International Journal of Polymer Science & Engineering Cover

International Journal of Polymer Science & Engineering

ISSN: 2455-8745

Editors Overview

ijpse maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

Liposome-based methods are used to create polymersomes

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

Hollow shell nanoparticles (NPs) called polymersomes can be used to distribute medications. It has been demonstrated that biodegradable polymersomes may load, distribute, and absorb drug combinations in the cytosol by taking advantage of the block copolymer vesicles’ thick membrane, aqueous lumen, and pH-triggered release within endolysosomes. Polymersomes that are biodegradable and particular for a given target deliver their medications into tumor cell endosomes when they degrade in an acidic environment. A polymersome is made of two layers of synthetic polymers, which are much larger than individual phospholipids but share many of the same chemical properties. This is in contrast to cell membranes and liposomes, which are made of a double layer of phospholipids. The methods used to create liposomes are also employed to create polymersomes. The most popular technique is thin-film hydration, which involves first suspending diblock copolymers in a volatile organic solvent and drying them onto a glass or Teflon surface. The dried thin film is then hydrated in an aqueous solution that contains the chemical moieties that will be contained within the polymersomes, sonicated, and extruded to the required size. Since lengthy circulation periods and improved tumor accumulation are important for imaging applications, most polymersomes are shrunk to less than 150 nm in diameter. However, due to the high membrane durability, polymersomes with a diameter of tens of microns can also be created.

Keywords

Thin film, Copolymers, Microfluidic, Liposomes, Synthetic Polymers, Phospholipids, Tumor Regression

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

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