Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats

Year : 2024 | Volume :14 | Issue : 01 | Page : 10-16
By

    Ravi Babu.Birudu

  1. Jagadish Naik

  2. Awais Ali

  3. Waseef Ullah

  4. Syed Luqman Ali

  5. Majda Badaoui

  6. Hajar Arizada

  1. Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India
  2. Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India
  3. Research Scholar, Abdul wali Khan University, Mardan, Pakistan
  4. Research Scholar, Abdul wali Khan University, Mardan, Pakistan
  5. Research Scholar, Abdul wali Khan University, Mardan, Pakistan
  6. Research Scholar, Cadi Ayyad University, Marrakech, Morocco
  7. Research Scholar, Cadi Ayyad University, Marrakech, Morocco

Abstract

The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. “The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had mean values of 121.75 ± 4.33* and 124.90 ± 2.85*, respectively. The mean values of Ascorbic acid in normal rats was 0.50±0.27.Diet- induced diabetic rats have ascorbic acid mean 3.50±0.28. The normal rat’s mean of serum catalase was 112.55±1.76.Diet induced rats have mean a value of 125.78±1.96*.This value is significant. Diet-induced diabetic rats treated with a standard drug have a mean of 121.38 ± 1.68*. Diabetic rats treated with plant extracts of PSF (Passiflora foetida leaf) exhibit mean values of 123.47 ± 1.67*, 119.27 ± 4.38*, and 113.07 ± 3.82. The outcomes of our study indicate that both plant extracts and standard drugs improve the anti-oxidant levels.

Keywords: Anti-oxidants, Ascorbic acid, Glutathione peroxidase, Serum catalase, Plant extracts.

[This article belongs to Research & Reviews: A Journal of Pharmacology(rrjop)]

How to cite this article: Ravi Babu.Birudu, Jagadish Naik, Awais Ali, Waseef Ullah, Syed Luqman Ali, Majda Badaoui, Hajar Arizada.Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats.Research & Reviews: A Journal of Pharmacology.2024; 14(01):10-16.
How to cite this URL: Ravi Babu.Birudu, Jagadish Naik, Awais Ali, Waseef Ullah, Syed Luqman Ali, Majda Badaoui, Hajar Arizada , Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats rrjop 2024 {cited 2024 Mar 30};14:10-16. Available from: https://journals.stmjournals.com/rrjop/article=2024/view=137967


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Regular Issue Subscription Original Research
Volume 14
Issue 01
Received February 28, 2024
Accepted March 15, 2024
Published March 30, 2024
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