Formulation and Evaluation of Herbal Cream from Ethanolic Extract of Panfuti (Bryophyllum pinnatum) Leaves

Year : 2026 | Volume : 13 | 03 | Page :
By

Asmi M. Bhavsar,

Savita B. Bhil,

Javesh K. Patil,

S.P. Pawar,

  1. Student, Department of Pharmaceutics P.S.G.V.P. Mandal’s Collage of Pharmacy Shahada, Maharashtra,
  2. Student, Department of Pharmaceutics P.S.G.V.P. Mandal’s Collage of Pharmacy Shahada, Maharashtra,
  3. Associate Professor, Department of Pharmaceutics P.S.G.V.P. Mandal’s Collage of Pharmacy Shahada, Maharashtra,
  4. Principal, Department of Pharmaceutics P.S.G.V.P. Mandal’s Collage of Pharmacy Shahada, Maharashtra,

Abstract

Bryophyllum pinnatum, commonly referred to as the “miracle leaf” or “life plant,” is a succulent medicinal plant widely valued in traditional medicine. It is well known for its broad range of pharmacological activities, including wound-healing, anti-inflammatory, and antioxidant properties, making it an important species in natural and herbal therapeutics. This study aimed to formulate a topical cream incorporating Bryophyllum pinnatum extract and evaluate its physicochemical properties, stability, and potential for skin care applications. The extract was obtained through maceration using alcoholic solvent, followed by phytochemical screening, which confirmed the presence of flavonoids, alkaloids, and tannins compounds known for their beneficial effects on the skin. The cream was formulated by the water-in-oil emulsion approach, followed by evaluation of its physicochemical characteristics, including pH, viscosity, spreadability, and homogeneity. The cream was formulated by the water-in-oil emulsion approach, followed by evaluation of its physicochemical characteristics, including pH, viscosity, spreadability, and homogeneity. The cream was formulated by the water-in-oil emulsion approach, followed by evaluation of its physicochemical characteristics, including pH, viscosity, spreadability, and homogeneity.The formulation demonstrated desirable characteristics. The results indicate that Bryophyllum pinnatum cream (Formulation F2) performed better than F1 and F3. Therefore, F2 can be considered the most effective formulation. However, further studies are needed to confirm its effectiveness and safety in clinical use.

Keywords: Bryophyllum pinnatum, topical cream, wound healing, natural skincare, physicochemical evaluation.

How to cite this article: Asmi M. Bhavsar, Savita B. Bhil, Javesh K. Patil, S.P. Pawar. Formulation and Evaluation of Herbal Cream from Ethanolic Extract of Panfuti (Bryophyllum pinnatum) Leaves. Research & Reviews: A Journal of Drug Formulation, Development and Production. 2026; 13(03):-.
How to cite this URL: Asmi M. Bhavsar, Savita B. Bhil, Javesh K. Patil, S.P. Pawar. Formulation and Evaluation of Herbal Cream from Ethanolic Extract of Panfuti (Bryophyllum pinnatum) Leaves. Research & Reviews: A Journal of Drug Formulation, Development and Production. 2026; 13(03):-. Available from: https://journals.stmjournals.com/rrjodfdp/article=2026/view=255635

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Ahead of Print Subscription Original Research
Volume 13
03
Received 24/07/2026
Accepted 08/09/2026
Published 14/09/2026
Publication Time 52 Days

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