Fabrication, Mechanical Characterization, and Biodegradation Analysis of Polylactic-Acid-Based Composite for Medical Sutures

Year : 2026 | Volume : 14 | Special Issue 04 | Page : 7 12
By

Wasim A. Bagwan,

U. A. Deokate,

Vimalkumar A. Patel,

Sheeth Toppo,

Mukund Anant Kulkarni,

  1. Assistant Professor, Department of General Surgery, Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Satara, Maharashtra, India
  2. Principal, Department of Pharmaceutical Chemistry, Govt. College of Pharmacy, Karad, Maharashtra, India
  3. Assistant Professor, Department of Mechanical Engineering, Government Engineering College, Bharuch, Gujarat, India
  4. Assistant Professor, Department of Home Science, Kolhan University, Chaibasa, Jharkhand, India
  5. Assistant Professor, Department of Computer Application, Bharati Vidyapeeth (Deemed to be University), Institute of Management, Kolhapur, Maharashtra, India

Abstract

Wound closure is surgical aids that relieve heavily on sutures, which help maintain proper tissue alignment and support healing. The effectiveness depends on factors such as the type of wound, required mechanical strength, risk of infection, and characteristics like absorbability and thickness of the martial. The efficacy of sutures is determined by their material properties and structural characteristics, which affect their mechanical properties. The primary objective of this study was to create absorbable medical sutures using a biocompatible polymer known as polylactic acid (PLA). The surgical suture made from polylactic acid (PLA) can be absorbed by human body. Furthermore, a composite suture consisting of PLA – chitosan was also developed to better performance. The suture was created through the extrusion method and followed by the stretching process to enhance their strength and structure. In recent years, synthetic polymers – such as polylactic acid (PLA) – have gained significant attention due to their controlled biodegradability and improved mechanical performance. The PLA sutures were successfully produced, and their performance was improved by applying a chitosan. The prepared sutures demonstrated good flexibility, with the capacity to stretch before breaking, and showed a crystal significance that contributes to their strength and stability. They also exhibited better knotting and trying ability, which is very important part during surgical procedures.

Keywords: Polylactic acid (PLA), sutures, chitosan, biocompatible polymer, Differential Scanning Calorimetry (DSC).

[This article belongs to Special Issue under section in Journal of Polymer & Composites (jopc)]

How to cite this article: Wasim A. Bagwan, U. A. Deokate, Vimalkumar A. Patel, Sheeth Toppo, Mukund Anant Kulkarni. Fabrication, Mechanical Characterization, and Biodegradation Analysis of Polylactic-Acid-Based Composite for Medical Sutures. Journal of Polymer & Composites. 2026; 14(04):7-12.
How to cite this URL: Wasim A. Bagwan, U. A. Deokate, Vimalkumar A. Patel, Sheeth Toppo, Mukund Anant Kulkarni. Fabrication, Mechanical Characterization, and Biodegradation Analysis of Polylactic-Acid-Based Composite for Medical Sutures. Journal of Polymer & Composites. 2026; 14(04):7-12. Available from: https://journals.stmjournals.com/jopc/article=2026/view=246215

