Editors Overview

tdd maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

Lysosome-based drug-delivery

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

Lysosomes are membrane-enclosed organelles that contain an array of enzymes capable of breaking down all types of biological polymers—proteins, nucleic acids, carbohydrates, and lipids. The outflow of the byproducts of intralysosomal catabolism is facilitated by their physiological function. With rare exceptions, these porters are uncommon candidates for the translocation of xenobiotics across the lysosome membrane due to their specialization. Passive diffusion is most likely to be used to achieve efflux from the lysosome where it is possible. Experimental investigations of passive diffusion over the lysosome membrane have revealed that it shares many properties with other biological membranes. When drug delivery options are considered that involve a drug-conjugate reaching the lysosome compartment and drug release there by the lysosomal enzymes, predictions of how easily molecules will pass through lysosomal membranes are valuable. These methods won’t work if the medication can’t exit the lysosome and get to the cells where it needs to act pharmacologically.

Keywords

Lysosome therapeutics, Drug delivery, Bioavailability, Lysosome manufacturing, Molecular engineering

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

Participating journals:


2394-7268

Journal Name

Trends in Drug Delivery

Abbrivation


tdd

ISSN


2394-7268

Since

2014

APC

950  $