Ranjitha Rajan,
S.N. Kumar,
- Research Scholar, Lincoln University College-Kota Bharu, Malaysia, Assistant Professor, Department of Electronics and Communication Engineering, Amal Jyothi College of Engineering, Koovappally, Kerala, India
- Associate Professor, Department of Electrical and Electronics Engineering, Amal Jyothi College of Engineering, Koovappally, Kerala, India
Abstract
Optical coherence tomography (OCT) is a non-invasive technique that generates high-resolution, detailed cross-sectional images of biological tissues. By utilizing low-coherence interferometry, OCT enables visualization of tissue microstructure with micron-scale resolution, making it useful in various medical fields such as ophthalmology, cardiology, and dermatology. In ophthalmology, OCT is extensively used for diagnosing and monitoring retinal diseases like macular degeneration and diabetic retinopathy, allowing doctors to assess changes in tissue morphology over time. Moreover, OCT plays a crucial role in guiding surgical procedures, assessing treatment efficacy, and advancing our understanding of disease pathogenesis. Its ability to provide detailed, real-time images with minimal patient discomfort has made OCT a cornerstone technology in modern medical imaging, revolutionizing patient care and research practices. This survey comprehensively reviews the recent advances in preprocessing, segmentation, and deep learning-based classification of retinal OCT images, highlighting the latest techniques, challenges, and future directions for improving diagnostic accuracy and clinical applications.
Keywords: Optical coherence tomography (OCT), age-related macular degeneration (AMD), diabetic retinopathy (DR), convolutional neural networks (CNNs)
[This article belongs to Journal of Image Processing & Pattern Recognition Progress ]
Ranjitha Rajan, S.N. Kumar. Survey on Retinal OCT Image Preprocessing, Segmentation, and Deep Learning Based Classification. Journal of Image Processing & Pattern Recognition Progress. 2024; 11(03):1-9.
Ranjitha Rajan, S.N. Kumar. Survey on Retinal OCT Image Preprocessing, Segmentation, and Deep Learning Based Classification. Journal of Image Processing & Pattern Recognition Progress. 2024; 11(03):1-9. Available from: https://journals.stmjournals.com/joipprp/article=2024/view=177857
References
- Abràmoff MD, Garvin MK, Sonka M. Retinal imaging and image analysis. IEEE Rev Biomed Eng. 2010;3:169–208. DOI: 10.1109/RBME.2010.2084567. PubMed: 22275207.
- Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, et al. Optical coherence tomography. Science. 1991;254:1178–81. DOI: 10.1126/science.1957169.
- Chhablani PP, Ambiya V, Nair AG, Bondalapati S, Chhablani J. Retinal findings on OCT in systemic conditions. Ophthalmology. Taylor & Francis. 2018;33:525–46. DOI: 10.1080/08820538.1332233. PubMed: 28640657.
- Jaffe GJ, Caprioli J. Optical coherence tomography to detect and manage retinal disease and glaucoma. Am J Ophthalmol. 2004;137:156–69. DOI: 10.1016/s0002-9394(03)00792-x. PubMed: 14700659.
- Gabriele ML, Wollstein G, Ishikawa H, Xu J, Kim J, Kagemann L, et al. Three-dimensional optical coherence tomography imaging: Advantages and advances. Prog Retin Eye Res. 2010;29:556–79. DOI: 10.1016/j.preteyeres.2010.05.005. PubMed: 20542136.
- Chauhan DS, Marshall J. The interpretation of optical coherence tomography images of the retina. Invest Ophthalmol Vis Sci. 1999;40:2332–42. PubMed: 10476800.
- Salvatelli A, Bizai G, Barbosa G, Drozdowicz B, Delrieux C. A comparative analysis of pre-processing techniques in colour retinal images. J Phys Conf Ser. 2007;90:012069. DOI: 10.1088/1742-6596/90/1/012069.
