Nanorobots: The Fight against Cholesterol

Year : 2025 | Volume : 27 | Issue : 02 | Page : 23 32
    By

    Kazi Kutubuddin Sayyad Liyakat,,

  1. Professor & Head, Department of Electronics and Telecommunication Engineering, Brahmdevdada Mane Institute of Technology, Maharashtra, India

Abstract

Cardiovascular disease (CVD) rests leading reason of death globally, with atherosclerosis, the buildup of plaque in arteries, playing a central role. Current treatment strategies, including lifestyle changes and medications, often fall short in completely reversing or preventing the progression of atherosclerosis. This has spurred the exploration of innovative approaches, with nanorobotics emerging as a promising avenue for targeted plaque control and high-density lipoprotein (HDL) enhancement. This article discusses how nanorobots could transform the way we manage cholesterol and fight atherosclerosis. We will delve into the mechanisms by which these microscopic machines could be employed to specifically target and remove atherosclerotic plaques, while simultaneously promoting the production and function of HDL, the “good cholesterol.” Traditional therapies often have systemic effects, impacting various parts of the body even when the primary target is the atherosclerotic plaque. Nanorobots, however, offer the potential for highly targeted delivery and action. Imagine swarms of these miniature machines navigating through the bloodstream, guided by sophisticated sensors and algorithms. HDL helps clear excess cholesterol from the body’s tissues and carries it to the liver, where it is eliminated. Enhancing HDL levels and improving its functionality are key therapeutic goals in cholesterol management. While nanorobotics in cardiology is still in its infancy, preclinical studies have yielded encouraging results. For instance, some studies have demonstrated the ability of nanorobots to selectively target and remove plaque in animal models. Other research has shown the potential of nanorobots to deliver drugs directly to atherosclerotic lesions, improving treatment outcomes. These in vitro and in vivo studies are paving the way for human trials.

Keywords: Nanorobots, Cholesterol, Plaque, HDL, Targeted drug delivery

[This article belongs to Nano Trends – A Journal of Nano Technology & Its Applications ]

How to cite this article:
Kazi Kutubuddin Sayyad Liyakat,. Nanorobots: The Fight against Cholesterol. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(02):23-32.
How to cite this URL:
Kazi Kutubuddin Sayyad Liyakat,. Nanorobots: The Fight against Cholesterol. Nano Trends – A Journal of Nano Technology & Its Applications. 2025; 27(02):23-32. Available from: https://journals.stmjournals.com/nts/article=2025/view=205244


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Regular Issue Subscription Review Article
Volume 27
Issue 02
Received 21/02/2025
Accepted 21/03/2025
Published 29/03/2025
Publication Time 36 Days
1,138

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