Comprehending Ancient Wisdom of Ayurveda: Unveiling Phytochemistry and Molecular Mechanisms of Rasayana Medicine

Year : 2025 | Volume : 14 | Issue : 03 | Page : 59 67
    By

    Garima Shandilya,

  • Chirag Vyas,

  • Shivaji Dinkar Jadhav,

  • Sachin Chavan,

  1. Research Scholar, Department of Nanotechnology, Bharati Vidhyapeeth deemed to be University, College of Engineering, Pune, Maharashtra, India
  2. Technical Assistant, Department of Botany, Mohanlal Sukhadiya University, Udaipur, Rajasthan, India
  3. Associate Professor, Department of Basic Science and Humanities, Bharati Vidhyapeeth deemed to be University, College of Engineering, Pun, Maharashtra, India
  4. Professor, Department of Mechanical Engineering, Bharati Vidhyapeeth deemed to be University, College of Engineering, Pune, Maharashtra, India

Abstract

Rasayana medicine is an integral part of ancient medical system of India. In Sanskrit ‘rasayana’ refers to “path of essence” and serves as one of the eight clinical specialties of classical Ayurveda. Rasayana focuses on restoring health by replenishing vital fluids of human body. According to Ayurveda, our physical body constitutes of seven dhatus called ‘Sapthdhatu’, sapth-seven and dhatu-tissues or microchannels. These channels are the pathway through which vital nutrients flows to nourish our bodies. Taking rasayana medicine is dedicated for immune protection, acts as anti-degenerative and rejuvenates health care by alleviating effects of age-related degeneration along with restoring cellular stability in disease and healthy individuals. Therefore, rasayana is a tool to create premium dhatus so when any dis-ease or dishamaony occurs, quality of dhatus promotes rejuvenation, regeneration, healing by enhancing immunity and developmental mechanisms by tuning cellular homeostasis. The phytochemistry and molecular mechanisms lay foundation for the pathways or chemical reactions that will be initiated to provide the endpoints of restoring physical and mental vitality. Rasayana phytochemistry and its molecular action are based on robust correlation between its therapeutic goals and the impact bioactive compounds provides in achieving its observed biological effects. Traditional Rasayana therapies have time-tested system approaches by bridging detoxification or disease healing aspect along with restoring balance and sustaining health. The rejuvenating out-turn of rasayanas stems from their synergistic action of numerous bioactive components which are plant-based. This review article implies understanding role on its phytochemical composition and their molecular mechanisms behind mode of action of rasayana medicine coinciding modern science outview through ayurvedic principles, thus validating its traditional claims.

Keywords: Rasayana, Ayurveda, phytochemistry, nanotechnology, nanomedicine, molecular mechanisms, cellular homeostasis

[This article belongs to Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ]

How to cite this article:
Garima Shandilya, Chirag Vyas, Shivaji Dinkar Jadhav, Sachin Chavan. Comprehending Ancient Wisdom of Ayurveda: Unveiling Phytochemistry and Molecular Mechanisms of Rasayana Medicine. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(03):59-67.
How to cite this URL:
Garima Shandilya, Chirag Vyas, Shivaji Dinkar Jadhav, Sachin Chavan. Comprehending Ancient Wisdom of Ayurveda: Unveiling Phytochemistry and Molecular Mechanisms of Rasayana Medicine. Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2025; 14(03):59-67. Available from: https://journals.stmjournals.com/joayush/article=2025/view=239420


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Regular Issue Subscription Review Article
Volume 14
Issue 03
Received 10/09/2025
Accepted 26/09/2025
Published 27/09/2025
Publication Time 17 Days
25

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