Biodegradable Polymer Composite Materials for Long-Term Drug Release in Pharmacotherapy

Year : 2025 | Volume : 13 | Special Issue 04 | Page : 533 546
    By

    Chivate A.N.,

  • S.V. Patil,

  • Ashok Kr. Sharma,

  • Shivaji Jadhav,

  1. Assistant Professor, Department of Pharmacology, Krishna Vishwa Vidyapeeth (Deemed to be University), Krishna Institute of Pharmacy, Karad, Maharashtra, India
  2. Assistant Professor, Department of Mechanical Engineering, Vishwakarma Institute of Technology, Pune, Maharshtra, India
  3. Assistant Professor, Department of Pharmacy, Arya College of Pharmacy, Jaipur, Rajasthan, India
  4. Assistant Professor, Department of Mechanical Engineering, Dr. D.Y. Patil Institute of Technology, Pimpri, Pune, Maharshtra, India

Abstract

Biodegradable Polymer composite materials are a promising choice for controlled drug delivery because they let medicine be released slowly over time during treatment. These structures, which are made from safe, recyclable plastics, work well to make sure that drugs stay in the body for a long time. This means that patients will take their medicine less often and more consistently. As the body breaks down these structures, the drug inside slowly comes out at a steady rate. So, they are great for treating cancer and illnesses that last a long time. Polymers composite that break down naturally, such as PLGA, PCL, and PLA, are very bendable. They are utilised for a variety of medical disorders as they may be altered to deliver medications in different ways. These items assist the body repair over time by breaking down after a designated period. A drug’s release is influenced by the type of polymer employed, the weight of its molecules, and the way the matrix is constructed. These factors all affect the rate of release of the medication as well as the body’s absorption capacity. Using Polymer composite materials that can be recycled in medicine has several justifiable reasons. It can help therapy be more effective generally and reduce negative effects resulting from varying medication dosages. They might reduce the frequency of medication needed by individuals, therefore simplifying things for the patients. But issues like medications that break down either too slowly or too rapidly have to be resolved if we are to improve their usage in medicine.

Keywords: Biodegradable polymers composite, drug delivery, controlled release, pharmacotherapy, biocompatibility, chronic disease management.

[This article belongs to Special Issue under section in Journal of Polymer and Composites (jopc)]

How to cite this article:
Chivate A.N., S.V. Patil, Ashok Kr. Sharma, Shivaji Jadhav. Biodegradable Polymer Composite Materials for Long-Term Drug Release in Pharmacotherapy. Journal of Polymer and Composites. 2025; 13(04):533-546.
How to cite this URL:
Chivate A.N., S.V. Patil, Ashok Kr. Sharma, Shivaji Jadhav. Biodegradable Polymer Composite Materials for Long-Term Drug Release in Pharmacotherapy. Journal of Polymer and Composites. 2025; 13(04):533-546. Available from: https://journals.stmjournals.com/jopc/article=2025/view=220504


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Special Issue Subscription Original Research
Volume 13
Special Issue 04
Received 20/05/2025
Accepted 10/06/2025
Published 20/06/2025
Publication Time 31 Days
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