Editors Overview

tdd maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

Pharmacological targets that are suitable for treating Genomic disorders

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

The determination of pharmacological targets is a crucial phase in the drug design process in the biomedical field. Therefore, it is tempting to also use this model to describe genetic diseases. Although the model works well for genetic disorders with gain-of-function, it is less effective for the majority of genetic diseases with loss of function. The majority of common diseases, along with hereditary diseases with gain-of-function, are defined by the activation of particular pathways or the ectopic activity of proteins, which make excellent targets. On the other hand, loss-of-function genetic illnesses are brought on by the deficiency of a single protein and may have widespread effects. It may be challenging to identify pharmaceutically relevant targets for such disorders since the concept of a pharmacological target is less exact. To prevent allocating resources to ineffective techniques in the search for cures, it is important to take into account this important but usually overlooked element of loss-of-function genetic illnesses.

Keywords

Genetic diseases, Target-based drug design, Malfunction, Enzyme encoding genes, Phenotype

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

Participating journals:


2394-7268

Journal Name

Trends in Drug Delivery

Abbrivation


tdd

ISSN


2394-7268

Since

2014

APC

950  $