This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.
Ajit Pal Singh,
Rahul Saxena,
Suyash Saxena,
- Associate Professor, Department of Medical Lab Technology, SAHS, Galgotias University, Gr. Noida,, Uttar Pradesh, India
- Professor, Department of Biochemistry, SSAHS, Sharda University, Gr. Noida,, Uttar Pradesh, India
- Associate Professor, Department of Biochemistry, SSAHS, Sharda University, Gr. Noida,, Uttar Pradesh, India
Abstract
Traditional membrane technologies have historically been used as passive separation barriers in filtration, purification, and biomedical applications. Recent progress in nanotechnology, biomaterials, bioengineering, and surface modification has revolutionised membranes into dynamic, intelligent, and multifunctional platforms that can sense, regulate, and engage with biological systems. These sophisticated functional membranes provide unparalleled prospects for precision medicine by facilitating targeted drug administration, bio sensing, tissue restoration, organ assistance, diagnostic uses, and individualised therapy strategies. Aim This assessment seeks to deliver an extensive summary of novel functional membrane platforms and their developing significance in precision healthcare and scientific advancements. Objectives The research emphasises recent advancements in intelligent, bioinspired, nanostructured, and responsive membrane systems; examines their manufacturing techniques, functional enhancements, and biomedical uses; and addresses obstacles related to scalability, biocompatibility, clinical implementation, and regulatory approval. Material A thorough examination of the latest developments in functional membrane engineering was performed, including polymeric membranes, nanocomposite membranes, biomimetic membranes, stimuli-responsive systems, antimicrobial membranes, and AI-enhanced membrane technologies. The existing literature on their use in drug delivery, bio sensing, regenerative medicine, filtration therapy, and implantable biomedical devices was assessed. Result Sophisticated functional membranes have superior selectivity, responsiveness, therapeutic efficacy, and biological compatibility relative to traditional membrane systems. The amalgamation of nanomaterials, artificial intelligence, and molecular engineering has facilitated the development of advanced platforms for individualised diagnosis and therapy. Conclusion Functional membrane technologies signify a transformative transition from conventional filtration systems to advanced biomedical platforms. Future advancements that incorporate multifunctionality, precise engineering, and translational research will expedite their clinical implementation and transform the realm of precision healthcare.
Keywords: Functional membranes; Smart membranes; Precision healthcare; Biomedical engineering; Nanomaterials; Biomimetic membranes; Drug delivery systems; Biosensors; Tissue regeneration; Intelligent biomedical platforms.
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International Journal of Membranes
| Volume | 03 | |
| 02 | ||
| Received | 03/08/2026 | |
| Accepted | 24/09/2026 | |
| Published | 04/10/2026 | |
| Publication Time | 62 Days |