Nilesh Prakash Badgujar,
- Professor and Head, Department of Chemical Technology, SRICT, UPL University of Sustainable Technology, Ankleshwar, Gujarat, India
Abstract
Triphala Guggulu is a classical formulation widely used in Ayurveda for the management of metabolic and inflammatory disorders. It represents a synergistic combination of Triphala – composed of Emblica officinalis, Terminalia bellirica, and Terminalia chebula – along with the oleo-gum resin of Commiphora mukul. In traditional Ayurvedic practice, this formulation has been prescribed for conditions, such as arthritis, obesity, hyperlipidemia, and chronic constipation, primarily due to its reputed ability to enhance digestion, regulate lipid metabolism, and support systemic detoxification. The present review aims to compile and critically evaluate the available literature on the historical background, phytochemical composition, pharmacological activities, and therapeutic relevance of Triphala Guggulu. Phytochemical analyses indicate the presence of diverse bioactive constituents, including tannins, phenolic compounds, flavonoids, and guggulsterones, which collectively contribute to its biological activity. Experimental and preclinical studies have reported significant antioxidant, anti-inflammatory, anti-atherogenic, hypolipidemic, and hepatoprotective effects associated with this formulation. These findings provide preliminary scientific validation for its traditional therapeutic applications. Despite growing interest and increasing pharmacological evidence, several challenges remain in the scientific validation and clinical translation of Triphala Guggulu. Variability in raw materials, lack of standardized formulations, limited large-scale clinical trials, and insufficient long-term safety data restrict its broader acceptance within evidence-based healthcare systems. Therefore, further well-designed experimental studies, standardized quality control protocols, and rigorous clinical investigations are essential to substantiate its efficacy and safety. Strengthening the scientific evidence base will facilitate the rational integration of this traditional Ayurvedic formulation into contemporary integrative and complementary medicine frameworks.
Keywords: Anti-inflammatory, ayurveda, guggulsterones, polyherbal formulation, standardization, Triphala Guggulu
Nilesh Prakash Badgujar. Pain Management Through Ayurvedic Tablets and Capsules. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2026; 13(01):-.
Nilesh Prakash Badgujar. Pain Management Through Ayurvedic Tablets and Capsules. Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy. 2026; 13(01):-. Available from: https://journals.stmjournals.com/rrjoasyn/article=2026/view=238833
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| Volume | 13 |
| 01 | |
| Received | 10/02/2026 |
| Accepted | 03/03/2026 |
| Published | 05/03/2026 |
| Publication Time | 23 Days |
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