Clinical Evaluation of Efficacy of a Polyherbal Unani Formulation (Mentioned in Makhzan-Ul-Ilaj) in the Management of Warm-e-Lauzatain-Haad (Acute Tonsillitis)

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Year : 2026 | Volume : 15 | Issue : 01 | Page : 13 22
    By

    Shaikh Aqueel,

  • Mujeeb Pinjari,

  • Shaikh Ather,

  1. Assistant Professor, Department of Moalajat, IQRA Unani Medical College, Jalgaon, Maharashtra, India
  2. Assistant Professor, Department of Tahaffuzi wa Samaji Tibb, IQRA Unani Medical College, Jalgaon, Maharashtra, India
  3. PG Scholar, Department of Moalajat (Medicine), ZVM Unani Medical College, Pune, Maharashtra, India

Abstract

Background: Warm-e-Lauzatain-Haad (Acute Tonsillitis) is an inflammatory condition of the palatine tonsils characterized by throat pain, fever, odynophagia and general discomfort. It is particularly common among adolescents and young adults and contributes substantially to outpatient visits and missed academic or workdays. In Unani medicine Warm-e-Lauzatain is described as a hot inflammatory swelling arising from deranged humors, exposure to irritants or descending catarrhal matter. Classical Unani texts including Makhzan-ul-Ilaj, advocate the use of polyherbal decoctions such as Joshanda due to their anti-inflammatory, demulcent and expectorant effects. This study was designed to clinically evaluate the efficacy and safety of a traditional Polyherbal Unani formulation in the management of Warm-e-Lauzatain-Haad. Methods: An open-label, single-arm clinical study was conducted on 60 patients aged 16–25 years diagnosed with Warm-e-Lauzatain-Haad based on classical symptoms and clinical examination. The polyherbal formulation consisted of Behidana, Unnab, Sapistan, Tukhm-e-Khatmi, Tukhm-e-Khayarain, Tukhm-e-Khubbazi and Asl-us-Soos, prepared as Joshanda. Patients received 20 ml of the formulation twice daily for 12 days. Therapeutic assessment included subjective parameters throat pain, dysphagia, fever, earache and tenderness and objective parameters such as complete blood count (CBC) and erythrocyte sedimentation rate (ESR). Data were analyzed using paired t-test and Chi-square test. Results: Marked clinical improvement was observed by the end of the treatment period. Difficulty in swallowing, throat pain, fever and associated symptoms significantly decreased (p < 0.0001). ESR levels showed a significant reduction from baseline (p = 0.004), neutrophil counts declined (p = 0.003), and lymphocyte counts increased (p = 0.0039), indicating anti-inflammatory and immunomodulatory effects of the formulation. No adverse drug reactions or safety concerns were reported during the study. Conclusion: The Polyherbal Unani formulation (Joshanda) as described in Makhzan-ul-Ilaj demonstrated significant clinical efficacy in alleviating symptoms of Warm-e-Lauzatain-Haad and improving inflammatory markers. Its safety, affordability and traditional acceptance highlight its potential as an effective complementary or alternative therapeutic option for acute tonsillitis. Larger controlled trials are warranted to validate these findings

Keywords: Acute tonsillitis, Joshanda, Makhzan-ul-Ilaj, Polyherbal Unani formulation, Unani medicine, Warm-e-Lauzatain-Haad

[This article belongs to Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ]

How to cite this article:
Shaikh Aqueel, Mujeeb Pinjari, Shaikh Ather. Clinical Evaluation of Efficacy of a Polyherbal Unani Formulation (Mentioned in Makhzan-Ul-Ilaj) in the Management of Warm-e-Lauzatain-Haad (Acute Tonsillitis). Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2026; 15(01):13-22.
How to cite this URL:
Shaikh Aqueel, Mujeeb Pinjari, Shaikh Ather. Clinical Evaluation of Efficacy of a Polyherbal Unani Formulation (Mentioned in Makhzan-Ul-Ilaj) in the Management of Warm-e-Lauzatain-Haad (Acute Tonsillitis). Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy. 2026; 15(01):13-22. Available from: https://journals.stmjournals.com/joayush/article=2026/view=237738


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Regular Issue Subscription Original Research
Volume 15
Issue 01
Received 30/12/2025
Accepted 13/02/2026
Published 14/02/2026
Publication Time 46 Days
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