References

  1. Xu L, Liu Y, Zhou W, Yu D. Electrospun medical sutures for wound healing: A review. Polymers (Basel). 2022;14(9):1637.
  2. Szabelski J, Karpiński R. Short-term hydrolytic degradation of mechanical properties of absorbable surgical sutures: A comparative study. J Funct Biomater. 2024;15(9):273.
  3. D’Cunha P, Pande B, Kathalagiri MS, Moharana AK, TS D, Pinto CS. Absorbable sutures: Chronicles and applications. Int Surg J. 2022;9(7):1383–94.
  4. Ebrahimi F, Ramezani Dana H. Poly(lactic acid) (PLA) polymers: From properties to biomedical applications. Int J Polym Mater Polym Biomater. 2022;71(15):1117–30.
  5. Manickaraj K, Thirumalaisamy R, Palanisamy S, Ayrilmis N, Massoud EE, Palaniappan M, et al. Value-added utilization of agricultural wastes in biocomposite production: Characteristics and applications. Ann N Y Acad Sci. 2025;1549(1):72–91.
  6. Mastalygina EE, Aleksanyan KV. Recent approaches to the plasticization of poly(lactic acid) (PLA): A review. Polymers (Basel). 2024;16(1):87.
  7. Desai N, Rana D, Salave S, Gupta R, Patel P, Karunakaran B, et al. Chitosan: A potential biopolymer in drug delivery and biomedical applications. Pharmaceutics. 2023;15(4):1313.
  8. Alhulaybi ZA. Fabrication and characterization of poly(lactic acid)-based biopolymer for surgical sutures. ChemEngineering. 2023;7(5):98.
  9. Tatalović V, Marinković M, Perić R, Belopavlović R. Absorbable vs. non-absorbable suture: Which one gives better results? Ir J Med Sci. 2024;193(5):2341–8.
  10. Saha RN, Datta Roy M, Ghosh S. Developing uniform surgical suture size between USP/EP and textile engineering numbering system. Indian J Surg. 2025:1–7.
  11. Faris A, Khalid L, Hashim M, Yaghi S, Magde T, Bouresly W, et al. Characteristics of suture materials used in oral surgery: Systematic review. Int Dent J. 2022;72(3):278–87.
  12. Khalid GM, Billa N. Drug-eluting sutures by hot-melt extrusion: Current trends and future potentials. Materials (Basel). 2023;16(22):7245.
  13. Zhang Z, Cui S, Ma R, Ye Q, Sun J, Wang Y, et al. Melt stretching and quenching produce low-crystalline biodegradable poly(lactic acid) filled with β-form shish for highly improved mechanical toughness. Int J Biol Macromol. 2023;251:126220.
  14. Zhu Q, Liu L, Ma P. Effect of structural parameters, knotting methods, and wet state on the tensile properties of sutures for orthopedic surgery. J Ind Text. 2024;54:15280837241257928.
  15. Naser MA, Sayed AM, Abdelmoez W, El-Wakad MT, Abdo MS. Biodegradable suture development-based albumin composites for tissue engineering applications. Sci Rep. 2024;14(1):7912.
  16. Barbosa MC, Silva HN, Lopes DD, Wanderley WF, Rosendo RA, Penha ES, et al. Biodegradable chitosan sutures enhanced with N-acetyl-D-glucosamine: Comparative study with catgut sutures. Mater Res. 2024;27:e20240278.
  17. Deng X, Gould ML, Katare RG, Ali MA. Melt-extruded biocompatible surgical sutures loaded with microspheres designed for wound healing. Biomed Mater. 2024;19(5):055007.
  18. Tong M, Zhu W, Ren Y, Li K, Yang B, Zhang R, et al. Preparation of chitosan-based coating enriched with zinc oxide nanoparticles for inhibiting Alternaria alternata on tomato fruits. J Food Meas Charact. 2025;19(7):4892–907.
  19. Wu H, Guo T, Zhou F, Bu J, Yang S, Dai Z, et al. Surface coating prolongs the degradation and maintains the mechanical strength of surgical suture in vivo. Colloids Surf B Biointerfaces. 2022;209:112214.
  20. Wang M, Xiang X, Wang Y, Ren Y, Yang L, Zhang Y. Comparison of tensile properties and knot security of surgical sutures: An in vitro mechanical study. J Oral Maxillofac Surg. 2022;80(7):
    1215–22.
  21. Nambi Gowri K, Al Asad W, Majumder S, Zhao X, King MW. Ultrashort pulse laser fabrication and evaluation of innovative resorbable barbed sutures. Polymers (Basel). 2025;17(4):544.
  22. Shi Y, Li D, Hill C, Yang L, Sheerin ED, Pilliadugula R, et al. Micro and nano plastics release from a single absorbable suture into simulated body fluid. J Hazard Mater. 2024;466:133559.
Special Issue Subscription Original Research
Volume 14
Special Issue 04
Received 18/05/2026
Accepted 28/05/2026
Published 06/06/2026
Publication Time 19 Days

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