Madhu Goswami,
- Student, Department of Biotechnology, Gautam Buddha University, Greater Noida, Uttar Pradesh, India
Abstract
Gene editing technologies, particularly CRISPR/Cas9, have revolutionized the field of veterinary medicine, offering unprecedented opportunities for precise genetic manipulation in animals. This review explores the potential applications of gene editing in enhancing animal health, focusing on disease resistance, breeding programs, and the associated ethical considerations. Beginning with an overview of gene editing techniques, we discuss the utility of CRISPR/Cas9 in targeted genetic modifications and compare its advantages and limitations relative to other methods.
The review then examines the use of gene editing for disease resistance, showcasing case studies across various animal species, including livestock, companion animals, and aquaculture species. We highlight examples of targeted genetic modifications aimed at enhancing immunity against specific pathogens and discuss the potential implications for animal welfare and agricultural sustainability. Furthermore, we explore the role of gene editing in breeding programs, where it facilitates the introduction of desirable traits in animals through accelerated genetic manipulation. We delve into the considerations surrounding regulatory approval and public acceptance of gene-edited animals, recognizing the need for ethical evaluation and societal dialogue in this evolving landscape. Ethical considerations form a significant component of this review, encompassing discussions on animal welfare, rights, and human responsibility in genetic manipulation. We examine various ethical frameworks and perspectives, emphasizing the importance of thoughtful deliberation and informed decision-making in the application of gene editing technologies in veterinary medicine.
Finally, we address the regulatory landscape and future directions of gene editing in animal health, outlining current regulations, challenges in translation from research to commercial applications, and opportunities for personalized medicine and conservation efforts. This review provides a comprehensive overview of the potential of gene editing in animal health, underscoring the opportunities and challenges inherent in its integration into veterinary practice.
Keywords: Gene Editing, CRISPR/Cas9, Gene Editing Technologies, Animal health, Breeding Programs
[This article belongs to Research & Reviews : Journal of Veterinary Science and Technology (rrjovst)]
Madhu Goswami. Gene Editing and Its Implications for Animal Health. Research & Reviews : Journal of Veterinary Science and Technology. 2024; 13(01):13-17.
Madhu Goswami. Gene Editing and Its Implications for Animal Health. Research & Reviews : Journal of Veterinary Science and Technology. 2024; 13(01):13-17. Available from: https://journals.stmjournals.com/rrjovst/article=2024/view=146185
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Volume | 13 |
Issue | 01 |
Received | 26/04/2024 |
Accepted | 03/05/2024 |
Published | 15/05/2024 |