- Setiawan AW, Mengko TR, Santoso OS, Suksmono AB. Color retinal image enhancement using CLAHE. International Conference on ICT for Smart Society, Jakarta, Indonesia. 2013, pp. 1–3. DOI: 10.1109/ICTSS.2013.6588092.
- Goatman KA, Whitwam AD, Manivannan A, Olson JA, Sharp PF. Colour normalisation of retinal images. In: Proceedings of Medical Image Understanding and Analysis. University of Sheffield: UK; 2003. p. 49–52.
- Marrugo AG, Millán MS. Retinal image analysis: Preprocessing and feature extraction. J Phys Conf Ser. 2011;274:012039. DOI: 10.1088/1742-6596/274/1/012039.
- Soomro TA, Ali A, Jandan NA, Afifi AJ, Irfan M, Alqhtani S, et al. Impact of novel image preprocessing techniques on retinal vessel segmentation. Electronics. 2021;10:2297. DOI: 10.3390/
- Hernandez-Matas C, Argyros AA, Zabulis X. Retinal image preprocessing, enhancement, and registration. Comput Retin Image Anal. 2019;59–77.
- Chakka L. Analyzing optimal image preprocessing techniques for automated retinal disease diagnosis. Nat High Sch J Sci. 2023;1–8.
- Bahr T, Vu TA, Tuttle JJ, Iezzi R. Deep learning and machine learning algorithms for retinal image analysis in neurodegenerative disease: Systematic review of datasets and models. Transl Vis Sci Technol. 2024;13:16. DOI: 10.1167/tvst.13.2.16. PubMed: 38381447.
- Panda NR, Sahoo AK. A detailed systematic review on retinal image segmentation methods. J Digit Imaging. 2022;35:1250–70. DOI: 10.1007/s10278-022-00640-9. PubMed: 35508746.
- Shatil SR, Kabir MM. Retinal OCT image classification based on CNN and transfer learning. In: International Conference on Soft Computing and Pattern Recognition. Springer Nature Switzerland: Cham; 2022. p. 433–44.
- DeBuc DC. A review of algorithms for segmentation of retinal image data using optical coherence tomography. Image Segmentation. 2011;1:15–54.
- Pekala M, Joshi N, Liu TYA, Bressler NM, DeBuc DC, Burlina P. Deep learning based retinal OCT segmentation. Comput Biol Med. 2019;114:103445. DOI: 10.1016/j.compbiomed.2019.103445. PubMed: 31561100.
- Ramesh KKD, Kumar GK, Swapna K, Datta D, Rajest SS. A review of medical image segmentation algorithms. EAI Endorsed Trans Pervasive Health Technol. 2021;7:e6. DOI: 10.4108/eai.12-4-2021.169184.
- Alqudah AM, AlTantawi M, Alqudah A. Artificial intelligence hybrid system for enhancing retinal diseases classification using automated deep features extracted from OCT images. Int J Intell Syst Appl Eng. 2021;9:91–100. DOI: 10.18201/ijisae.2021.236.
- Saha Tchinda BS, Tchiotsop D, Noubom M, Louis-Dorr V, Wolf D. Retinal blood vessels segmentation using classical edge detection filters and the neural network. Informatics Med Unlocked. 2021;23:100521. DOI: 10.1016/j.imu.2021.100521.
- Luo S, Yang J, Gao Q, Zhou S, Zhan CA. The edge detectors suitable for retinal OCT image segmentation. J Healthc Eng. 2017;2017:3978410. DOI: 10.1155/2017/3978410. PubMed: 2906
- Kugelman J, Alonso-Caneiro D, Read SA, Vincent SJ, Collins MJ. Enhanced OCT chorio-retinal segmentation in low-data settings with semi-supervised GAN augmentation using cross-localisation. Comput Vis Image Underst. 2023;237:103852. DOI: 10.1016/j.cviu.2023.103852.
