A Comparative Machine Learning Framework for Early Prediction of Liver Cancer Using Clinical Attributes

Year : 2026 | Volume : 15 | Issue : 02 | Page : 39 47
By

Diksha Goyal,

Surendra Kumar Yadav,

Shalini Sharma,

  1. Research Scholar, Department of Computer Science, JECRC University, Ramchandrapura Industrial Area, Jaipur, Rajasthan, India
  2. Professor, Department of Computer Science Engineering, JECRC University, Ramchandrapura Industrial Area, Jaipur, Rajasthan, India
  3. Research Scholar, Department of Computer Science, JECRC University, Ramchandrapura Industrial Area, Jaipur, Rajasthan, India

Abstract

One of the main causes of cancer-related death globally is liver cancer, and improving patient outcomes depends heavily on early detection. However, low contrast, noise, organ similarity, and tumor shape and size variability make it difficult to accurately identify and segment liver tumors from medical imaging. Automated liver cancer diagnosis, segmentation, and prognosis have been greatly improved by recent developments in artificial intelligence (AI), especially deep learning. This work presents a thorough, effective method for liver tumor analysis by combining knowledge from image-processing-based MRI tumor detection, CT-based deep learning segmentation models, and AI-driven diagnostic frameworks. Otsu’s thresholding for image enhancement, marker-controlled watershed and active contor models for MRI-based segmentation, and sophisticated deep networks – including U-Net variants, ResNet hybrids, and graph convolutional networks (GCN) – for CT-based liver and tumor segmentation are among the methods highlighted in this work. Notably, SLIC superpixel clustering in conjunction with GCN architecture has shown state-of-the-art performance with high Dice scores, accuracy, and robustness in noisy environments. Furthermore, new AI systems that combine clinical parameters with multi-modal imaging (CT, MRI, and US) show promise in predicting tumor characteristics and treatment response. Overall, the review emphasizes how AI-powered models outperform conventional techniques in terms of accuracy, consistency, and automation, providing a solid basis for creating dependable computer-aided systems for clinical decision support, tumor segmentation, and early liver cancer detection.

Keywords: Convolutional neural networks, graph convolutional networks, radiomics, CT, MRI, machine learning, deep learning, hepatocellular carcinoma, and liver cancer

[This article belongs to Research and Reviews: Journal of Oncology and Hematology ]

How to cite this article: Diksha Goyal, Surendra Kumar Yadav, Shalini Sharma. A Comparative Machine Learning Framework for Early Prediction of Liver Cancer Using Clinical Attributes. Research and Reviews: Journal of Oncology and Hematology. 2026; 15(02):39-47.
How to cite this URL: Diksha Goyal, Surendra Kumar Yadav, Shalini Sharma. A Comparative Machine Learning Framework for Early Prediction of Liver Cancer Using Clinical Attributes. Research and Reviews: Journal of Oncology and Hematology. 2026; 15(02):39-47. Available from: https://journals.stmjournals.com/rrjooh/article=2026/view=253688

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Regular Issue Subscription Review Article
Volume 15
Issue 02
Received 18/03/2026
Accepted 10/06/2026
Published 31/08/2026
Publication Time 166 Days


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