Mehak Jain,
Kaushiki Patel,
- Research Scholar,, Department of Pharmaceutics, Indore Professional Studies Academy, College of Pharmacy, Rajendra Nagar, Bijalpur, Indore,, Madhya Pradesh,, India
- Research Scholar,, Department of Pharmaceutics, Indore Professional Studies Academy, College of Pharmacy, Rajendra Nagar, Bijalpur, Indore,, Madhya Pradesh,, India
Abstract
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Pharmaceutical industries frequently use simulation software with real-time responses for a variety of purposes, such as dissolution simulation. In essence, it is a tool that let the user to simulate an operation and see it happen without actually conducting it. Equipments are frequently designed using simulation software to ensure that the finished output will be as near as to the design specifications as possible without costly process adjustments. Advanced computer programs can simulate power system behavior, complex biological process. These are employed to simulate physical responses in real time. A set of mathematical formulas are used to simulate real-world phenomena in simulation software. Simulator software is frequently used in equipment design to get the finished product as near to the design parameters as feasible without having to make expensive process adjustments. The purpose of simulation software is to examine the feasibility and reproducibility of developing an in vitro/in vivo interaction using GastroPLUSTM, PK- Sim®, Simcyp®, and DDDPlus (IVIVR). These findings emphasize the significance of choosing a suitable experimental strategy to determine the in vitro dissolution rate, which will later be used as a basis to create in vitro- in vivo correlations.
Keywords: Dissolution Simulation software, vitro-in vivo relationship (IVIVR), GastroPLUS™, PK-Sim®, Simcyp®, DDDPlus.
Mehak Jain, Kaushiki Patel. A Brief Review on Dissolution Simulation Software. Research & Reviews: A Journal of Pharmaceutical Science. 2024; ():-.
Mehak Jain, Kaushiki Patel. A Brief Review on Dissolution Simulation Software. Research & Reviews: A Journal of Pharmaceutical Science. 2024; ():-. Available from: https://journals.stmjournals.com/rrjops/article=2024/view=170709
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| Volume | |
| Received | July 23, 2024 |
| Accepted | August 27, 2024 |
| Published | September 7, 2024 |