International Journal of Computational Biology and Bioinformatics Cover

International Journal of Computational Biology and Bioinformatics

Editors Overview

ijcbb maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

Application of Electron microscopy for virus detection

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

Electron Microscopy (EM) is a strong diagnostic device used to aid the determination of Kidney Sickness, Muscle Problems, Neurological Issues, Ciliary Brokenness, Viral Gastroenteritis, Viral Contaminations, or any issue that might profit from the investigation of the fine structures of a biopsy. The high-resolution capacity of the electron microscope instrument is because of the small wavelength of the electron, roughly 0.004 nm for a 100-keV electron, contrasted and roughly 500 nm for visual light. The goal of the cutting-edge electron microscope lens is 0.2 nm; interestingly, that of a decent light microscope is 200 nm. Electron microscopy (EM) is a fundamental apparatus in the identification and examination of virus replication. New EM strategies and continuous specialized upgrades offer an expansive range of uses, permitting inside and out examination of viral effects on the host as well as the climate. For sure, utilizing the most state-of-the-art electron cryomicroscopy techniques, such examinations are presently near the nuclear goal. In blend with bioinformatics, the progress from 2D imaging to 3D rebuilding permits underlying and practical examinations that expand and increase our insight into the shocking variety in infection design and way of life. In blend with confocal laser checking microscopy, EM empowers live imaging of cells and tissues with the high-goal examination. Here, we depict the urgent pretended by EM in the investigation of infections, from primary examination to the organic importance of the viral metagenome (virome). Different tests including molecular and serological strategies expect that a particular test is accessible for infection recognizable proof. EM doesn’t need a live or intact virus; it has been utilized to distinguish variola infection in tainted tissue saved for a long time, by and large, in unknown solutions. Exotic infections in creatures have likewise been distinguished by EM. For instance, a ranavirus was identified in green pythons in the primary exhibit of systemic viral disease in snakes, and confirmation of a herpesvirus in kangaroos, at first recognized with an agreement herpesvirus PCR, was made by EM assessment of the separate filled-in tissue culture.

Keywords

Electron microscopy, Diagnosis, Virus detection, Virus replication, High-resolution

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

Participating journals: