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Mahendra Singh Rathore,
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Abstract
nContext: Depression leads to more dysfunction and stress, which could affect the patient’s life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established.
Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence among pulmonary tuberculosis patients using Morisky Scale. Settings and Design: A cross-sectional study was conducted at tertiary care hospital in Udaipur, Rajasthan. Methods and Material: A cross-sectional study was conducted in a tertiary care hospital at Udaipur, Rajasthan, between October 2021- July 2022. The cross-sectional study was performed on people with active pulmonary tuberculosis of 18 years and above who are on anti-tuberculotic medications. Results: The subjects with a mean age of 80.07±17.33 had moderately severe depression, and 52.07±17.3 had severe depression as per the PHQ-9 score. Out of 53 males, 12 were severely depressed, and out of 39 females, 13 had depression. The influence of medication adherence on tuberculosis patients with depression showed a negative correlation i,e; (R= -762). The correlation findings were found to be significant (0.01). Our results were consistent with the expected hypothesis, and finally, a substantial interaction between tuberculosis patients and depression was observed. Conclusions: We noticed a significant association between pulmonary tuberculosis and depression. Also, the study interpreted that low medication adherence to anti-tuberculosis treatment may lead to severe depression.
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Keywords: Tuberculosis, Depression, Medication Adherence, pulmonary tuberculosis, Major depressive disorder, Morisky Medication Adherence Scale, PHQ-9 Scale.
n[if 424 equals=”Regular Issue”][This article belongs to International Journal of Pathogens(ijpg)]
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| Volume | ||
| [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] | ||
| Received | June 19, 2024 | |
| Accepted | July 5, 2024 | |
| Published | July 31, 2024 |
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