A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica

Year : 2026 | Volume : 14 | Issue : 01 | Page : 696 704
    By

    Chandravadhana A,

  • Nandakumar V,

  • K.B. Reema,

  • Devi A,

  • Nagaraja N,

  • K. Suresh Kumar,

  • A. Jayanthi,

  1. Associate Professor, Department of Physics, S. A. Engineering College -Autonomous Chennai, Tamil Nadu, India
  2. Associate Professor, Post Graduate Department of Physics, Maharani’s Science College for Women (Autonomous) Mysuru, Karnataka, India
  3. Associate Professor, Department of Physics, Government First Grade College Channapatna, Karnataka, India
  4. Assistant Professor, Department of Computer Science and Engineering, Sri Ramachandra Faculty of Engineering and Technology- Chennai, Tamil Nadu, India
  5. Associate Professor, Department of Physics, Government First Grade College Vijayanagar, Bengaluru, Karnataka, India
  6. Professor, Department of Physics, P. T. Lee Chengalvaraya Naicker College of Engineering and Technology, Kancheepuram, Tamil Nadu, India
  7. Professor, Department of Physics, Jeppiaar Institute of Technology, Autonomous, Sriperumbudur, Tamil Nadu, India

Abstract

Nano-silica and silica-coated nanoparticles have gained significant attention lately due to their exceptional chemical and physical properties, including a high surface area-to-volume ratio, adjustable porosity, thermal and chemical stability, biocompatibility, and ease of surface modification. These characteristics make them versatile materials applicable in various scientific and industrial sectors. Their ability to control particle size, shape, and surface traits allows them to be effectively utilized in catalysis, drug delivery, biosensing, and environmental remediation. Silica nanoparticles are particularly valued for their chemical inertness, low toxicity, and capacity for functionalization with organic or inorganic molecules, enabling the creation of multifunctional hybrid materials. Their porous structure and biocompatibility enable efficient drug carrier systems for controlled release and targeted therapies. Furthermore, silica serves as a solid support for active metal sites, enhancing catalytic efficiency and selectivity. Silica-based nanoparticles are beneficial for environmental applications, such as dye removal from polluted water, heavy metal adsorption, and contaminant degradation. Silica-coated metal nanoparticles merge the protective advantages of silica shells with the desired optical, electrical, and magnetic properties of metals, thereby enhancing the nanoparticles’ lifespan and functionality while improving dispersion and preventing agglomeration. Recent advances in synthesis techniques, such as sol-gel processes, microemulsion technologies, and surface grafting, allow for better control over the size, thickness, and efficacy of silica coatings. This review discusses the primary applications of nano-silica, recent innovations in silica-coated nanoparticle technology, and its growing potential in biomedicine, environmental sustainability, catalysis, and sensing.

Keywords: Nano-silica, silica-coated nanoparticles, biocompatibility, catalysis, biomedical applications.

[This article belongs to Journal of Polymer & Composites ]

How to cite this article:
Chandravadhana A, Nandakumar V, K.B. Reema, Devi A, Nagaraja N, K. Suresh Kumar, A. Jayanthi. A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica. Journal of Polymer & Composites. 2026; 14(01):696-704.
How to cite this URL:
Chandravadhana A, Nandakumar V, K.B. Reema, Devi A, Nagaraja N, K. Suresh Kumar, A. Jayanthi. A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica. Journal of Polymer & Composites. 2026; 14(01):696-704. Available from: https://journals.stmjournals.com/jopc/article=2026/view=236655


