International Journal of Genetic Engineering and Recombination Cover

International Journal of Genetic Engineering and Recombination

Editors Overview

ijger maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

CRISPER-Cas 9 in Eliminating Targeted Bacterial Population

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

Genetic engineering is of great interest due to the wide range of potential applications in a wide range of scientific fields. This set of technologies allows for novel practices such as the development of drought-resistant plant species, the modification of human pluripotent stem cells, and even the creation of genetically modified monkeys. Bacteriophages are viruses that infect bacteria and replicate using their genetic machinery. Bacteria developed an ingenious adaptive defense system, clustered regularly interspaced short palindromic repeats, to protect themselves from this type of invader (CRISPR). Researchers quickly realized that a specific type of CRISPR system, CRISPR-Cas9, could be modified into a simple and efficient genetic engineering technology with several advantages over existing systems. This discovery triggered a genetics revolution, with new and improved CRISPR systems being used in numerous in vitro and in vivo experiments in recent years. This review explains how CRISPR-Cas systems work as a means of bacterial immunity against phage invasion and how these systems were designed to generate new genetic manipulation tools. New CRISPR-Cas technologies and their potential applications in healthcare and other fields of science are also discussed. This technique, however, had limitations. There was a risk of mismatch and interference of the exogenous gene with endogenous sequences that were not meant to be altered because it relied on the random insertion of a DNA fragment.

Keywords

CRISPR, Cas9, Genetic engineering, Gene editing, Bacteria

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

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Journal Name

International Journal of Genetic Engineering and Recombination

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