A Review of Biofilm: Mechanism of Dispersal and Eradication Strategies for Medical Devices

Year : 2026 | Volume : 16 | Issue : 02 | Page : 51 56
By

Ayushi Sharma,

Anupam Singh,

  1. Student, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, Uttar Pradesh, India
  2. Professor, Department of Biotechnology, Bansal Institute of Engineering and Technology, Lucknow, Uttar Pradesh, India

Abstract

Biofilm is formed by the adhesion of different microorganisms with each other and to the surface forming a matrix-like structure. Biofilm on medical devices forms over a period which causes severe infections and is harmful to immune-suppressed patients. Therefore, removal from the medical devices is required to get rid of it. These biofilms can be removed by various methods such as scrubbing or high-pressure spraying, steam removal, and usage of chemicals or disinfectants, etc. However, it has been seen that microbial biofilms are highly resistant to these substances. Therefore, we need new methods to eradicate biofilms from the surfaces of medical devices. These ways may include the coating of different medical devices with polymers, paints, and the application of nanoparticles of different metals. Furthermore, advanced approaches – such as nanotechnology-based coatings and surface modifications – have shown promising potential for preventing microbial adhesion and biofilm formation. Nanoparticles, particularly those of silver, copper, zinc oxide, and titanium dioxide, may exhibit strong antimicrobial properties and can interfere with microbial growth and biofilm development. Polymer-based coatings can also provide a protective barrier that reduces the attachment of microorganisms to medical device surfaces. These approaches may improve the durability and safety of medical devices while reducing the risk of device-associated infections. Therefore, the development of effective, bio-compatible, and environmentally safe anti-biofilm strategies is essential for controlling persistent biofilm-associated infections and improving patient outcomes.

Keywords: Antibiotics resistance, biofilm, biofilm eradication, biofilm on medical devices, nanoparticles combating strategies

[This article belongs to Research and Reviews: A Journal of Microbiology and Virology ]

How to cite this article: Ayushi Sharma, Anupam Singh. A Review of Biofilm: Mechanism of Dispersal and Eradication Strategies for Medical Devices. Research and Reviews: A Journal of Microbiology and Virology. 2026; 16(02):51-56.
How to cite this URL: Ayushi Sharma, Anupam Singh. A Review of Biofilm: Mechanism of Dispersal and Eradication Strategies for Medical Devices. Research and Reviews: A Journal of Microbiology and Virology. 2026; 16(02):51-56. Available from: https://journals.stmjournals.com/rrjomv/article=2026/view=257056

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Regular Issue Subscription Review Article
Volume 16
Issue 02
Received 16/07/2026
Accepted 20/08/2026
Published 21/08/2026
Publication Time 36 Days

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