Epidemiology of Stomach Cancer in Northeastern States of India: Focusing on Nagaland and the Effectiveness of Screening Programs

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This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.

Year : 2025 | Volume : 2 | 02 | Page :
    By

    Atul KHAJURIA,

  1. Director, Desh Bhagat University, Punjab, India

Abstract

Stomach cancer represents a critical public health burden in northeastern India, with Nagaland exhibiting the highest age-standardized incidence rate in the country – nearly triple the national average. This elevated risk profile stems from multiple factors including traditional dietary practices (high consumption of smoked meats and fermented foods), widespread Helicobacter pylori infection (affecting approximately 70% of adults), prevalent tobacco/alcohol use, and limited healthcare infrastructure. Despite demonstrated success of endoscopic screening programs in nations like Japan and South Korea, such initiatives remain largely unavailable in Nagaland, creating a pressing need to examine both epidemiological patterns and screening barriers in this high-risk population.

Keywords: gastric cancer, cancer screening, cancer epidemiology, health disparities, India, Helicobacter pylori, early detection of cancer, public health

How to cite this article:
Atul KHAJURIA. Epidemiology of Stomach Cancer in Northeastern States of India: Focusing on Nagaland and the Effectiveness of Screening Programs. International Journal of Pathogens. 2025; 02(02):-.
How to cite this URL:
Atul KHAJURIA. Epidemiology of Stomach Cancer in Northeastern States of India: Focusing on Nagaland and the Effectiveness of Screening Programs. International Journal of Pathogens. 2025; 02(02):-. Available from: https://journals.stmjournals.com/ijpg/article=2025/view=234951


References

  1. National Cancer Registry Programme. (2021). Three-Year Report of Population Based Cancer Registries: 2018-2020. Indian Council of Medical Research. https://ncdirindia.org/ncrp/
  2. Nair, Suresh, Kumar, Rajesh, & Phukan, Ramesh K. (2020). Dietary patterns and gastric cancer risk in Northeast India: A case-control study. Journal of Gastrointestinal Oncology, 11(3), 456-465. https://doi.org/10.21037/jgo-20-123
  3. Phukan, Ramesh K., Narain, Kangjam, Zomawia, Eric, Hazarika, Nirmali C., & Mahanta, Jagadish. (2016). High prevalence of Helicobacter pylori infection in Northeast India: A community-based cross-sectional study. Indian Journal of Gastroenterology, 35(3), 123-130. https://doi.org/10.1007/s12664-016-0656-x
  4. Hamashima, Chisato, Shabana, Michiko, Okada, Kenji, Okamoto, Mikizo, & Osaki, Yoneatsu. (2018). Mortality reduction from gastric cancer by endoscopic and radiographic screening. Cancer Science, 109(3), 1752-1759. https://doi.org/10.1111/cas.13554
  5. Ao, Moatoshi, Angami, Kevichüsa, & Sema, Aküm. (2021). Barriers to cancer screening in Nagaland: A qualitative exploration of healthcare challenges. Asian Pacific Journal of Cancer Prevention, 22(4), 987-995. https://doi.org/10.31557/APJCP.2021.22.4.987
  6. Yamamoto, Yuji, Fujisaki, Junko, Omae, Masayo, & Hirasawa, Toshiaki. (2021). Molecular pathogenesis and genomic landscape of gastric cancer. Nature Reviews Clinical Oncology, 18(3), 165-178. https://doi.org/10.1038/s41571-020-00462-2
  7. Phukan, Ramesh K., Ali, Mohammad S., Chetia, Chitralekha K., & Mahanta, Jagadish. (2018). Early-onset gastric cancer in Northeast India: A clinicopathological study. Asian Pacific Journal of Cancer Prevention, 19(3), 747-751. https://doi.org/10.22034/APJCP.2018.19.3.747
  8. Malhotra, Rakesh K., Singh, Vineet, & Dhillon, Preet K. (2020). Gender disparities in gastric cancer incidence patterns in India. Indian Journal of Cancer, 57(3), 293-299. https://doi.org/10.4103/ijc.IJC_432_19
  9. Keszei, András P., Goldbohm, R. Alexandra, Schouten, Leo J., Jakszyn, Paula, & van den Brandt, Piet A. (2019). Dietary N-nitroso compounds and risk of gastric cancer: Results from the Netherlands Cohort Study. International Journal of Cancer, 144(11), 2657-2670. https://doi.org/10.1002/ijc.31986
  10. Plummer, Martyn, Franceschi, Silvia, Vignat, Jérôme, Forman, David, & de Martel, Catherine. (2015). Global burden of gastric cancer attributable to Helicobacter pylori. International Journal of Cancer, 136(2), 487-490. https://doi.org/10.1002/ijc.28999
  11. Choi, Il Ju, Kook, Myeong-Cherl, Kim, Young-Il, Cho, Soo-Jeong, Lee, Jun Young, Kim, Chan Gyoo, Park, Boyoung, & Nam, Byung-Ho. (2020). Current status and future perspective of gastric cancer screening. Clinical Endoscopy, 53(3), 336-348. https://doi.org/10.5946/ce.2020.032
  12. Gyawali, Bishal, Shimokata, Tomoya, Honda, Kazunori, & Ando, Yuichi. (2021). Challenges in early cancer detection in low-income and middle-income countries. The Lancet Oncology, 22(8), e354-e365. https://doi.org/10.1016/S1470-2045(21)00058-6
  13. Jun, Jae Kwan, Choi, Kui Son, Lee, Hoo-Yeon, Suh, Mina, Park, Boyoung, Song, Su Hyun, Jung, Kyu-Won, & Lee, Chan Whan. (2017). Effectiveness of the Korean National Cancer Screening Program in reducing gastric cancer mortality. Cancer Research and Treatment, 49(3), 798-806. https://doi.org/10.4143/crt.2016.186

Ahead of Print Subscription Review Article
Volume 02
02
Received 04/05/2025
Accepted 22/05/2025
Published 27/12/2025
Publication Time 237 Days


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