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Open Access
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Kanav Gupta, Ravi Kumar Chittoria, Padmalakshmi Bharathi Mohan, Jacob Antony Chakia,
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Abstract
nScarring is commonly caused by an imbalance between collagen synthesis and degradation. One promising approach to mitigate scar formation involves the use of onion extract, known for its ability to inhibit fibroblast activity, which plays a key role in the development of scars. Despite the widespread use of onion extract in various commercial scar treatment products, the exact molecular mechanisms through which it exerts its scar-reducing effects remain unclear.This study is designed to evaluate the effectiveness of an onion extract gel in enhancing scar appearance and reducing scar formation. The primary objective is to assess whether the application of onion extract gel can significantly improve the visual and structural characteristics of scars. By understanding the extent to which onion extract gel influences scar healing, the study aims to provide more concrete evidence supporting its use in dermatological treatments.Participants in the study will apply the onion extract gel to their scars over a predetermined period. Various parameters, such as scar size, color, texture, and overall appearance, will be systematically measured and compared before and after treatment. Additionally, any side effects or adverse reactions will be closely monitored to ensure the safety and tolerability of the gel.Through this comprehensive evaluation, the study seeks to elucidate the potential benefits of onion extract gel in scar management. The findings could lead to a better understanding of how onion extract interacts with skin tissues at the molecular level, potentially revealing new insights into its mechanisms of action. Ultimately, this research aims to contribute to the development of more effective and scientifically validated treatments for scarring, offering improved outcomes for individuals seeking to enhance their skin’s appearance and health.By shedding light on the effectiveness of onion extract gel, this study may pave the way for its broader adoption in clinical practice and inspire further research into natural remedies for scar reduction.
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Keywords: Scar reduction, onion extract gel, donor site, cost-effective,shedding light
n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews : Journal of Surgery(rrjos)]
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References
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.Chanprapaph, K., Tanrattanakorn, S., Wattanakrai, P., Wongkitisophon, P., & Vachiramon, V. (2012). Effectiveness of Onion Extract Gel on Surgical Scars in Asians. Dermatology Research and Practice, 2012.
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| Volume | 13 | |
| [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] | 02 | |
| Received | May 16, 2024 | |
| Accepted | May 20, 2024 | |
| Published | June 5, 2024 |
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