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References

  1. Siegel RW. Synthesis and processing of nanostructured materials. Nanostruct Mater. 1992;3(1–6):1–18. doi:10.1016/0965-9773(92)90044-X.
  2. Slowing II, Vivero-Escoto JL, Wu CW, Lin VS. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev. 2008;60(11):1278–88.
  3. Wang Y, Zhao Q, Han N, Bai L, Li J, Liu J, Che E, Hu L, Zhang Q, Jiang T, Wang S. Mesoporous silica nanoparticles in drug delivery and biomedical applications. 2015;11(2):313-27.
  4. Fatima R, Katiyar P, Kushwaha K. Recent advances in mesoporous silica nanoparticle: synthesis, drug loading, release mechanisms, and diverse applications. Front 2025; 7:1564188.
  5. Wu S, Mou C-Y, Lin H-P. Synthesis, characterization, and applications of mesoporous silica nanoparticles. Nano Today.2022; 42:101359.
  6. Iler RK. The chemistry of silica. New York: Wiley; 1979.
  7. Vallet-Regi M, Rámila A, Del Real RP, Pérez-Pariente J. A new property of MCM-41: drug delivery system. Chem Mater. 2001;13(2):308-311.
  8. Thompson EL. Development of functional materials for environmental remediation. Am J Mater Eng. 2023;4(1):1–6.
  9. Brinker, C. J., & Scherer, G. W. (1990). Sol-gel science: the physics and chemistry of sol-gel processing. Gulf Professional Publishing.
  10. Stöber, W., Fink, A., Bohn E. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Interface Sci. 1968;26(1):62–69.
  11. Pileni MP. Nanocrystals: fabrication, structure, and properties. Chem Rev.2001; 101:1359–80.
  12. Goudeli E. Multiscale design of aerosol synthesis of nanomaterials [dissertation]. Zurich (CH): ETH Zurich; 2016.
  13. Mukherjee P, Ghosh A, Das NK. Surface chemistry of functionalized silica nanomaterials. Adv Colloid Interface Sci.2019; 270:1–25.
  14. Gallas J-P, Renaudin G, et al. Physicochemical properties of functionalized silica nanoparticles. 2009; 25:5825–34.
  15. Burnett LA, Vasquez JK, Porter AE, et al. Advances in hybrid silica nanomaterials for biomedical applications. ACS Nano.2021; 15:1234–45.
  16. Guo M, Li Y, Xu H, et al. Mesoporous silica-based antibacterial nanomaterials: mechanisms and applications. J Mater Chem B. 2022; 10:1500–15.
  17. Liz-Marzán LM, Giersig M, Mulvaney P. Synthesis of nanosized gold–silica core–shell particles. 1996;12(18):4329-35.
  18. Liu S, Han MY. Silica-coated metal nanoparticles. Chem Asian J. 2010;5(1):36-45.
  19. Kobayashi Y, Matsudo H, Li TT, Shibuya K, Kubota Y, Oikawa T, et al. Fabrication of quantum dot/silica core–shell particles immobilizing Au nanoparticles and their dual imaging functions. Appl Nanoscience. 2016;6(3):301–7.
  20. Shen R, Camargo PH, Xia Y, Yang H. Silane-based poly (ethylene glycol) as a primer for surface modification of nonhydrolytically synthesized nanoparticles using the Stober method. Langmuir. 2008;24(19):11189–95. Sanchez F, Sobolev K. Nanotechnology in concrete – A review. Constr Build Mater. 2010;24(11):2060-71.
  21. Xu Z, Chen H, Li X, et al. Advanced analytical approaches for nanosilica characterization. Anal Chem. 2020;92(14):9932–9941.
  22. Cai W, Wang Y, Zhao D, et al. Optical properties and surface engineering of silica-based nanostructures. J Phys Chem C. 2021;125(5):2783–2794.
  23. Kim DJ, Park JH, Lee S, et al. Functional mesoporous silica nanomaterials for biomedical applications. Small. 2021;17(12):e2006582.