- Orujov F, Maskeliūnas R, Damaševičius R, Wei WJ. Fuzzy based image edge detection algorithm for blood vessel detection in retinal images. Appl Soft Comput. 2020;94:106452. DOI: 10.1016/j.asoc.2020.106452.
- Xiaoming L, Ke X, Peng Z, Jiannan C. Edge detection of retinal OCT image based on complex shearlet transform. IET Image Process. 2019;13:1686–93. DOI: 10.1049/iet-ipr.2018.6634.
- González-López A, Remeseiro B, Ortega M, Penedo MG, Charlón P. A texture-based method for choroid segmentation in retinal EDI-OCT images. Comput Aided Syst Theory EUROCAST. Springer Int Publ. 2015;15:487–93.
- Iqbal E, Niaz A, Memon AA, Asim U, Choi KN. Saliency-driven active contour model for image segmentation. IEEE Access. 2020;8:208978–91. DOI: 10.1109/ACCESS.2020.3038945.
- Thompson AC, Jammal AA, Berchuck SI, Mariottoni EB, Medeiros FA. Assessment of a segmentation-free deep learning algorithm for diagnosing glaucoma from optical coherence tomography scans. JAMA Ophthalmol. 2020;138:333–9. DOI: 10.1001/jamaophthalmol.2019.
PubMed: 32053142. - Du G, Cao X, Liang J, Chen X, Zhan Y. Medical image segmentation based on U-Net: A review. J Imaging Sci Technol. 2020;64:020508–501. DOI: 10.2352/J.ImagingSci.Technol.2020.64.2.
- Tong Y, Lu W, Yu Y, Shen Y. Application of machine learning in ophthalmic imaging modalities. Eye Vis (Lond). 2020;7:22. DOI: 10.1186/s40662-020-00183-6. PubMed: 32322599.
- Badar M, Haris M, Fatima A. Application of deep learning for retinal image analysis: A review. Comput Sci Rev. 2020;35:100203. DOI: 10.1016/j.cosrev.2019.100203.
- Shyla NSJ, Emmanuel WRS. Glaucoma detection using multiple feature set with recurrent neural network. Comput J. 2023;66:2426–36. DOI: 10.1093/comjnl/bxac093.
- Alsaih K, Lemaitre G, Rastgoo M, Massich J, Sidibé D, Meriaudeau F. Machine learning techniques for diabetic macular edema (DME) classification on SD-OCT images. Biomed Eng Online. 2017;16:68. DOI: 10.1186/s12938-017-0352-9. PubMed: 28592309.
- Akinniyi O, Rahman MM, Sandhu HS, El-Baz A, Khalifa F. Multi-stage classification of retinal OCT using multi-scale ensemble deep architecture. Bioengineering. 2023;10:823. DOI: 10.3390/bioengineering10070823. PubMed: 37508850.s
- Papandrianos NI, Feleki A, Papageorgiou EI, Martini C. Deep learning-based automated diagnosis for coronary artery disease using SPECT-MPI images. J Clin Med. 2022;11:3918. DOI: 10.3390/jcm11133918. PubMed: 35807203.
- SenGupta S, Singh A, Leopold HA, Gulati T, Lakshminarayanan V. Ophthalmic diagnosis using deep learning with fundus images: A critical review. Artif Intell Med. 2020;102:101758. DOI: 10.1016/j.artmed.2019.101758. PubMed: 31980096.
- Panchal S, Naik A, Kokare M, Pachade S, Naigaonkar R, Phadnis P, et al. Retinal fundus Multi-Disease Image Dataset (RFMiD) 2.0: A dataset of frequently and rarely identified diseases. Data. 2023;8:29. DOI: 10.3390/data8020029.

Journal of Image Processing & Pattern Recognition Progress
| Volume | 11 |
| Issue | 03 |
| Received | 20/06/2024 |
| Accepted | 25/09/2024 |
| Published | 11/10/2024 |
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