Clinical Practice Guidelines for Hypothyroidism in Adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Original Studies, Reviews, And Scholarly Dialog. THYROID Volume 22, Number 12, 2012 ª Mary Ann Liebert, Inc. DOI: 10.1089/thy.0205.
  13. Ahi, S., Dehdar, M.R. & Hatami, N,(2020). Vitamin D deficiency in non-autoimmune hypothyroidism: a case-control study. BMC Endocr Disord20, 41 . https://doi.org/10.1186/s12902-020-0522-9.
  14. Lebiedziński F, Lisowska KA,(2023). Impact of Vitamin D on Immunopathology of Hashimoto’s Thyroiditis: From Theory to Practice. Nutrients. 17;15(14):3174. doi: 10.3390/nu15143174. PMID: 37513592; PMCID: PMC10385100.
  15. Liu, J., Zhang, H., Su, Y. ,(2022). Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases. Cell Biosci12, 68 . https://doi.org/10.1186/s13578-022-00810-w.
  16. Babić Leko M, Jureško I, Rozić I, Pleić N, Gunjača I, Zemunik T.,(2023). Vitamin D and the Thyroid: A Critical Review of the Current Evidence. Int J Mol Sci. 10;24(4):3586. doi: 10.3390/ijms24043586. PMID: 36835005; PMCID: PMC9964959.
  17. Quynh-Lam Tran, Louise Davies,(2023).Thyroid cancer incidence differences between men and womenCurrent Opinion in Endocrine and Metabolic Research,Volume 31,ISSN 2451-9650,https://doi.org/10.1016/j.coemr.100472.
  18. Youness, A., Miquel, C. H., & Guéry, J. C. ,(2021). Escape from X chromosome inactivation and the female predominance in autoimmune diseases. International journal of molecular sciences, 22(3), 1114.‏
  19. Wise, S. K., Damask, C., Roland, L. T., Ebert, C., Levy, J. M., Lin, S., … & Xu, X., (2023). International consensus statement on allergy and rhinology: Allergic rhinitis. In International forum of allergy & rhinology (Vol. 13, No. 4, pp. 293-859).‏
  20. Angum F, Khan T, Kaler J, Siddiqui L, Hussain A,(2020). The Prevalence of Autoimmune Disorders in Women: A Narrative Review. Cureus. 13;12(5):e8094. doi: 10.7759/cureus.8094. PMID: 32542149; PMCID: PMC7292717.
  21. Stucker, S., De Angelis, J., & Kusumbe, A. P. ,(2021). Heterogeneity and dynamics of vasculature in the endocrine system during aging and disease. Frontiers in Physiology, 12, 624928.‏
  22. Thomas, R., Wang, W. & Su, DM.,(2020). Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging. Immun Ageing 17, 2 . https://doi.org/10.1186/s12979-020-0173-8.
  23. Brown EDL, Obeng-Gyasi B, Hall JE, Shekhar S.,(2023). The Thyroid Hormone Axis and Female Reproduction. International Journal of Molecular Sciences. 24(12):9815. https://doi.org/10.3390/ijms24129815.
  24. Taylor, P.N., Lansdown, A., Witczak, J.,(2023). Age-related variation in thyroid function – a narrative review highlighting important implications for research and clinical practice. Thyroid Res 16, 7 (2023). https://doi.org/10.1186/s13044-023-00149-5.
  25. Seiler, A., Fagundes, C.P., Christian, L.M. ,(2020). The Impact of Everyday Stressors on the Immune System and Health. In: Choukèr, A. (eds) Stress Challenges and Immunity in Space. Springer, Cham. https://doi.org/10.1007/978-3-030-16996-1_6.
  26. Shaymaa Sahib Abdul-Hur A, Saher M  (2024). A physiological, Histological Evaluation Study of Erythropoietin Hormone Levels and some other Biomarkers in Male Albino Rats Treated with Acetaminophen Drug and Alcoholic Extract of Malus domestica Peels., Al-Harf Journal., Vol. 21., Issue. June 2024.
  27. Kundakovic M, Rocks D.,(2022). Sex hormone fluctuation and increased female risk for depression and anxiety disorders: From clinical evidence to molecular mechanisms. Front Neuroendocrinol. 2022 Jul;66:101010. doi: 10.1016/j.yfrne.101010. Epub 2022 Jun 15. PMID: 35716803; PMCID: PMC9715398.
  28. Taha R, Abureesh S, Alghamdi S, Hassan RY, Cheikh MM, Bagabir RA, Almoallim H, Abdulkhaliq A,(2021). The Relationship Between Vitamin D and Infections Including COVID-19: Any Hopes? Int J Gen Med. 2021 Jul 24;14:3849-3870. doi: 10.2147/IJGM.S317421. PMID: 34335050; PMCID: PMC8318784.
  29. Bikle DD.,(2021) Vitamin D: Production, Metabolism and Mechanisms of Action. . In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278935.

Ahead of Print Subscription Original Research
Volume
Received 06/11/2024
Accepted 12/11/2024
Published 26/11/2024