  24. Di Sia P. Nanotechnologies and advanced smart materials: the case of architecture and civil engineering. In: The ELSI Handbook of Nanotechnology: Risk, Safety, ELSI and Commercialization. p. 67–87.
  25. Qing Y, Zenan Z, Deyu K, et al. Influence of nano-SiO2 addition on properties of hardened cement paste. Mater Chem Phys. 2017;105(2-3):229-33.
  26. Slowing II, Vivero-Escoto JL, Wu CW, et al. Mesoporous silica nanoparticles for drug delivery. Adv Drug Deliv Rev. 2008;60(11):1278-88.
  27. Knopp D, Tang D, Niessner R. Bioanalytical applications of biomolecule-functionalized nanometer-sized doped silica particles. Anal ChimActa. 2009;647(1):14-30.
  28. Rai M, Deshmukh SD, Ingle AP, et al. Nanotechnology-based antimicrobials in medicine. Nanotechnol Rev. 2018;7(2):99-116.
  29. Hua M, Zhang S, Pan B, et al, Heavy metal removal from water/wastewater by nanosized metal oxides. J Hazard Mater. 2012;211-2:317-31.
  30. Zhou W, Liu H, Wang J, et al. Ag2O/SiO2/TiO2nanocomposites for enhanced photocatalytic degradation of organic dyes. Appl Surf Sci.2019; 470:439-47.
  31. Arumugam C, Kannan V, Karthikeyan V, Theja VC, Thongmee S, Chan CK, et al. Facile modification of TiO2 as S-Scheme multifunctional materials for environmental protection and energy-storage applications. Surf Interfaces.2024; 55:105298.
  32. Dhakshinamoorthy A, Asiri AM, Garcia H. Metal-organic frameworks as catalysts for organic reactions. ChemSoc Rev. 2012;41(15):5262-84.
  33. Hoffmann F, Cornelius M, Morell J, et al. Silica-based mesoporous organic–inorganic hybrid materials. AngewChemInt Ed. 2006;45(20):3216-51.
  34. Jiang L, Wu Z, Wang Y, et al. Nano-silica hybrid polyimide films for high-performance dielectric materials. Compos Sci Technol.2013; 82:52-8.
  35. Mahltig B, Haufe H, Böttcher H. Functionalization of textiles by inorganic sol-gel coatings. J Mater Chem. 2005;15(41):4385-98.
  36. Torney F, Trewyn BG, Lin VSY, et al. Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nat Nanotechnol. 2007;2(5):295-300.
  37. Siddiqui MH, Al-Whaibi MH. Role of nano-SiO2 in germination of tomato (Lycopersicumesculentum seeds Mill.). Saudi J Biol Sci. 2014;21(1):13-7.
  38. Kalteh M, Alipour ZT, Ashraf S, et al. Effect of silica nanoparticles on basil (Ocimumbasilicum) under salinity stress. J Chem Health Risks. 2018;4(3).
  39. Epstein E. The anomaly of silicon in plant biology.ProcNatlAcadSci U S A. 1994;91(1):11-7.
  40. Zhao Y, Liu J, Horn M, et al.Recent advancements in metal oxide-based electrode materials for supercapacitors.J Mater Chem A. 2020;8(17):8338-56.
  41. Saha, A., Mishra, P., Biswas, G., & Bhakta, S. “Greening the pathways: a comprehensive review of sustainable synthesis strategies for silica nanoparticles and their diverse applications.” RSC Advances, 2024, 14, 11197–11216.
  42. Mesoporous silica nanoparticles: synthesis and multifaceted functionalization for controlled drug delivery.” Journal of Drug Delivery Science and Technology, 2023, 81, 104305.
  43. Hady MA. Recent advances in ultra-porous drug nano-carriers: synthesis and targeting approaches. Silicon. 2024; 16:345–366.
  44. Ros-Lis JV, et al. A comparative life cycle assessment of the synthesis of mesoporous silica materials on a small and a large scale. Green Chem. 2024;26:10107–10114.
Regular Issue Subscription Review Article
Volume 14
Issue 01
Received 15/10/2025
Accepted 06/12/2025
Published 09/02/2026
Publication Time 117 Days
133

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