A Study on the Comparative Changes in Nutritional Status in Follow-Up of End Stage Renal Disease Patients

Year : 2026 | Volume : 16 | Issue : 01 | Page : 9 13
    By

    Prince Muzzamil,

  • Ibtisam Nazir Khan,

  1. Student, Department of Dialysis Technology, Rayat Bahra University, Khara, Punjab, India
  2. Assistant Professor, Department of Dialysis Technology, Rayat Bahra University, Khara, Punjab, India

Abstract

Dialysis Disequilibrium Syndrome (DDS) is a rare but serious neurological complication associated with hemodialysis, particularly during the initiation phase or in patients with high metabolic derangements. It is characterized by a range of neurological symptoms resulting from rapid shifts in plasma osmolality, leading to cerebral edema. Despite advancements in dialysis techniques, DDS continues to pose a clinical challenge due to its unpredictable nature and potential for severe outcomes. The present study aimed to assess the risk factors and symptoms of Dialysis Disequilibrium Syndrome among patients undergoing hemodialysis and to determine the relationship between risk factors, symptom severity, and selected demographic and clinical variables. A quantitative descriptive research design was adopted. The study was conducted in the dialysis unit, intensive care unit, and emergency department of a tertiary care hospital. A total of 60 patients undergoing hemodialysis were selected using convenience sampling. Data were collected using a structured assessment tool comprising demographic variables, clinical variables, a DDS risk assessment screen, the Modified Early Warning System (MEWS), and a clinical signs and symptoms checklist. Continuous assessment was performed during intradialysis and for one-hour post-dialysis. Descriptive and inferential statistics were used for data analysis. The results revealed that most patients exhibited a moderate risk of DDS during intradialysis and a low risk during the post-dialysis period. Mild to moderate neurological symptoms were commonly observed. A statistically significant positive correlation was found between DDS risk factors and symptom severity during intradialysis (r = 0.501, p = 0.001). Pre-existing neurological abnormalities showed a significant association with DDS risk. The study concludes that early identification of high-risk patients and continuous neurological monitoring during hemodialysis are essential to prevent severe DDS-related complications.

Keywords: Dialysis disequilibrium syndrome, hemodialysis, modified early warning system, neurological symptoms, risk factors

[This article belongs to Research and Reviews : A Journal of Life Sciences ]

How to cite this article:
Prince Muzzamil, Ibtisam Nazir Khan. A Study on the Comparative Changes in Nutritional Status in Follow-Up of End Stage Renal Disease Patients. Research and Reviews : A Journal of Life Sciences. 2026; 16(01):9-13.
How to cite this URL:
Prince Muzzamil, Ibtisam Nazir Khan. A Study on the Comparative Changes in Nutritional Status in Follow-Up of End Stage Renal Disease Patients. Research and Reviews : A Journal of Life Sciences. 2026; 16(01):9-13. Available from: https://journals.stmjournals.com/rrjols/article=2026/view=244641


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Regular Issue Subscription Original Research
Volume 16
Issue 01
Received 22/11/2025
Accepted 30/12/2025
Published 01/01/2026
Publication Time 40 Days
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