Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli

Year : 2024 | Volume :14 | Issue : 01 | Page : 32-47

Syed Asra Kirmani

Jasmina Javaid Shah

  1. Student Department of Chemical Microbiology, Rayat Bahra University, Mohali Punjab India
  2. Assistant Professor Department of Allied & Health Sciences, Rayat Bahra University, Mohali Punjab


Escherichia coli, commonly known as E. coli, is a prevalent bacterium capable of causing infections in humans. The development of antimicrobial resistance in E. coli poses a significant public health issue. This study aimed to determine the patient profile and antimicrobial susceptibility patterns of clinically isolated E. coli. A retrospective study was carried out on E. coli samples collected from clinical specimens within a hospital environment. Patient profiles, including age, gender, and underlying medical conditions, were recorded. Standard methods were employed to conduct antimicrobial susceptibility testing on the E. coli isolates, with interpretation of the results based on clinical breakpoints advised by the Clinical and Laboratory Standards Institute. The patient profile and antimicrobial susceptibility patterns of E. coli isolates were analyzed and presented. Descriptive statistics showed that the majority of patients were female and had urinary tract infections. Antimicrobial susceptibility testing revealed that E. coli isolates were highly resistant to ampicillin and sulfamethoxazole/trimethoprim, but susceptible to carba penems and amino glycosides. Correlations of notable significance were identified between age and antimicrobial resistance. These findings can inform the development of effective treatment strategies and antimicrobial stewardship programs to combat the spread of antimicrobial resistance in E. coli. The result of antibiotic susceptibility testing revealed varying patterns of resistance among the Escherichia coli isolates. Some strains exhibited a high degree of susceptibility to multiple antibiotics, while others demonstrated resistance, particularly to certain classes of antibiotics. Data analysis highlighted notable trends and correlations between specific antibiotics and resistance patterns. These findings hold crucial implications for informing suitable treatment approaches for Escherichia coli infections. Understanding the antibiotic susceptibility pattern of clinically isolated strains can aid healthcare providers in selecting effective antimicrobial therapies and minimizing the spread of resistant strains.

Keywords: Escherichia coli, Antibiotics, Antimicrobial susceptibility test, Model Organism, Culture media

[This article belongs to Research & Reviews: A Journal of Microbiology & Virology(rrjomv)]

How to cite this article: Syed Asra Kirmani, Jasmina Javaid Shah. Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli. Research & Reviews: A Journal of Microbiology & Virology. 2024; 14(01):32-47.
How to cite this URL: Syed Asra Kirmani, Jasmina Javaid Shah. Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli. Research & Reviews: A Journal of Microbiology & Virology. 2024; 14(01):32-47. Available from:

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Regular Issue Subscription Original Research
Volume 14
Issue 01
Received March 26, 2024
Accepted April 14, 2024
Published May 8, 2024