Percentage Changes According to Pathological Findings of Sentinel Lymph Node in Early and Early–like progressive Gastric Cancer

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This is an unedited manuscript accepted for publication and provided as an Article in Press for early access at the author’s request. The article will undergo copyediting, typesetting, and galley proof review before final publication. Please be aware that errors may be identified during production that could affect the content. All legal disclaimers of the journal apply.

Year : 2025 | Volume : 15 | Issue : 02 | Page :
    By

    Hyon Chol Jo,

  • Hak Song Jo,

  • Kum Hyok So,

  1. Researcher, Department of Pathology Pyongyang University of Medical Sciences, Pyongyang, Democratic People’s Republic of Korea
  2. Researcher, Department of Pathology, Pyongyang University of Medical Sciences, Pyongyang, Democratic People’s Republic of Korea
  3. Researcher, Department of Pathology, Pyongyang University of Medical Sciences, Pyongyang, Democratic People’s Republic of Korea

Abstract

Gastric cancer is considered to take the first place in incidence among visceral cancers in our country. We have studied to solve the problems to contribute gastric surgery practice, and the studying aim is to identify appearance of SLN, order of incidence and average amount. We selected 121 early and early-like progressive gastric cancer patients (Male: Female =2.7:1) who had undergone operations within last 10 years at Tumour Research Station of Medical Research Institute. we gradually injected 1ml of micro-activated charcoal saline liquid cantering the gastric cancer lesion throughout four cardinal directions into submucous and subserous tissue of the patients who had been diagnosed as early gastric cancer and confirmed to have the indication for an operation so that we could excise the coloured SLNs after 15-20 minutes with the lesion. we measured the size of the lesion pathomorphological, confirmed the macroscopic findings, took the tissue specimen, stained them with H-E under the general sampling principles and finally observed histopathological findings microscopically to confirm its histological findings, differentiation and microscopic depth. For the test of significance with the appearance of SLN according to pathological indications, we performed χ2-test and with the average amount of SLN, we performed t-test. The percentage changes of SLN presence according to pathological indications of early and early-like progressive cancer are like the following. The average number of sentinel lymph nodes (SLNs) identified was 1.41. Among these, the most frequently observed SLNs were the No. 5 lymph nodes (suprapyloric lymph nodes), accounting for 24.0%, followed by the No. 6 lymph nodes (subpyloric lymph nodes) at 18.2%, and the No. 1 lymph nodes (pyloric lymph nodes) at 11.6%.

Keywords: Sentinel Lymph Node, Early and Early–like progressive Gastric Cancer, Medical Research, histopathological, patients.

[This article belongs to Research and Reviews: A Journal of Medicine ]

How to cite this article:
Hyon Chol Jo, Hak Song Jo, Kum Hyok So. Percentage Changes According to Pathological Findings of Sentinel Lymph Node in Early and Early–like progressive Gastric Cancer. Research and Reviews: A Journal of Medicine. 2025; 15(02):-.
How to cite this URL:
Hyon Chol Jo, Hak Song Jo, Kum Hyok So. Percentage Changes According to Pathological Findings of Sentinel Lymph Node in Early and Early–like progressive Gastric Cancer. Research and Reviews: A Journal of Medicine. 2025; 15(02):-. Available from: https://journals.stmjournals.com/rrjom/article=2025/view=212385


References

  1. Lavy R, Kapiev A, Hershkovitz Y, et al. Tumor differentiation as related to sentinel lymph node status in gastric cancer. World J Gastrointest Surg. 2014 Jan 27;6(1):1–4.
  2. Can MF, Yagci G, Cetiner S. Sentinel lymph node biopsy for gastric cancer: Where do we stand? World J Gastrointest Surg. 2011 Sep 27;3(9):131–7.
  3. Yanagita S, Natsugoe S, Uenosono Y, et al. Detection of micrometastasis in sentinel node navigation surgery for gastric cancer. Surg Oncol. 2008;17(3):203–10.
  4. Symeonidis D, Tepetes K. Techniques and current role of sentinel lymph node (SLN) concept in gastric cancer surgery. Front Surg. 2019 Jan 5;5:1–9.
  5. Yahyapour N, Nedavalizadeh J, Azizi S, et al. Sentinel lymph node mapping and biopsy using radioactive tracer in gastric cancer. ANZ J Surg. 2014;84(7–8):454–8.
  6. An JY, Min JS, Hur H, et al. Laparoscopic sentinel node navigation surgery versus laparoscopic gastrectomy with lymph node dissection for early gastric cancer: Short-term outcomes of a multicenter randomized controlled trial (SENORITA). Br J Surg. 2020 Aug;107(10):1429–39.
  7. Natsugoe S, Arigami T, Uenosono Y, et al. Novel surgical approach based on the sentinel node concept in patients with early gastric cancer. Ann Gastroenterol Surg. 2017 Aug;1(2):180–5.
  8. Takahashi N, Nimura H, Fujita T, et al. Quantitative assessment of visual estimation of the infrared indocyanine green imaging of lymph nodes retrieved at sentinel node navigation surgery for gastric cancer. BMC Surg. 2016 Apr 27;16(1):35.
  9. Ichikura T, Chochi K, Sugasawa H, et al. Individualized surgery for early gastric cancer guided by sentinel node biopsy. Surgery. 2006 Apr;139(4):501–7.
  10. Niihara M, Takeuchi H, Nakahara T, et al. Sentinel lymph node mapping for 385 gastric cancer patients. J Surg Res. 2016 Jul;200(1):73–81.
  11. Takeuchi H, Goto O, Yahagi N, et al. Function-preserving gastrectomy based on the sentinel node concept in early gastric cancer. Gastric Cancer. 2017 Jan;20(Suppl 1):53–9.
  12. Shimada A, Takeuchi H, Ono T, et al. Pylorus-preserving surgery based on the sentinel node concept in early gastric cancer. Ann Surg Oncol. 2016 Dec;23(Suppl 5):4247–52.
  13. Kitayama J, Ishigami H, Ishikawa M, et al. Hyaluronic acid is a useful tool for intraoperative sentinel node detection in gastric cancer surgery. Surgery. 2007 Jun;141(6):815–20.
Regular Issue Subscription Original Research
Volume 15
Issue 02
Received 30/01/2025
Accepted 28/02/2025
Published 05/06/2025
Publication Time 126 Days
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