Development, Optimization and Evaluation of Polyherbal Gel Comprising of Azadirachta Indica, Calendula Officenalis, Turmeric and Aloe-vera for Treatment of Wound

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Year : 2025 | Volume : 02 | 02 | Page : –
    By

    Yogaraj Mahajan,

  • Vishal Gupta,

  1. Professor, Faculty of Pharmacy, Mansarovar Global University, Sehore, M.P. 466111, India
  2. Dean, Faculty of Pharmacy, Mansarovar Global University, Sehore, M.P. 466111, India

Abstract

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Azadirachta indica, Calendula officinalis, Turmeric (Curcuma longa), and Aloe-vera are known to possess numerous medicinal properties. These herbs have been traditionally used across various cultures for the treatment of a wide range of ailments due to their potent therapeutic effects. Individually, they have demonstrated efficacy in addressing conditions such as acne, diabetes, wound healing, gastric ulcers, first-degree burns, psoriasis, arthritis, and pneumonia. Additionally, they are known for their antimicrobial, anti-inflammatory, antifungal, antibacterial, and antimalarial properties, making them valuable components in traditional and modern herbal medicine. In the present study, a polyherbal gel formulation comprising Azadirachta indica, Calendula officinalis, Turmeric, and Aloe-vera was prepared with the objective of evaluating its wound-healing efficacy. Ten different formulations were developed and tested for drug release properties and drug content. Among these, formulations F-2, F-6, and F-9 demonstrated the highest percentage of drug release, showing approximately 95.98%, 91.3%, and 87.62% release respectively from the gel matrix. Furthermore, the drug content in these formulations was found to be notably high, with values of 96.86%, 97.82%, and 98.07% respectively. These findings indicate that the active constituents were well incorporated within the gel base. Further research on formulated gel shows its clinical effectiveness in the treatment of wound.

Keywords: Polyherbal gel, Azadirachta indica, Calendula officenalis, Turmeric, Aloe-vera, wound, Burn wound, hydroalcoholic, herbal formulation.

How to cite this article:
Yogaraj Mahajan, Vishal Gupta. Development, Optimization and Evaluation of Polyherbal Gel Comprising of Azadirachta Indica, Calendula Officenalis, Turmeric and Aloe-vera for Treatment of Wound. Recent Trends in Cosmetics. 2025; 02(02):-.
How to cite this URL:
Yogaraj Mahajan, Vishal Gupta. Development, Optimization and Evaluation of Polyherbal Gel Comprising of Azadirachta Indica, Calendula Officenalis, Turmeric and Aloe-vera for Treatment of Wound. Recent Trends in Cosmetics. 2025; 02(02):-. Available from: https://journals.stmjournals.com/rtc/article=2025/view=0


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Ahead of Print Subscription Original Research
Volume 02
02
Received 02/06/2025
Accepted 22/07/2025
Published 26/07/2025
Publication Time 54 Days
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