Innovation in Phytomedicine: From Ancient Remedies to Modern Therapies

Year : 2025 | Volume : 14 | Issue : 01 | Page : 24 33
    By

    Mohd Wasiullah,

  • Piyush Yadav,

  • Girijesh Yadav,

  • Rahul Kumar,

  1. Principal, Department of Pharmacy, Prasad Institute of Technology Jaunpur, Uttar Pradesh, India
  2. Academic Head, Department of Pharmacy, Prasad Institute of Technology Jaunpur, Uttar Pradesh, India
  3. Associate Professor, Department of Pharmacy, Prasad Institute of Technology Jaunpur, Uttar Pradesh, India
  4. Scholar, Department of Pharmacy, Prasad Institute of Technology Jaunpur, Uttar Pradesh, India

Abstract

Phytomedicine, the use of plant-derived substances for therapeutic purposes, has evolved from a ncient herbal remedies to modern clinical applications, significantly influencing healthcare practices worldwide. This review explores the historical context of phytomedicine, highlighting its roots in ancient civilizations such as Egypt, China, and India, where plants were recognized for their healing properties. We discuss key innovations in the field, including advancements in pharmacognosy, clinical research, and biotechnology, which have led to the validation and standardization of herbal medicines. Additionally, we address the challenges faced by phytomedicine, such as variability in plant quality, regulatory hurdles, and public perception issues. The future of phytomedicine lies in the integration of traditional knowledge with modern scientific approaches, promoting personalized therapies and sustainable practices. Ultimately, this article underscores the potential of phytomedicine to provide innovative and effective health solutions while enhancing global health outcomes.

Keywords: Phytomedicine, Herbal medicine, Plant-based therapies, Traditional medicine, Ancient remedies, Active plant compounds, Natural medicine

[This article belongs to Research & Reviews : Journal of Herbal Science ]

How to cite this article:
Mohd Wasiullah, Piyush Yadav, Girijesh Yadav, Rahul Kumar. Innovation in Phytomedicine: From Ancient Remedies to Modern Therapies. Research & Reviews : Journal of Herbal Science. 2025; 14(01):24-33.
How to cite this URL:
Mohd Wasiullah, Piyush Yadav, Girijesh Yadav, Rahul Kumar. Innovation in Phytomedicine: From Ancient Remedies to Modern Therapies. Research & Reviews : Journal of Herbal Science. 2025; 14(01):24-33. Available from: https://journals.stmjournals.com/rrjohs/article=2025/view=192112


