Supyar Singh,
Vishal Gupta,
- Faculty of Pharmacy, Mansarovar Global University, Madhya Pradesh, India
- Dean, Faculty of Pharmacy, Mansarovar Global University, Madhya Pradesh, India
Abstract
A systematic study was conducted on extracts of Cordia myxa and Canscora diffusa to evaluate their qualitative chemical composition, phytochemical content, and antidiabetic activity. Then the Poly herbal extract is prepared with the selected plant powders, subjected to acute-toxicity studies for dose fixation. The herbal extracts formulation was prepared taking three selected dosages. The preparations are evaluated for anti-diabetic activity using Steptozotocine and Alloxan induced diabetic models in rats. The polyherbal formulation was found to include flavonoids, phenolic compounds, glycosides, sterols, phenolic steroids, and carbohydrates. Toxicity tests, conducted following OECD guidelines, showed no harmful effects at a dose of 2000 mg/kg. Additionally, the formulation demonstrated a dose-dependent antidiabetic effect in a model of Alloxan-induced hyperglycemia.
Keywords: Cordia myxa, Canscora diffusa, hyperglycemia, diabetes, polyherbal formulation
[This article belongs to Research & Reviews: A Journal of Pharmacology ]
Supyar Singh, Vishal Gupta. Biochemical Estimation of Allaxon Induced Hyperglycemia in Rats Treated with Polyherbal Preparation of Two of Indian Medicinal Plants Cordia Myxa and Canscora Diffusa. Research & Reviews: A Journal of Pharmacology. 2024; 14(03):52-60.
Supyar Singh, Vishal Gupta. Biochemical Estimation of Allaxon Induced Hyperglycemia in Rats Treated with Polyherbal Preparation of Two of Indian Medicinal Plants Cordia Myxa and Canscora Diffusa. Research & Reviews: A Journal of Pharmacology. 2024; 14(03):52-60. Available from: https://journals.stmjournals.com/rrjop/article=2024/view=186760
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Research and Reviews: A Journal of Pharmacology
| Volume | 14 |
| Issue | 03 |
| Received | 24/10/2024 |
| Accepted | 27/11/2024 |
| Published | 02/12/2024 |
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