References

  1. Yin J, Wei L, Wang N, Li X, Miao M. Efficacy and safety of adjuvant curcumin therapy in ulcerative colitis: A systematic review and meta-analysis. J Ethnopharmacol. 202210;289:115041. doi: 10.1016/j.jep.2022.115041.
  2. Canistro D, Chiavaroli A, Cicia D, Cimino F, Curro D, Dell’Agli M, et al. The pharmacological basis of the curcumin nutraceutical uses: An update. Pharmadvances. 2021;3(2):421–466. doi: 10.36118/pharmadvances.2021.06.
  3. Hewlings SJ, Kalman DS. Curcumin: A review of its effects on human health. Foods. 2017;6(10):92. doi: 10.3390/foods6100092.
  4. Yin J, Wei L, Wang N, Li X, Miao M. Efficacy and safety of adjuvant curcumin therapy in ulcerative colitis: A systematic review and meta-analysis. J Ethnopharmacol. 2022;289:115041.
  5. Mohite P, Puri A, Bharati D, Singh S. Polyphenol‐ encapsulated nanoparticles for the treatment of chronic metabolic diseases. In: Role of flavonoids in chronic metabolic diseases: From bench to clinic. Wiley; 2024. pp. 375–416.
  6. Canistro D, Chiavaroli A, Cicia D, Cimino F, Curro D, Dell’Agli M, et al. The pharmacological basis of the curcumin nutraceutical uses: An update. Pharmadvances. 2021;3(2):421-66.
  7. Sharma H, Anand A, Halagali P, Inamdar A, Pathak R, Taghizadeh‐Hesary F, et al. Advancement of nanoengineered flavonoids for chronic metabolic diseases. In: Role of Flavonoids in Chronic Metabolic Diseases: From Bench to Clinic. Wiley; 2024. pp. 459–510.
  8. Marsman D, Belsky DW, Gregori D, Johnson MA, Low Dog T, Meydani S, et al. Healthy ageing: The natural consequences of good nutrition—A conference report. Eur J Nutr. 2018;57(Suppl 2):15–34. doi: 10.1007/s00394-018-1723-0.
  9. Kiefte-de Jong JC, Mathers JC, Franco OH. Nutrition and healthy ageing: The key ingredients. Proc Nutr Soc. 2014;73(2):249–259. doi: 10.1017/S0029665113003881.
  10. Fekete M, Szarvas Z, Fazekas-Pongor V, Feher A, Csipo T, Forrai J, et al. Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases. Nutrients. 2022;15(1):47. doi: 10.3390/nu15010047.
  11. Rosso AM. Methods and management in ancient Egyptian and Greek medicine. Hist Philos Med. 2023;5(3):14. doi: 10.53388/HPM2023014.
  12. Reyes-García V. The relevance of traditional knowledge systems for ethnopharmacological research: Theoretical and methodological contributions. J Ethnobiol Ethnomed. 2010;6:1–2. doi: 10.1186/1746-4269-6-32.
  13. Kizhakkeveettil A, Parla J, Patwardhan K, Sharma A, Sharma S. History, Present and Prospect of Ayurveda. In: History, Present and Prospect of World Traditional Medicine. 2024. pp. 1–72.
  14. Bagde AB, Ramteke AT, Sawant RS, Bhingare SD, Nikumbh MB. Sushruta Samhia-A unique encyclopedia of ayurvedic surgery. World J Pharm Pharm Sci. 2017;6(4):750–767. doi: 10.20959/wjpps20174-8948.
  15. Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007;70(3):461–477. doi: 10.1021/np068054v.
  16. Najmi A, Javed SA, Al Bratty M, Alhazmi HA. Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents. Molecules. 2022;27(2):349. doi: 10.3390/molecules27020349.
  17. Patwardhan B. Ethnopharmacology and drug discovery. J Ethnopharmacol. 2005;100(1-2):50–52. doi: 10.1016/j.jep.2005.06.006.
  18. Orhan H, Arzuk E, Karaku F, Ergüç A. Toxicology of Herbal Medicines. In: Toxicology for the Health and Pharmaceutical Sciences. CRC Press; 2021. pp. 189–220.
  19. A comprehensive reference book on the use of herbal medicines, their properties, and their application in clinical practice.
  20. Balandrin MF, Klocke JA, Wurtele ES, Bollinger WH. Natural plant chemicals: Sources of industrial and medicinal materials. Science. 1985;228(4704):1154–1160. doi: 10.1126/science.3890182.
  21. Karunamoorthi K, Jegajeevanram K, Vijayalakshmi J, Mengistie E. Traditional medicinal plants: A source of phytotherapeutic modality in resource-constrained health care settings. J Evid Based Complementary Altern Med. 2013;18(1):67–74. doi: 10.1177/2156587212460241
  22. Snyder M, Lindquist R, Tracy MF, Chen KM. Evolution and Use of Complementary Therapies and Integrative Health Approaches. In: Complementary Therapies in Nursing: Promoting Integrative Care. Springer Publishing Company; 2022. pp. 3–20.
  23. Peschel W, Alvarez BM. Harmonised European standards as a basis for the safe use of herbal medicinal products and their marketing authorisation in European Union member states. Pharmaceutical Medicine. 2018;32:275–293. doi: 10.1007/s40290-018-0242-x.
  24. Briskin DP. Medicinal plants and phytomedicines. Linking plant biochemistry and physiology to human health. Plant Physiol. 2000;124(2):507–514. doi: 10.1104/pp.124.2.507.
  25. Tiwari R, Latheef SK, Ahmed I, Iqbal HM, Bule MH, Dhama K, et al. Herbal immunomodulators-a remedial panacea for designing and developing effective drugs and medicines: Current scenario and future prospects. Curr Drug Metab. 2018;19(3):264–301. doi: 10.2174/1389200219666180129125436
Regular Issue Subscription Review Article
Volume 14
Issue 01
Received 14/12/2024
Accepted 31/12/2024
Published 03/01/2025
Publication Time 20 Days
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